Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Laura A. Cox"'
Autor:
Timothy Leach, Uma Gandhi, Kimberly D. Reeves, Kristina Stumpf, Kenichi Okuda, Frank C. Marini, Stephen J. Walker, Richard Boucher, Jeannie Chan, Laura A. Cox, Anthony Atala, Sean V. Murphy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The human airways are complex structures with important interactions between cells, extracellular matrix (ECM) proteins and the biomechanical microenvironment. A robust, well-differentiated in vitro culture system that accurately models thes
Externí odkaz:
https://doaj.org/article/f6aec4b9509d461d8e54e25cfb50ccb8
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Identification of potential therapeutic targets and biomarkers indicative of burden of early atherosclerosis that occur prior to advancement to life-threatening unstable plaques is the key to eradication of CAD prevalence and incidences. We
Externí odkaz:
https://doaj.org/article/324255acddf5477e8c12386f671b6f23
Autor:
Amy Kelly, Jeannie Chan, Theresa L. Powell, Laura A. Cox, Thomas Jansson, Fredrick J. Rosario
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Infants born to obese mothers have an increased risk of developing obesity and metabolic diseases in childhood and adulthood. Although the molecular mechanisms linking maternal obesity during pregnancy to the development of metabolic diseases in offs
Externí odkaz:
https://doaj.org/article/e81e6aa845b44b9fbe11dab68f712d74
Autor:
Zeeshan Hamid, Kip D. Zimmerman, Hector Guillen-Ahlers, Cun Li, Peter Nathanielsz, Laura A. Cox, Michael Olivier
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Reliable and effective label-free quantification (LFQ) analyses are dependent not only on the method of data acquisition in the mass spectrometer, but also on the downstream data processing, including software tools, query databas
Externí odkaz:
https://doaj.org/article/be70a328eed04cc5b5b766e275146d58
Autor:
Susana P. Pereira, Mariana S. Diniz, Ludgero C. Tavares, Teresa Cunha-Oliveira, Cun Li, Laura A. Cox, Mark J. Nijland, Peter W. Nathanielsz, Paulo J. Oliveira
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15192 (2023)
Intra-uterine growth restriction (IUGR) is a common cause of fetal/neonatal morbidity and mortality and is associated with increased offspring predisposition for cardiovascular disease (CVD) development. Mitochondria are essential organelles in maint
Externí odkaz:
https://doaj.org/article/e991950850f94cecaec48cdef55e070e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Insulin resistance (IR) affects a quarter of the world’s adult population and is a major factor in the pathogenesis of cardio-metabolic disease. In this pilot study, we implemented a non-invasive breathomics approach, combined with random
Externí odkaz:
https://doaj.org/article/8e4796a346484652a8368056215afa81
Autor:
Laura A. Cox, Jeannie Chan, Prahlad Rao, Zeeshan Hamid, Jeremy P. Glenn, Avinash Jadhav, Vivek Das, Genesio M. Karere, Ellen Quillen, Kylie Kavanagh, Michael Olivier
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Dietary high fructose (HFr) is a known metabolic disruptor contributing to development of obesity and diabetes in Western societies. Initial molecular changes from exposure to HFr on liver metabolism may be essential to understand
Externí odkaz:
https://doaj.org/article/027e176990914d9fa4b758efaea0c266
Autor:
Emma Mask, Vida L. Hodara, Jessica E. Callery, Laura M. Parodi, Veronica Obregon-Perko, Shigeo Yagi, Jeremy Glenn, Patrice Frost, Elizabeth Clemmons, Jean L. Patterson, Laura A. Cox, Luis D. Giavedoni
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Nonhuman primates (NHP) are particularly important for modeling infections with viruses that do not naturally replicate in rodent cells. Zika virus (ZIKV) has been responsible for sporadic epidemics, but in 2015 a disseminated outbreak of ZIKV result
Externí odkaz:
https://doaj.org/article/736efdc9330849c99703e8cf5457ef5b
Autor:
Kimberly D. Reeves, Christopher M. Polk, Laura A. Cox, Robert T. Fairman, Gregory A. Hawkins, Catherine L. Passaretti, Mindy M. Sampson
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 2 (2022)
In this study, we used genomic sequencing to identify variants of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in healthcare workers with coronavirus disease 2019 (COVID-19) after receiving a booster vaccination. We compared symptoms, co
Externí odkaz:
https://doaj.org/article/8aa468dd84fb48beb253c738e403237d
Autor:
Sobha Puppala, Kimberly D. Spradling-Reeves, Jeannie Chan, Shifra Birnbaum, Deborah E. Newman, Anthony G. Comuzzie, Michael C. Mahaney, John L. VandeBerg, Michael Olivier, Laura A. Cox
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
The purpose of this study was to identify molecular mechanisms by which the liver influences total lesion burden in a nonhuman primate model (NHP) of cardiovascular disease with acute and chronic feeding of a high cholesterol, high fat (HCHF) diet. B
Externí odkaz:
https://doaj.org/article/a9db47c993c443df92cdd1064ff328e7