Zobrazeno 1 - 10
of 9 634
pro vyhledávání: '"Laura, Williamson"'
Autor:
Basile Tessier‐Cloutier, Jasleen K Grewal, Martin R Jones, Erin Pleasance, Yaoqing Shen, Ellen Cai, Chris Dunham, Lynn Hoang, Basil Horst, David G Huntsman, Diana Ionescu, Anthony N Karnezis, Anna F Lee, Cheng Han Lee, Tae Hoon Lee, David DW Twa, Andrew J Mungall, Karen Mungall, Julia R Naso, Tony Ng, David F Schaeffer, Brandon S Sheffield, Brian Skinnider, Tyler Smith, Laura Williamson, Ellia Zhong, Dean A Regier, Janessa Laskin, Marco A Marra, C Blake Gilks, Steven JM Jones, Stephen Yip
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 4, Pp 395-407 (2022)
Abstract In this study, we evaluate the impact of whole genome and transcriptome analysis (WGTA) on predictive molecular profiling and histologic diagnosis in a cohort of advanced malignancies. WGTA was used to generate reports including molecular al
Externí odkaz:
https://doaj.org/article/a901dba17e554a43930f20607375541d
Publikováno v:
BMJ Open, Vol 13, Iss 5 (2023)
The COVID-19 pandemic has seen an increase in rapidly disseminated scientific evidence and highlighted that traditional evidence synthesis methods, such as time and resource intensive systematic reviews, may not be successful in responding to rapidly
Externí odkaz:
https://doaj.org/article/f5246d9603b44165a7c9f85ab7c63718
Autor:
Yiqun Zhang, Fengju Chen, Erin Pleasance, Laura Williamson, Cameron J. Grisdale, Emma Titmuss, Janessa Laskin, Steven J.M. Jones, Isidro Cortes-Ciriano, Marco A. Marra, Chad J. Creighton
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110023- (2021)
Summary: The global impact of somatic structural variants (SVs) on gene regulation in advanced tumors with complex treatment histories has been mostly uncharacterized. Here, using whole-genome and RNA sequencing from 570 recurrent or metastatic tumor
Externí odkaz:
https://doaj.org/article/edab694d74344c2b892a199e86fb5c24
Autor:
Colin Barnes
Publikováno v:
Health & Social Care in the Community. 16:215-216
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::901e5c3b4b030b6d885f5d22cc353e6c
https://doi.org/10.1111/j.1365-2524.2007.772_8.x
https://doi.org/10.1111/j.1365-2524.2007.772_8.x
Autor:
Laura Williamson, Hannah Glaab
Publikováno v:
BMC Medical Ethics, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Vaccine hesitancy is a growing threat to public health. The reasons are complex but linked inextricably to a lack of trust in vaccines, expertise and traditional sources of authority. Efforts to increase immunization uptake in chi
Externí odkaz:
https://doaj.org/article/0192277f95b54a2ea2908afd769ac8c3
Autor:
Irene S, Yu, Kathleen, Wee, Laura, Williamson, Emma, Titmuss, Jianghong, An, Sheida, Naderi-Azad, Corey, Metcalf, Stephen, Yip, Basil, Horst, Steven J M, Jones, Katherine, Paton, Brad H, Nelson, Marco, Marra, Janessa J, Laskin, Kerry J, Savage
Publikováno v:
Melanoma Research. 32:278-285
Uveal melanoma is the most common intraocular malignancy and has a poor prognosis compared to other melanoma subtypes with a median overall survival of 6-10 months. With immune checkpoint inhibitor therapy, either PD-1 inhibitor alone or combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19fa47867cbd3b274cd3ce847e8811f5
https://doi.org/10.1097/cmr.0000000000000810
https://doi.org/10.1097/cmr.0000000000000810
Autor:
Rafael Bejar, Anjana Rao, Yun Huang, Kun Zhang, Dinh Diep, Tiffany Tanaka, Laura Williamson, Minjung Lee, Emily C. Wheeler, Edahí González-Avalos, Chan-Wang Jerry Lio, Soo Park, Timothy Luger, Brian M. Reilly
DNA methyltransferase inhibitors (DNMTI) like 5-Azacytidine (5-Aza) are the only disease-modifying drugs approved for the treatment of higher-risk myelodysplastic syndromes (MDS), however less than 50% of patients respond, and there are no predictors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15751a727a4cd1f9bf11ada4fc5cc766
https://doi.org/10.1158/1541-7786.c.6544947.v1
https://doi.org/10.1158/1541-7786.c.6544947.v1
Autor:
Rafael Bejar, Anjana Rao, Yun Huang, Kun Zhang, Dinh Diep, Tiffany Tanaka, Laura Williamson, Minjung Lee, Emily C. Wheeler, Edahí González-Avalos, Chan-Wang Jerry Lio, Soo Park, Timothy Luger, Brian M. Reilly
A) Expression of hemoglobin genes which increase in terminally differentiated erythroid cells. B) Expression of key erythrocyte marker genes. TPM=Transcripts per kilobase million; a gene expression measure for RNAseq that normalizes for gene-length a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623466af5b0b36d4e69432ea7848fc64
https://doi.org/10.1158/1541-7786.22525878
https://doi.org/10.1158/1541-7786.22525878
Autor:
Rafael Bejar, Anjana Rao, Yun Huang, Kun Zhang, Dinh Diep, Tiffany Tanaka, Laura Williamson, Minjung Lee, Emily C. Wheeler, Edahí González-Avalos, Chan-Wang Jerry Lio, Soo Park, Timothy Luger, Brian M. Reilly
A) Dose-response curve of wild-type TF1 cell viability for three different lengths of 5-Aza treatments (1 dose per day for a total length of treatment between 1 and 3 days). Points represent replicates per condition, shaded region corresponds to 95%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00da746ccd74bf3f24f9df60068c0885
https://doi.org/10.1158/1541-7786.22525887.v1
https://doi.org/10.1158/1541-7786.22525887.v1
Autor:
Rafael Bejar, Anjana Rao, Yun Huang, Kun Zhang, Dinh Diep, Tiffany Tanaka, Laura Williamson, Minjung Lee, Emily C. Wheeler, Edahí González-Avalos, Chan-Wang Jerry Lio, Soo Park, Timothy Luger, Brian M. Reilly
Cells were treated with 100uM L-AA or vehicle 24hrs before DNA isolation. A) 5hmC dot blot for L-AA treated or untreated Cells. B) Standard curve of 5hmC densitometric signal vs. pmol (calculated from 5hmC standard with known 5hmC amount). C) Quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11adce67c9c056e6c144befbed6938cb
https://doi.org/10.1158/1541-7786.22525890.v1
https://doi.org/10.1158/1541-7786.22525890.v1