Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Laura, Rassenti"'
Autor:
Janek S. Walker, Zachary A. Hing, Bonnie Harrington, Jordan Baumhardt, Hatice Gulcin Ozer, Amy Lehman, Brian Giacopelli, Larry Beaver, Katie Williams, Jordan N. Skinner, Casey B. Cempre, Qingxiang Sun, Sharon Shacham, Benjamin R. Stromberg, Matthew K. Summers, Lynne V. Abruzzo, Laura Rassenti, Thomas J. Kipps, Sameer Parikh, Neil E. Kay, Kerry A. Rogers, Jennifer A. Woyach, Vincenzo Coppola, Yuh Min Chook, Christopher Oakes, John C. Byrd, Rosa Lapalombella
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Abstract Background Exportin 1 (XPO1/CRM1) is a key mediator of nuclear export with relevance to multiple cancers, including chronic lymphocytic leukemia (CLL). Whole exome sequencing has identified hot-spot somatic XPO1 point mutations which we foun
Externí odkaz:
https://doaj.org/article/5d10b5b0f27b4de5a2529f4fedcb0538
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Non-uniform dynamics of single CpGs among CLL progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb264cc5bd8785cc56f7f7df4a4aa51c
https://doi.org/10.1158/2643-3230.22542277
https://doi.org/10.1158/2643-3230.22542277
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Table of correlation between time points within one sample and number of hyper- or hypomethylated CpGs for all CLL (top) and naïve and memory B cell samples (bottom)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a60c5fa8fe9ac2c439fffb59f48c2a
https://doi.org/10.1158/2643-3230.22542256.v1
https://doi.org/10.1158/2643-3230.22542256.v1
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Supplementary Figures 1-7 and matching legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052b420a6633dd0b86f90c667ce83a5c
https://doi.org/10.1158/2643-3230.22542265
https://doi.org/10.1158/2643-3230.22542265
Autor:
Alexander Meissner, Catherine J. Wu, Andreas Gnirke, Elias Campo, Thomas J. Kipps, Bernd Timmermann, Sven Klages, Donna S. Neuberg, Kenneth J. Livak, Shuqiang Li, Lili Wang, Jennifer R. Brown, Stacey M. Fernandes, Neil E. Kay, Tait D. Shanafelt, Esteban Braggio, Susan L. Slager, Connie Lesnick, Arman W. Mohammad, Laura Rassenti, Hongcang Gu, Michaela Gruber, Kendell Clement, Camilla K. Lemvigh, Noelia Purroy, Anat Biran, Helene Kretzmer
Most human cancers converge to a deregulated methylome with reduced global levels and elevated methylation at select CpG islands. To investigate the emergence and dynamics of the cancer methylome, we characterized genome-wide DNA methylation in prene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0465fb04b233bbc5e5b4e45d434aa6
https://doi.org/10.1158/2643-3230.c.6549850
https://doi.org/10.1158/2643-3230.c.6549850
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
XLSX file 47K, Supplementary table 1: Clinical and biological features of all samples and timepoints used in the study including all genetic alterations found per sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508ce1f0884cea31471d7bc1c4d3d9cc
https://doi.org/10.1158/2159-8290.22530033.v1
https://doi.org/10.1158/2159-8290.22530033.v1
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
XLSX file 15K, Supplementary table 2: Primer sequences used for targeted bisulfite-sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d90973ebf8445075d122508642fbea
https://doi.org/10.1158/2159-8290.22530030.v1
https://doi.org/10.1158/2159-8290.22530030.v1
Autor:
Christoph Plass, Thorsten Zenz, John C. Byrd, Stephan Stilgenbauer, Hartmut Döhner, Peter Lichter, Daniel Mertens, Thomas J. Kipps, Laura Rassenti, Christopher R. Schmidt, Olga Bogatyrova, David Brocks, Matthias Bieg, Manuela Zucknick, Jennifer Hüllein, Yassen Assenov, Lei Gu, Rainer Claus, Christopher C. Oakes
PDF file 1498K, Supplemental figures 1-10: Methylation analysis of CLL and healthy donor samples using 450k arrays, WGBS and targeted BS-seq, including technical evaluations of the methods used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44bcce678c83aecf1cbcf1807266c58
https://doi.org/10.1158/2159-8290.22530036.v1
https://doi.org/10.1158/2159-8290.22530036.v1
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
B-cell chronic lymphocytic leukemia (B-CLL) is the most common human leukemia in the world. Deregulation of the TCL1 oncogene is a causal event in the pathogenesis of the aggressive form of this disease as was verified by using animal models. To stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e6b405560a65b6341d3f41e0259b39
https://doi.org/10.1158/0008-5472.c.6495971.v1
https://doi.org/10.1158/0008-5472.c.6495971.v1
Autor:
Carlo M. Croce, Thomas Kipps, John P. Hagan, George A. Calin, Laura Rassenti, Chang-Gong Liu, Hansjuerg Alder, Stefano Volinia, Vadim Maximov, Alexey Efanov, Alexey Palamarchuk, Amelia Cimmino, Urmila Santanam, Yuri Pekarsky
PDF file, 654KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2248d78058d77d93e4165e3058b0b6
https://doi.org/10.1158/0008-5472.22368464
https://doi.org/10.1158/0008-5472.22368464