Výsledky vyhledávání - "Laura A Sherer"

Akademický článek

Treatment with tumor-treating fields (TTFields) suppresses intercellular tunneling nanotube formation in vitro and upregulates immuno-oncologic biomarkers in vivo in malignant mesothelioma

Autor: Akshat Sarkari, Sophie Korenfeld, Karina Deniz, Katherine Ladner, Phillip Wong, Sanyukta Padmanabhan, Rachel I Vogel, Laura A Sherer, Naomi Courtemanche, Clifford Steer, Kerem Wainer-Katsir, Emil Lou

Publikováno v: eLife, Vol 12 (2023)

Disruption of intercellular communication within tumors is emerging as a novel potential strategy for cancer-directed therapy. Tumor-Treating Fields (TTFields) therapy is a treatment modality that has itself emerged over the past decade in active cli

Externí odkaz: https://doaj.org/article/ee9c74b5c07d4d3cbf92f71ca8b2008d

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Akademický článek

Computational tools for quantifying actin filament numbers, lengths, and bundling

Autor: Laura A. Sherer, Biswaprakash Mahanta, Naomi Courtemanche

Publikováno v: Biology Open, Vol 13, Iss 3 (2024)

Externí odkaz: https://doaj.org/article/2076aa6322c7455aba6a57bc67a1e3e3

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Akademický článek

Cooperative bundling by fascin generates actin structures with architectures that depend on filament length

Autor: Laura A. Sherer, Naomi Courtemanche

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

The assembly of actin-based structures with precisely defined architectures supports essential cellular functions, including motility, intracellular transport, and division. The geometric arrangements of the filaments within actin structures are stab

Externí odkaz: https://doaj.org/article/769576e446394ec5a5f8842d97d07002

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Nucleation limits the lengths of actin filaments assembled by formin

Autor: Naomi Courtemanche, Biswaprakash Mahanta, Mark E. Zweifel, Laura A. Sherer

Publikováno v: Biophys J

Formins stimulate actin polymerization by promoting both filament nucleation and elongation. Because nucleation and elongation draw upon a common pool of actin monomers, the rate at which each reaction proceeds influences the other. This interdepende

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8f0439fbad6a545fb878d63e6fe98e
https://europepmc.org/articles/PMC8553668/