Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura A Woo"'
Autor:
Laura A. Woo, Kaitlyn L. Wintruba, Bethany Wissmann, Svyatoslav Tkachenko, Ewa Kubicka, Emily Farber, Ola Engkvist, Ian Barrett, Kenneth L. Granberg, Alleyn T. Plowright, Matthew J. Wolf, David L. Brautigan, Stefan Bekiranov, Qing-Dong Wang, Jeffrey J. Saucerman
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110485- (2024)
Summary: Mammalian hearts lose their regenerative potential shortly after birth. Stimulating the proliferation of preexisting cardiomyocytes is a potential therapeutic strategy for cardiac damage. In a previous study, we identified 30 compounds that
Externí odkaz:
https://doaj.org/article/1bf1716420a649368af21109efc59278
Autor:
Bryana N. Harris, Laura A. Woo, R. Noah Perry, Mete Civelek, Matthew J. Wolf, Jeffrey J. Saucerman
Cardiac diseases are characterized by the inability of adult mammalian hearts to overcome the loss of cardiomyocytes (CMs). Current knowledge in cardiac regeneration lacks a clear understanding of the molecular systems determining whether CMs will pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d7c597c2264a1e9b3ecb5b46913897f
https://doi.org/10.1101/2022.10.11.511763
https://doi.org/10.1101/2022.10.11.511763
Publikováno v:
Circulation Research. 129
Rationale: Heart failure is caused by the inability of adult mammalian hearts to overcome the loss of cardiomyocytes (CMs). This is due partly to the limited proliferative capacity of CMs, which exit the cell cycle and do not undergo cell division. C
Autor:
Jeffrey J. Saucerman, Alleyn T. Plowright, Ola Engkvist, David L. Brautigan, Stefan Bekiranov, Henrik Andersson, Laura A. Woo, Matthew J. Wolf, Svyatoslav Tkachenko, Qing-Dong Wang, Ian P. Barrett, Mei Ding, Lauren Drowley, Peter Åkerblad, Mike Firth
Publikováno v:
Journal of Molecular and Cellular Cardiology. 127:204-214
Over 5 million people in the United States suffer from heart failure, due to the limited ability to regenerate functional cardiac tissue. One potential therapeutic strategy is to enhance proliferation of resident cardiomyocytes. However, phenotypic s
Autor:
Emily F Ross, Maria F Ali, Laura A Woo, Sean R Chadwick, Eunji Lee, Ryan M Sangston, Chhavi Sood, Qi Zhang, Xiaomu Zhang, Christopher D Deppmann
Publikováno v:
eLS. :1-7