Zobrazeno 1 - 6
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pro vyhledávání: '"Laura A. Filla"'
Publikováno v:
Analytical and bioanalytical chemistry. 411(24)
As microfluidic cell culture progresses, the need for robust and reproducible intracellular analyses grows. In particular, intracellular metabolites are subject to perturbation and degradation during the lysing process. The reliability of intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb07597ef6587b37d4bbf3b04379bb5
https://pubmed.ncbi.nlm.nih.gov/31372700
https://pubmed.ncbi.nlm.nih.gov/31372700
Autor:
Laura A. Filla, James L. Edwards
Publikováno v:
Molecular BioSystems. 12:1090-1105
With a global prevalence of 9%, diabetes is the direct cause of millions of deaths each year and is quickly becoming a health crisis. Major long-term complications of diabetes arise from persistent oxidative stress and dysfunction in multiple metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967186e06262b931bfc11792a64e15bc
https://doi.org/10.1039/c6mb00014b
https://doi.org/10.1039/c6mb00014b
Publikováno v:
Journal of Proteome Research
Despite the prevalence of diabetes and the global health risks it poses, the biochemical pathogenesis of diabetic complications remains poorly understood with few effective therapies. This study employs capillary liquid chromatography (capLC) and tan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf11ba1580d1121c6480abc196b53ce7
https://doi.org/10.1021/pr501030e
https://doi.org/10.1021/pr501030e
Sample pretreatment in conventional cellular metabolomics entails rigorous lysis and extraction steps which increase the duration as well as limit the consistency of these experiments. We report a biomimetic cell culture microfluidic device (MFD) whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a422335864ec875a70e5c77d1e2967
https://europepmc.org/articles/PMC4902300/
https://europepmc.org/articles/PMC4902300/
Publikováno v:
Analytical Chemistry. 83:5996-6003
Segmented flow in microfluidic devices involves the use of droplets that are generated either on- or off-chip. When used with off-chip sampling methods, segmented flow has been shown to prevent analyte dispersion and improve temporal resolution by pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5ddc3562475e7caf441f0a2433d6b6
https://doi.org/10.1021/ac201007s
https://doi.org/10.1021/ac201007s
In this communication, we demonstrate that a carbon ink microelectrode array, where the electrodes are held at the same potential, affords significant signal enhancement in microchip electrophoresis with amperometric detection. The ability to fabrica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984fd114a7c997f1832125aa59001cda
https://europepmc.org/articles/PMC3092702/
https://europepmc.org/articles/PMC3092702/