Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Laura, Solforosi"'
Autor:
Laura Solforosi, Lea M. M. Costes, Jeroen T. B. M. Tolboom, Katherine McMahan, Tochi Anioke, David Hope, Tetyana Murdza, Michaela Sciacca, Emily Bouffard, Julia Barrett, Cindy Wu, Nicole Hachmann, Jessica Miller, Jingyou Yu, Xuan He, Catherine Jacob-Dolan, Sietske K. Rosendahl Huber, Liesbeth Dekking, Ronnie Chamanza, Ying Choi, Karin Feddes-de Boer, Dan H. Barouch, Hanneke Schuitemaker, Roland C. Zahn, Frank Wegmann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Variant booster vaccines are a strategy to improve protection against SARS-CoV-2. Here, the authors find that both Wuhan-Hu-1-based Ad26.COV2.S or an Omicron-adapted booster vaccine provide robust immune responses and protection against Omicron in NH
Externí odkaz:
https://doaj.org/article/48f5d6d725c04fbe926ebad22c4e7481
Autor:
Sonia Marquez-Martinez, Selina Khan, Joan van der Lubbe, Laura Solforosi, Lea M. M. Costes, Ying Choi, Satish Boedhoe, Mieke Verslegers, Marjolein van Heerden, Wendy Roosen, Sandra De Jonghe, Hendy Kristyanto, Veronica Rezelj, Jenny Hendriks, Jan Serroyen, Jeroen Tolboom, Frank Wegmann, Roland C. Zahn
Publikováno v:
Vaccines, Vol 12, Iss 5, p 559 (2024)
Ad26.COV2.S vaccination can lead to vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare but severe adverse effect, characterized by thrombocytopenia and thrombosis. The mechanism of VITT induction is unclear and likely multifactorial, p
Externí odkaz:
https://doaj.org/article/0b70c99c6c794addab88f4e0e602e414
Autor:
Viki Bockstal, Maarten Leyssen, Dirk Heerwegh, Bart Spiessens, Cynthia Robinson, Jeroen N. Stoop, Ramon Roozendaal, Thierry Van Effelterre, Auguste Gaddah, Griet A. Van Roey, Laura Solforosi, Roland Zahn, Benoit Callendret, Jenny Hendriks, Kerstin Luhn, Macaya Douoguih, Hanneke Schuitemaker, Johan Van Hoof
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Without clinical efficacy data, vaccine protective effect may be extrapolated from animals to humans using an immunologic marker that correlates with protection in animals. This immunobridging approach was used for the two-dose Ebola vaccine
Externí odkaz:
https://doaj.org/article/62001c2a26ba43fdbeac3ea1080907ee
Autor:
Chelsea McLean, Karin Dijkman, Auguste Gaddah, Babajide Keshinro, Michael Katwere, Macaya Douoguih, Cynthia Robinson, Laura Solforosi, Dominika Czapska-Casey, Liesbeth Dekking, Yvonne Wollmann, Ariane Volkmann, Maria Grazia Pau, Benoit Callendret, Jerry Sadoff, Hanneke Schuitemaker, Roland Zahn, Kerstin Luhn, Jenny Hendriks, Ramon Roozendaal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn the absence of clinical efficacy data, vaccine protective effect can be extrapolated from animals to humans, using an immunological biomarker in humans that correlates with protection in animals, in a statistical approach called immuno
Externí odkaz:
https://doaj.org/article/aad84e5ba566494dbfbc8dd3349ac928
Autor:
Ramon Roozendaal, Laura Solforosi, Daniel J. Stieh, Jan Serroyen, Roel Straetemans, Anna Dari, Muriel Boulton, Frank Wegmann, Sietske K. Rosendahl Huber, Joan E. M. van der Lubbe, Jenny Hendriks, Mathieu Le Gars, Liesbeth Dekking, Dominika N. Czapska-Casey, Nuria Guimera, Sarah Janssen, Sarah Tete, Abishek Chandrashekar, Noe B. Mercado, Jingyou Yu, Wouter Koudstaal, Juan J. Perez-Ruixo, Jerry Sadoff, Dan H. Barouch, Hanneke Schuitemaker, Roland Zahn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection o
Externí odkaz:
https://doaj.org/article/c77c130d228d404b88e0e8b1e5e20f78
Autor:
Ramon Roozendaal, Jenny Hendriks, Thierry van Effelterre, Bart Spiessens, Liesbeth Dekking, Laura Solforosi, Dominika Czapska-Casey, Viki Bockstal, Jeroen Stoop, Daniel Splinter, Sarah Janssen, Ben van Baelen, Nadia Verbruggen, Jan Serroyen, Eline Dekeyster, Ariane Volkmann, Yvonne Wollmann, Ricardo Carrion, Luis D. Giavedoni, Cynthia Robinson, Maarten Leyssen, Macaya Douoguih, Kerstin Luhn, Maria Grazia Pau, Jerry Sadoff, An Vandebosch, Hanneke Schuitemaker, Roland Zahn, Benoit Callendret
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract It has been proven challenging to conduct traditional efficacy trials for Ebola virus (EBOV) vaccines. In the absence of efficacy data, immunobridging is an approach to infer the likelihood of a vaccine protective effect, by translating vacc
Externí odkaz:
https://doaj.org/article/31753f8ec19c4f7ca129201ac99ccb00
Autor:
Machteld M. Tiemessen, Laura Solforosi, Liesbeth Dekking, Dominika Czapska-Casey, Jan Serroyen, Nancy J. Sullivan, Ariane Volkmann, Maria Grazia Pau, Benoit Callendret, Hanneke Schuitemaker, Kerstin Luhn, Roland Zahn, Ramon Roozendaal
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1263 (2022)
The Marburg virus (MARV) and Sudan virus (SUDV) belong to the filovirus family. The sporadic human outbreaks occur mostly in Africa and are characterized by an aggressive disease course with high mortality. The first case of Marburg virus disease in
Externí odkaz:
https://doaj.org/article/da2eb72a5deb4a68a93957d1fb5e72b3
Autor:
Laurens P Kil, Joost Vaneman, Joan E M van der Lubbe, Dominika Czapska-Casey, Jeroen T B M Tolboom, Ramon Roozendaal, Roland C Zahn, Harmjan Kuipers, Laura Solforosi
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225063 (2019)
Correlates of protection (CoP) are invaluable for iterative vaccine design studies, especially in pursuit of complex vaccines such as a universal influenza vaccine (UFV) where a single antigen is optimized to elicit broad protection against many vira
Externí odkaz:
https://doaj.org/article/2c43560738414ddbbd753da589cbbf12
Autor:
Roberto Burioni, Laura Solforosi, Massimo Clementi, Roberta A. Diotti, Matteo Castelli, Elena Criscuolo, Nicola Clementi, Giuseppe Sautto, Mancini Nicasio
Publikováno v:
Viruses, Vol 4, Iss 9, Pp 1731-1752 (2012)
The immune response against some viral pathogens, in particular those causing chronic infections, is often ineffective notwithstanding a robust humoral neutralizing response. Several evasion mechanisms capable of subverting the activity of neutralizi
Externí odkaz:
https://doaj.org/article/11f962e336eb47f9a0a1fe18a9ee70a8
Autor:
John Collinge, Cheng Fang, Laura Solforosi, David A. Harris, David Mengel, Grant T. Corbett, Alexandra DeSousa, Wen Liu, Matthew P. Frosch, Wei Hong, Dominic M. Walsh
Publikováno v:
Brain Res
Background The prion protein (PrP) is known to bind certain soluble aggregates of the amyloid β-protein (Aβ), and two regions of PrP, one centered around residues 19–33, and the other around 87–112, are thought to be particularly important for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788dff82cbb7e6938b8ebb4848646c61
https://doi.org/10.1016/j.brainres.2018.12.038
https://doi.org/10.1016/j.brainres.2018.12.038