Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Laura A Struzyna"'
Autor:
Dimple Chouhan, Wisberty J. Gordián Vélez, Laura A. Struzyna, Dayo O. Adewole, Erin R. Cullen, Justin C. Burrell, John C. O’Donnell, D. Kacy Cullen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Axonal extension and retraction are ongoing processes that occur throughout all developmental stages of an organism. The ability of axons to produce mechanical forces internally and respond to externally generated forces is crucial for nervous system
Externí odkaz:
https://doaj.org/article/4aaa4ee50cfc40ecb13cae25c167e5f1
Autor:
D. Kacy Cullen, Wisberty J. Gordián-Vélez, Laura A. Struzyna, Dennis Jgamadze, James Lim, Kathryn L. Wofford, Kevin D. Browne, H. Isaac Chen
Publikováno v:
iScience, Vol 21, Iss , Pp 57-67 (2019)
Summary: Reestablishing cerebral connectivity is a critical part of restoring neuronal network integrity and brain function after trauma, stroke, and neurodegenerative diseases. Creating transplantable axon tracts in the laboratory is an unexplored s
Externí odkaz:
https://doaj.org/article/22127a45e185408099f6fe90c5f82d96
Autor:
Kritika S. Katiyar, Laura A. Struzyna, Joseph P. Morand, Justin C. Burrell, Basak Clements, Franco A. Laimo, Kevin D. Browne, Joachim Kohn, Zarina Ali, Harry C. Ledebur, Douglas H. Smith, D. Kacy Cullen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Strategies to accelerate the rate of axon regeneration would improve functional recovery following peripheral nerve injury, in particular for cases involving segmental nerve defects. We are advancing tissue engineered nerve grafts (TENGs) comprised o
Externí odkaz:
https://doaj.org/article/94c3a84b7693496cbc16aa2aa5b2c7a6
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 5, Pp 679-685 (2015)
Neural tissue engineering is premised on the integration of engineered living tissue with the host nervous system to directly restore lost function or to augment regenerative capacity following nervous system injury or neurodegenerative disease. Disc
Externí odkaz:
https://doaj.org/article/10ed62e15a944aa5a447a4a897febc34
Autor:
Douglas H. Smith, Justin C. Burrell, Kevin D. Browne, Kritika S. Katiyar, Mindy I. Ezra, John L. Dutton, Joseph P. Morand, Laura A. Struzyna, Franco A. Laimo, H. Isaac Chen, John A. Wolf, Hilton M. Kaplan, Joseph M. Rosen, Harry C. Ledebur, Eric L. Zager, Zarina S. Ali, D. Kacy Cullen
Publikováno v:
Science Advances. 8
Functional restoration following major peripheral nerve injury (PNI) is challenging, given slow axon growth rates and eventual regenerative pathway degradation in the absence of axons. We are developing tissue-engineered nerve grafts (TENGs) to simul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11673284071aa13ca604253e8b5cb223
https://doi.org/10.1126/sciadv.abm3291
https://doi.org/10.1126/sciadv.abm3291
Autor:
Laura A. Struzyna, Kevin D. Browne, Justin C. Burrell, Wisberty J. Gordián Vélez, Kathryn L. Wofford, Hilton M. Kaplan, N. Sanjeeva Murthy, H. Isaac Chen, John E. Duda, Rodrigo A. España, D. Kacy Cullen
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13985
Parkinson’s disease (PD) affects 1–2% of people over 65, causing significant morbidity across a progressive disease course. The classic PD motor deficits are caused by the degeneration of dopaminergic neurons in the substantia nigra pars compacta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142a238df4041677ff0270a38b9e8466
https://pubmed.ncbi.nlm.nih.gov/36430464
https://pubmed.ncbi.nlm.nih.gov/36430464
Autor:
D. Kacy Cullen, H. Isaac Chen, Laura A. Struzyna, John C. O'Donnell, Elisia M. Clark, John E. Duda
Publikováno v:
Current Opinion in Biomedical Engineering. 14:75-83
Although traditional small animal and cell culture models of neurodegenerative disease have been valuable in foundational discoveries, their inherent imprecision may have biased our understanding of etiology in humans and hindered translation of ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46be1299c91b7c01a8b5ecddc52848d5
https://doi.org/10.1016/j.cobme.2020.07.004
https://doi.org/10.1016/j.cobme.2020.07.004
Autor:
Dennis Jgamadze, H. Isaac Chen, Kevin D. Browne, James Lim, D. Kacy Cullen, Kathryn L. Wofford, Wisberty J. Gordián-Vélez, Laura A. Struzyna
Publikováno v:
iScience, Vol 21, Iss, Pp 57-67 (2019)
iScience
iScience
Summary Reestablishing cerebral connectivity is a critical part of restoring neuronal network integrity and brain function after trauma, stroke, and neurodegenerative diseases. Creating transplantable axon tracts in the laboratory is an unexplored st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7cb2fd73826fa360725b9005972bbb
http://www.sciencedirect.com/science/article/pii/S2589004219303839
http://www.sciencedirect.com/science/article/pii/S2589004219303839
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 13:2040-2054
The central feature of peripheral motor axons is their remarkable lengths as they project from a motor neuron residing in the spinal cord to distant target muscle. However, current in vitro models have not replicated this feature owing to challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911951e9c3ad5d1a815eb2c464fada3d
https://doi.org/10.1002/term.2955
https://doi.org/10.1002/term.2955
Autor:
Ashley D. Nemes, H. Isaac Chen, Laura A. Struzyna, Mijail D. Serruya, Dayo O. Adewole, Dmitriy Petrov, D. Kacy Cullen, Reuben H. Kraft, James P. Harris, John A. Wolf, Justin C. Burrell
Publikováno v:
Adv Funct Mater
Brain-computer interface and neuromodulation strategies relying on penetrating non-organic electrodes/optrodes are limited by an inflammatory foreign body response that ultimately diminishes performance. A novel "biohybrid" strategy is advanced, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac1c846dbb34b1f02bb07de58d8778c
https://pubmed.ncbi.nlm.nih.gov/34045935
https://pubmed.ncbi.nlm.nih.gov/34045935