Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura A. Hecker"'
Publikováno v:
Cells, Vol 12, Iss 8, p 1142 (2023)
Mutations in the LMNA gene cause a collection of diseases known as laminopathies, including muscular dystrophies, lipodystrophies, and early-onset aging syndromes. The LMNA gene encodes A-type lamins, lamins A/C, intermediate filaments that form a me
Externí odkaz:
https://doaj.org/article/e0bb11c0fb8a41ef87a20bf88f0c0d91
Publikováno v:
Bioinformatics and Biology Insights, Vol 2008, Iss 2, Pp 401-412 (2008)
Externí odkaz:
https://doaj.org/article/afbd8a9fa49343ed9cc976834bcbc1ef
OBJECTIVE To determine if keratocyte populations are different in corneas with Fuchs dystrophy compared with control corneas. METHODS Eleven corneas excised during penetrating keratoplasty for Fuchs dystrophy and 5 control corneas of eyes enucleated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa0aff9debeb9f67aa7c26813743290
https://europepmc.org/articles/PMC3902089/
https://europepmc.org/articles/PMC3902089/
Autor:
Laura A, Hecker, Albert O, Edwards
Publikováno v:
Advances in experimental medicine and biology. 703
The major focus of our research is to understand how age-related macular degeneration (AMD) develops. It is known that genetic variation can explain much of the risk of developing AMD. However, we do not know what controls the transition between a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7696228e7ff425ca333f23cf7dc4e5b
https://pubmed.ncbi.nlm.nih.gov/20711706
https://pubmed.ncbi.nlm.nih.gov/20711706
Autor:
Albert O. Edwards, Laura A. Hecker
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781441956347
The major focus of our research is to understand how age-related macular degeneration (AMD) develops. It is known that genetic variation can explain much of the risk of developing AMD. However, we do not know what controls the transition between a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0997209410ef5628ac2c47729150b371
https://doi.org/10.1007/978-1-4419-5635-4_4
https://doi.org/10.1007/978-1-4419-5635-4_4
Autor:
Beatrix Pollok-Kopp, Laura A. Hecker, Peter Charbel Issa, Kent R. Bailey, Albert O. Edwards, Euijung Ryu, Hendrik P. N. Scholl, William L. Brown, Katharina E. Schmid-Kubista, Martin Oppermann, Nirubol Tosakulwong, Keith H. Baratz
Publikováno v:
Human molecular genetics. 19(1)
Activation of the alternative pathway of complement is implicated in common neurodegenerative diseases including age-related macular degeneration (AMD). We explored the impact of common variation in genes encoding proteins of the alternative pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9049dacc73c333fdaa4935d0fa1799f4
https://pubmed.ncbi.nlm.nih.gov/19825847
https://pubmed.ncbi.nlm.nih.gov/19825847
Autor:
Heather West Greenlee, Oksana Kohutyuk, Alison E Barnhill, Laura A. Hecker, Janice E. Buss, Vasant Honavar
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 3, Iss 1, p 25 (2010)
BMC Research Notes, Vol 3, Iss 1, p 25 (2010)
Background The process of rod photoreceptor genesis, cell fate determination and differentiation is complex and multi-factorial. Previous studies have defined a model of photoreceptor differentiation that relies on intrinsic changes within the presum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b32e113ac23534dc5ddacab4beb654
https://pubmed.ncbi.nlm.nih.gov/20181029
https://pubmed.ncbi.nlm.nih.gov/20181029
Autor:
Keith H. Baratz, Albert O. Edwards, Yanhong Wu, Nirubol Tosakulwong, Katharina E. Schmid-Kubista, Euijung Ryu, William L. Brown, Laura A. Hecker
Publikováno v:
Investigative Opthalmology & Visual Science. 50:5070
PURPOSE. To develop an assay for determining the number of copies of the genes encoding complement factor H related 3 (CFHR3) and 1 (CFHR1) and determine the contribution of copy number variation (CNV) at CFHR3 and CFHR1 to the development of age-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929239bec36d1375a56ed493904b2243
https://doi.org/10.1167/iovs.09-3975
https://doi.org/10.1167/iovs.09-3975
Publikováno v:
Bioinformatics and Biology Insights, Vol 2008, Iss 2, Pp 401-412 (2008)
Bioinformatics and Biology Insights, Vol 2 (2008)
Bioinformatics and Biology Insights
Bioinformatics and Biology Insights, Vol 2, Pp 91-102 (2008)
Bioinformatics and Biology Insights, Vol 2 (2008)
Bioinformatics and Biology Insights
Bioinformatics and Biology Insights, Vol 2, Pp 91-102 (2008)
Understanding the gene networks that orchestrate the differentiation of retinal progenitors into photoreceptors in the developing retina is important not only due to its therapeutic applications in treating retinal degeneration but also because the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df587732d4c327a432ddc860bff78f1
https://doi.org/10.4137/bbi.s417
https://doi.org/10.4137/bbi.s417