Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Laura A N Peferoen"'
1
Akademický článek
Immune cell topography of head and neck cancer
Autor: Bernard A Fox, Rieneke van de Ven, Carmen Ballesteros-Merino, Tara Muijlwijk, Sonja H Ganzevles, Ruud H Brakenhoff, Jos B Poell, Dennis N L M Nijenhuis, C René Leemans, Laura A N Peferoen, Elisabeth Bloemena, Fatima Ekhlas
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Approximately 50% of head and neck squamous cell carcinomas (HNSCC) recur after treatment with curative intent. Immune checkpoint inhibitors are treatment options for recurrent/metastatic HNSCC; however, less than 20% of patients respond.
Externí odkaz: https://doaj.org/article/706241e19a784c6ebfc691493690aafb
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2
Akademický článek
Circulating T cell status and molecular imaging may predict clinical benefit of neoadjuvant PD-1 blockade in oral cancer
Autor: Tanja D de Gruijl, Rieneke van de Ven, K Hakki Karagozoglu, Pim de Graaf, Ronald Boellaard, Ruud H Brakenhoff, C René Leemans, Gerben J C Zwezerijnen, C Willemien Menke-van der Houven van Oordt, Iris H C Miedema, Niels E Wondergem, Jan-Jaap Hendrickx, Simone E J Eerenstein, Rolf J Bun, Dorien C Mulder, Jens Voortman, Albert D Windhorst, J Pascal Hagers, Laura A N Peferoen, Elisabeth Bloemena
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Addition of neoadjuvant immune checkpoint inhibition to standard-of-care interventions for locally advanced oral cancer could improve clinical outcome.Methods In this study, 16 evaluable patients with stage III/IV oral cancer were treated
Externí odkaz: https://doaj.org/article/3a0f349d6bd74bb79ff5d9ffc2077cbb
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3
Akademický článek
Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System
Autor: Erik Nutma, Démi van Gent, Sandra Amor, Laura A. N. Peferoen
Publikováno v: Cells, Vol 9, Iss 3, p 600 (2020)
Over the last decade knowledge of the role of astrocytes in central nervous system (CNS) neuroinflammatory diseases has changed dramatically. Rather than playing a merely passive role in response to damage it is clear that astrocytes actively maintai
Externí odkaz: https://doaj.org/article/1e20481e044b4474a101ad2eada61fe2
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4
Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System
Autor: Démi van Gent, Laura A. N. Peferoen, Erik Nutma, Sandra Amor
Publikováno v: Nutma, E, van Gent, D M, Amor, S & Peferoen, L A N 2020, ' Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System ', Cells, vol. 9, no. 3, 600 . https://doi.org/10.3390/cells9030600, https://doi.org/10.3390/cells9030600
Cells, Vol 9, Iss 3, p 600 (2020)
Cells
Over the last decade knowledge of the role of astrocytes in central nervous system (CNS) neuroinflammatory diseases has changed dramatically. Rather than playing a merely passive role in response to damage it is clear that astrocytes actively maintai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8238c67ac05926b2c5a7f9512977cd
https://research.vumc.nl/en/publications/e0b25d11-607e-4997-960f-87673aee480c
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5
Brain endothelial cell expression of SPARCL-1 is specific to chronic multiple sclerosis lesions and is regulated by inflammatory mediators in vitro
Autor: Hugo Vrenken, H.E. de Vries, Connie R. Jimenez, P Gami, Charlotte E. Teunissen, Sander R. Piersma, Jens Kuhle, Erik Nutma, Ellen Iacobaeus, S Durieux, R Gorter, C Derada Troletti, Lou Brundin, Joep Killestein, Laura A. N. Peferoen, Marleen J.A. Koel-Simmelink, Claire Bridel, Sandra Amor, Thang V. Pham
Publikováno v: Bridel, C, Koel-Simmelink, M J A, Peferoen, L, Derada Troletti, C, Durieux, S, Gorter, R, Nutma, E, Gami, P, Iacobaeus, E, Brundin, L, Kuhle, J, Vrenken, H, Killestein, J, Piersma, S R, Pham, T V, De Vries, H E, Amor, S, Jimenez, C R & Teunissen, C E 2018, ' Brain endothelial cell expression of SPARCL-1 is specific to chronic multiple sclerosis lesions and is regulated by inflammatory mediators in vitro ', Neuropathology and Applied Neurobiology, vol. 44, no. 4, pp. 404-416 . https://doi.org/10.1111/nan.12412
Neuropathology and Applied Neurobiology, 44(4), 404-416. Wiley-Blackwell
Aims Cell matrix modulating protein SPARCL-1 is highly expressed by astrocytes during CNS development and following acute CNS damage. Applying NanoLC-MS/MS to CSF of RRMS and SPMS patients, we identified SPARCL-1 as differentially expressed between t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377ebd707dfc7a756fdee71bafecde24
https://doi.org/10.1111/nan.12412
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6
Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss
Autor: Laura A. N. Peferoen, A L Görtz, Sandra Amor, Marianna Bugiani, Wouter H. Gerritsen, J M van Noort
Publikováno v: Görtz, A L, Peferoen, L A N, Gerritsen, W H, van Noort, J M, Bugiani, M & Amor, S 2018, ' Heat shock protein expression in cerebral X-linked adrenoleukodystrophy reveals astrocyte stress prior to myelin loss ', Neuropathology and Applied Neurobiology, vol. 44, no. 4, pp. 363-376 . https://doi.org/10.1111/nan.12399
Neuropathology and Applied Neurobiology, 44(4), 363-376. Wiley-Blackwell
AIMS: X-linked adrenoleukodystrophy (X-ALD) is a genetic white matter disorder in which demyelination occurs due to accumulation of very long-chain fatty acids. Inflammation in the brain white matter is a hallmark of the pathology of cerebral X-ALD,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a54cbf8df0e40918e9eb72fbefc716a
https://doi.org/10.1111/nan.12399
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7
Acute syphilitic meningitis in an HIV-infected patient
Autor: Alex Wagemakers, Joep Killestein, Wim Ang, Dagmar H. Hepp, Laura A. N. Peferoen
Publikováno v: Wagemakers, A, Hepp, D, Killestein, J, Peferoen, L & Ang, W 2018, ' Acute syphilitic meningitis in an HIV-infected patient ', IDCases, vol. 13, e00423 . https://doi.org/10.1016/j.idcr.2018.e00423
IDCases, 13:e00423. Elsevier Ltd
IDCases, Vol 13, Iss, Pp-(2018)
IDCases
We present a case of acute syphilitic meningitis in a 28-year old HIV-infected patient, presenting with a seizure. MRI revealed a meningeal lesion with cortical involvement, and the patient described previous treatment for syphilis. Final diagnosis w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbee8d26bec4cbaaa3f2edb13883f91b
https://research.vumc.nl/en/publications/43545325-85ae-422a-959b-fd540e8be434
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8
Case report: Persistently seronegative neuroborreliosis in an immunocompromised patient
Autor: N. W. C. J. van de Donk, Laura A. N. Peferoen, B. de Wever, Alex Wagemakers, E. J. Hendriks, F. F. Muller, C. W. Ang, Joppe W. Hovius, Marieke C. Visser
Publikováno v: BMC infectious diseases, 18(1):362. BioMed Central
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-5 (2018)
BMC Infectious Diseases, 18(1):362. BioMed Central
Wagemakers, A, Visser, M C, de Wever, B, Hovius, J W, van de Donk, N W C J, Hendriks, E J, Peferoen, L, Muller, F F & Ang, C W 2018, ' Case report: Persistently seronegative neuroborreliosis in an immunocompromised patient ', BMC Infectious Diseases, vol. 18, no. 1, 362 . https://doi.org/10.1186/s12879-018-3273-8
BMC Infectious Diseases
Background Infection with Borrelia burgdorferi sensu lato complex (B. b. sl) spirochetes can cause Lyme borreliosis, manifesting as localized infection (e.g. erythema migrans) or disseminated disease (e.g. Lyme neuroborreliosis). Generally, patients
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d1ac1b94d6fc431d925a87c316db1e
https://pure.amc.nl/en/publications/case-report-persistently-seronegative-neuroborreliosis-in-an-immunocompromised-patient(7de16025-58e4-4794-a986-bb70e6ac1a8b).html
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10
Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis
Autor: Wouter H. Gerritsen, Paul van der Valk, Sandra Amor, Kimberley Ummenthum, Daphne Y.S. Vogel, Priscilla D. A. M. Heijnen, Laura A. N. Peferoen, Christine D. Dijkstra, Marjolein Breur, Regina Peferoen-Baert
Publikováno v: Journal of Neuropathology and Experimental Neurology, 74(1), 48-63. Lippincott Williams and Wilkins
Peferoen, L A N, Vogel, D Y S, Ummenthum, K, Breur, M, Heijnen, P D A M, Gerritsen, W H, Peferoen-Baert, R M B, van der Valk, P, Dijkstra, C D & Amor, S 2015, ' Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis ', Journal of Neuropathology and Experimental Neurology, vol. 74, no. 1, pp. 48-63 . https://doi.org/10.1097/NEN.0000000000000149
Similar to macrophages, microglia adopt diverse activation states and contribute to repair and tissue damage in multiple sclerosis. Using reverse transcription-quantitative polymerase chain reaction and immunohistochemistry, we show that in vitro M1-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1780cc193d3fffc34ff8da559fb77337
https://doi.org/10.1097/nen.0000000000000149
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