Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Laura A Kelley"'
Autor:
Christina M Carlson, Elizabeth A Turpin, Lindsey A Moser, Kevin B O'Brien, Troy D Cline, Jeremy C Jones, Terrence M Tumpey, Jacqueline M Katz, Laura A Kelley, Jack Gauldie, Stacey Schultz-Cherry
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001136 (2010)
Transforming growth factor-beta (TGF-β), a multifunctional cytokine regulating several immunologic processes, is expressed by virtually all cells as a biologically inactive molecule termed latent TGF-β (LTGF-β). We have previously shown that TGF-
Externí odkaz:
https://doaj.org/article/c914a8ab6375431794ca62e848a92eeb
Publikováno v:
Journal of Avian Biology, Vol 2023, Iss 1-2, Pp n/a-n/a (2023)
Living with increasing urbanisation and human populations requires resourcefulness and flexibility in wild animals' behaviour. Animals have to adapt to anthropogenic novelty in habitat structure and resources that may not resemble, or be as beneficia
Externí odkaz:
https://doaj.org/article/31eaf262c49640f3bf77fe1c62e3efa2
Autor:
Daniel S. Costa, Isabel W. Kenny-Ganzert, Qiuyi Chi, Kieop Park, Laura C. Kelley, Aastha Garde, David Q. Matus, Junhyun Park, Shaul Yogev, Bob Goldstein, Theresa V. Gibney, Ariel M. Pani, David R. Sherwood
Publikováno v:
Development. 150
Cell invasion through basement membrane (BM) barriers is important in development, immune function and cancer progression. As invasion through BM is often stochastic, capturing gene expression profiles of actively invading cells in vivo remains elusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde34f0c780f39da4767a5bb2f14ff83
https://doi.org/10.1242/dev.201570
https://doi.org/10.1242/dev.201570
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 95K, Supplementary Figure 3. Morphometric analysis of CTTN distribution. Intensity of signal for IF staining for CTTN and actin was calculated based on 3D reconstracted confocal projections of the whole cell along the line drawn across the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9511b74af94118f801ce71a3b74ede
https://doi.org/10.1158/1541-7786.22511340
https://doi.org/10.1158/1541-7786.22511340
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 608K, Supplementary Figure 6. A. Representative BLI of lungs dissected from 4 groups of mice after 2 weeks of treatment as in Fig.7A-B. B. Quantification of BLI of dissected lungs from mice as in (A); 3 independent experiments, n=6/group, Avera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5b84e4ab1fb6a91a961235fe49bb04
https://doi.org/10.1158/1541-7786.22511331.v1
https://doi.org/10.1158/1541-7786.22511331.v1
Autor:
Elena N. Pugacheva, Matthew B. Smolkin, Varvara K. Kozyreva, Kristina M. Marinak, Yuriy V. Loskutov, Laura C. Kelley, Brandon C. Jones
Ibidi chemotactic invasion of MDA-MB-231 cells with CA-RhoA overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9035c12b3f8bee82ad1db24dcf3b3dfc
https://doi.org/10.1158/1541-7786.22511755.v1
https://doi.org/10.1158/1541-7786.22511755.v1
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
The prometastatic protein NEDD9 (neural precursor cell expressed, developmentally downregulated 9) is highly expressed in many cancers and is required for mesenchymal individual cell migration and progression to the invasive stage. Nevertheless, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82643d1cf28555eff2e8c9f79dab9874
https://doi.org/10.1158/1541-7786.c.6539916.v1
https://doi.org/10.1158/1541-7786.c.6539916.v1
Autor:
Elena N. Pugacheva, Matthew B. Smolkin, Varvara K. Kozyreva, Kristina M. Marinak, Yuriy V. Loskutov, Laura C. Kelley, Brandon C. Jones
Commonly upregulated in human cancers, the scaffolding protein NEDD9/HEF1 is a known regulator of mesenchymal migration and cancer cell plasticity. However, the functional role of NEDD9 as a regulator of different migration/invasion modes in the cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d056d499e1e3da99ce8ba4dc404907e
https://doi.org/10.1158/1541-7786.c.6540028.v1
https://doi.org/10.1158/1541-7786.c.6540028.v1
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDF - 131K, Supplementary Figure 5. Rescue of NEDD9-knockdown with CTTN deacetylation mimicking mutant. Immunoprecipitation of CTTN or myc-CTTN with anti-CTTN or anti-myc antibodies from MDA-MB-231 cells co-transfected with siRNA against NEDD9 (N1) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06694b9c0a62360a4e9183a9f905443a
https://doi.org/10.1158/1541-7786.22511334
https://doi.org/10.1158/1541-7786.22511334
Autor:
Elena N. Pugacheva, Scott A. Weed, Matthew B. Smolkin, Ryan J. Ice, Anuradha Rajulapati, Laura C. Kelley, Robin A. Calkins, Ryan H. Livengood, Sarah L. McLaughlin, Varvara K. Kozyreva
PDf - 35K, Supplementary Figure 4. F-actin pull down assay using lysates from MDA-MB-231 cells expressing shCon, shCTTN and shHDAC6 (HD6) as in Fig.4B (shCon, shHD6). Representative images of WB analysis of F-actin precipitates (P) and supernatant (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a088da88a8a35d1fc90520069231b7a
https://doi.org/10.1158/1541-7786.22511337
https://doi.org/10.1158/1541-7786.22511337