Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Laura A Bienvenu"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The global burden of ischemic heart disease is burgeoning for both men and women. Although advances have been made, the need for new sex-specific therapies targeting key differences in cardiovascular disease outcomes in men and women remains. Mineral
Externí odkaz:
https://doaj.org/article/2ca3a299e4684040a85af5ca9f50011c
Autor:
Laura A Bienvenu, Carolyn A. Haller, Amy Kate Searle, Xiaowei Wang, Ana Maluenda, Elliot L. Chaikof, James D. McFadyen, Eefang Yu, Karlheinz Peter
Publikováno v:
Circulation research. 127(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ac35966ed4fdea053ee810e167e801
https://pubmed.ncbi.nlm.nih.gov/32806996
https://pubmed.ncbi.nlm.nih.gov/32806996
Autor:
Poonam Sharma, Clara Liu Chung Ming, Xiaowei Wang, Laura A Bienvenu, Dominik Beck, Gemma Figtree, Andrew Boyle, Carmine Gentile
Publikováno v:
Biofabrication. 14:025003
Current preclinical in vitro and in vivo models of cardiac injury typical of myocardial infarction (MI, or heart attack) and drug induced cardiotoxicity mimic only a few aspects of these complex scenarios. This leads to a poor translation of findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d99d717a637fc92d1e719464649834
https://doi.org/10.1088/1758-5090/ac47d8
https://doi.org/10.1088/1758-5090/ac47d8
Publikováno v:
Cardiovascular Research. 115:1817-1819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fa2f91ad73857ec66d7afa59c9152f
https://doi.org/10.1093/cvr/cvz168
https://doi.org/10.1093/cvr/cvz168
Publikováno v:
Journal of Molecular and Cellular Cardiology. 112:8-15
Nitric oxide (NO) is an important regulator of cardiac function and plays a key role in ischemic cardioprotection. The role of chronic NO deficiency in coordinating ischemic vulnerability in female myocardium has not been established. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291ae348ca35edb8a2bcffc07ab93455
https://doi.org/10.1016/j.yjmcc.2017.08.012
https://doi.org/10.1016/j.yjmcc.2017.08.012
Autor:
Amanda J. Rickard, Jimmy D. Bell, Morag J. Young, Elizabeth K. Fletcher, Laura A. Bienvenu, James Morgan, Melissa E. Reichelt, Lea M.D. Delbridge
Publikováno v:
Hypertension. 66:970-977
Loss of mineralocorticoid receptor signaling selectively in cardiomyocytes can ameliorate cardiac fibrotic and inflammatory responses caused by excess mineralocorticoids. The aim of this study was to characterize the role of cardiomyocyte mineralocor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f454fc082a4dba5b152bddcb8ddbd924
https://doi.org/10.1161/hypertensionaha.115.05981
https://doi.org/10.1161/hypertensionaha.115.05981
Publikováno v:
Journal of the American College of Cardiology. 68:2667-2669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31fa4964104aa5315ccb8209a1cb341a
https://doi.org/10.1016/j.jacc.2016.10.011
https://doi.org/10.1016/j.jacc.2016.10.011
Autor:
Parisa Koutsifeli, Alicia J. Jenkins, Claire L. Curl, Chengxue Qin, Rebecca H. Ritchie, Kimberley M. Mellor, Laura A. Bienvenu, Antonia J.A. Raaijmakers, U. Varma, Miles J. De Blasio, Chanchal Chandramouli, Melissa E. Reichelt, Lea M.D. Delbridge
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Diabetic cardiomyopathy is a distinct pathology characterized by early emergence of diastolic dysfunction. Increased cardiovascular risk associated with diabetes is more marked for women, but an understanding of the role of diastolic dysfunction in f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ed074021ede4e109eb9d83654bacf0
https://pubmed.ncbi.nlm.nih.gov/29402990
https://pubmed.ncbi.nlm.nih.gov/29402990
Publikováno v:
Journal of Molecular and Cellular Cardiology. 75:162-173
Previous studies have shown that ventricular myocytes from female rats have smaller contractions and Ca(2+) transients than males. As cardiac contraction is regulated by the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) pathway, we hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79657c65d8f4d3701cb9d6a957cb02e0
https://doi.org/10.1016/j.yjmcc.2014.07.006
https://doi.org/10.1016/j.yjmcc.2014.07.006
Publikováno v:
Clinical Science. 125:409-421
MR (mineralocorticoid receptor) activation in the heart plays a central role in the development of cardiovascular disease, including heart failure. The MR is present in many cell types within the myocardium, including cardiomyocytes, macrophages and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69705fa771542e311beb2516bf09c43
https://doi.org/10.1042/cs20130050
https://doi.org/10.1042/cs20130050