Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Laura A. Forney"'
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
FGF21 is a potent metabolic regulator of energy balance, body composition, lipid metabolism, and glucose homeostasis. Initial studies reported that it was increased by fasting and the associated increase in ketones, but more recent work points to the
Externí odkaz:
https://doaj.org/article/b4b1dab8185642aa86d153dd13313a7e
Autor:
Han Fang, Kirsten P. Stone, Laura A. Forney, Landon C. Sims, Gabriela C. Gutierrez, Sujoy Ghosh, Thomas W. Gettys
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102470- (2021)
Summary: Dietary methionine restriction (MR) is normally implemented using diets formulated from elemental amino acids (AA) that reduce methionine content to ∼0.17%. However, translational implementation of MR with elemental AA-based diets is intra
Externí odkaz:
https://doaj.org/article/a743b170ec9c4738875871336e1fbec9
Autor:
Tara M. Henagan, Laura K. Stewart, Laura A. Forney, Lauren M. Sparks, Neil Johannsen, Timothy S. Church
Publikováno v:
PPAR Research, Vol 2014 (2014)
PGC1α, a transcriptional coactivator, interacts with PPARs and others to regulate skeletal muscle metabolism. PGC1α undergoes splicing to produce several mRNA variants, with the NTPGC1α variant having a similar biological function to the full leng
Externí odkaz:
https://doaj.org/article/6a0e437d0a3d485dab58bcb0217a4c97
Publikováno v:
Annual Review of Nutrition. 42:201-226
The original description of dietary methionine restriction (MR) used semipurified diets to limit methionine intake to 20% of normal levels, and this reduction in dietary methionine increased longevity by ∼30% in rats. The MR diet also produces para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9603d69dd8f7782491ec838ceb8217c3
https://doi.org/10.1146/annurev-nutr-062320-111849
https://doi.org/10.1146/annurev-nutr-062320-111849
Autor:
David H. Burk, Thomas W. Gettys, Kirsten P. Stone, Amanda N. Gibson, Laura A. Forney, Han Fang, Leighann Y Vincik, Alicia M. Vick, Landon C. Sims
Publikováno v:
Obesity (Silver Spring)
Objective Restricting dietary methionine to 0.17% in mice increases energy expenditure (EE), reduces fat deposition, and improves metabolic health by increasing hepatic fibroblast growth factor 21 (FGF21). The goal of this study was to compare each o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903fd4486ff7ceb64893f0b9a13de553
https://doi.org/10.1002/oby.22919
https://doi.org/10.1002/oby.22919
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
FGF21 is a potent metabolic regulator of energy balance, body composition, lipid metabolism, and glucose homeostasis. Initial studies reported that it was increased by fasting and the associated increase in ketones, but more recent work points to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2520597d2343ff59cb0405fb2568fc31
https://doi.org/10.3389/fendo.2021.773975
https://doi.org/10.3389/fendo.2021.773975
Autor:
Narayan R Raju, Henry A. Palfrey, Subramanyam N. Murthy, Thomas W. Gettys, Avinash Kumar, Laura A. Forney, Kirsten P. Stone, Rashmi Pathak
Publikováno v:
Inflamm Res
OBJECTIVE: Hypercholesterolemia is associated with the development of a pro-inflammatory state and is a documented risk factor for progression to insulin resistance, nonalcoholic fatty liver and cardiovascular diseases. Sitagliptin is an incretin enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbf08a88b53486f5a404ef37f8f71b8
https://doi.org/10.1007/s00011-019-01243-x
https://doi.org/10.1007/s00011-019-01243-x
Autor:
Sujoy Ghosh, Laura A. Forney, Han Fang, Leighann Y Vincik, Kirsten P. Stone, Landon C. Sims, Thomas W. Gettys
Publikováno v:
Nutrients
Volume 13
Issue 6
Nutrients, Vol 13, Iss 1788, p 1788 (2021)
Volume 13
Issue 6
Nutrients, Vol 13, Iss 1788, p 1788 (2021)
The principal sensing of dietary methionine restriction (MR) occurs in the liver, where it activates multiple transcriptional programs that mediate various biological components of the response. Hepatic Fgf21 is a key target and essential endocrine m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c65adc70105e38a629868d5de1c898
Autor:
Han, Fang, Kirsten P, Stone, Sujoy, Ghosh, Laura A, Forney, Landon C, Sims, LeighAnn, Vincik, Thomas W, Gettys
Publikováno v:
Nutrients
The principal sensing of dietary methionine restriction (MR) occurs in the liver, where it activates multiple transcriptional programs that mediate various biological components of the response. Hepatic Fgf21 is a key target and essential endocrine m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84ba5524421fa1efc4f8a410a18b660d
https://pubmed.ncbi.nlm.nih.gov/34073838
https://pubmed.ncbi.nlm.nih.gov/34073838
Publikováno v:
Diabetes. 69
Restriction of methionine in rodent diets increases energy expenditure, limits weight gain, improves insulin sensitivity, and reduces hepatic and circulating lipids. Dietary methionine restriction (MR) is implemented using diets formulated from eleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c843fb82812a83a580bcdd8d24061ebb
https://doi.org/10.2337/db20-1868-p
https://doi.org/10.2337/db20-1868-p