Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Laura, Lucarini"'
Autor:
Debora Collotta, Laura Lucarini
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/d31a823835954fd8a8fc89c28fdadecc
Autor:
Matteo Becatti, Andrea Bencini, Silvia Nistri, Luca Conti, Maria Giulia Fabbrini, Laura Lucarini, Veronica Ghini, Mirko Severi, Claudia Fiorillo, Claudia Giorgi, Lorenzo Sorace, Barbara Valtancoli, Daniele Bani
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Abstract Oxidative stress due to excess superoxide anion ($${{\bf{O}}}_{{\bf{2}}}^{{\boldsymbol{\cdot }}{\boldsymbol{-}}}$$ O2⋅− ) produced by dysfunctional mitochondria is a key pathogenic event of aging and ischemia-reperfusion diseases. Here,
Externí odkaz:
https://doaj.org/article/04182cdca23f47ec9e1ab153252d5613
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
It is known that fructose may contribute to myocardial vulnerability to ischemia/reperfusion (I/R) injury. D-tagatose is a fructose isomer with less caloric value and used as low-calorie sweetener. Here we compared the metabolic impact of fructose or
Externí odkaz:
https://doaj.org/article/041abf166ee64307b195e06e1b83498e
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 609 (2022)
The first properties of histamine (HA) that were elucidated were vasodilation and contraction of smooth muscles in the gut after stimulating gastric acid secretion and constriction of the bronchial area during anaphylaxis [...]
Externí odkaz:
https://doaj.org/article/64fcba5f8b33422187202b06d7ffc401
Autor:
Laura Lucarini, Lucia Magnelli, Nicola Schiavone, Alfonso Crisci, Alessio Innocenti, Luca Puccetti, Fabio Cianchi, Sara Peri, Claudiu T. Supuran, Laura Papucci, Emanuela Masini
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 234-240 (2018)
Carbonic anhydrase (CA, EC 4.2.1.1) IX is regarded as a tumour hypoxia marker and CA inhibitors have been proposed as a new class of antitumor agents, with one such agent in Phase II clinical trials. The expression of some CAs, in particular the isof
Externí odkaz:
https://doaj.org/article/2ebfe3c48516407eaa04726555ea7539
Autor:
Laura Micheli, Mariaconcetta Durante, Elena Lucarini, Silvia Sgambellone, Laura Lucarini, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Emanuela Masini
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1447 (2021)
A3 adenosine receptor (A3AR) agonists have emerged as potent relievers of neuropathic pain by a T cell-mediated production of IL-10. The H4 histamine receptor (H4R), also implicated in pain modulation, is expressed on T cells playing a preeminent rol
Externí odkaz:
https://doaj.org/article/01853348a7bd46b088b5f52888789778
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1186 (2021)
Glaucoma is a multifactorial neuropathy characterized by increased intraocular pressure (IOP), and it is the second leading cause of blindness worldwide after cataracts. Glaucoma combines a group of optic neuropathies characterized by the progressive
Externí odkaz:
https://doaj.org/article/8454c617b512406ea86cb692a13cd2aa
Autor:
Maria Luisa Eliana Luisi, Laura Lucarini, Barbara Biffi, Elena Rafanelli, Giacomo Pietramellara, Mariaconcetta Durante, Sofia Vidali, Gustavo Provensi, Sara Madiai, Chiara Francesca Gheri, Emanuela Masini, Maria Teresa Ceccherini
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Introduction: The Mediterranean Diet (MD) is useful in the prevention of overweight, obesity and metabolic disease. High Quality-Extra Virgin Olive Oil (HQ-EVOO), an essential component of this diet, exerts protective effects against chronic diseases
Externí odkaz:
https://doaj.org/article/8da9e74c06884ddf8a496f747d322ff0
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Patrizia Nardini, Alessandro Pini, Flavio Moroni, Emanuela Masini, Laura Lucarini
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Pulmonary fibrosis is the most frequent form of interstitial lung disease. Effective therapies are not yet available; novel therapeutic approaches are needed for counteracting fibrosis. Poly(ADP-ribose) polymerases are enzymes, involved in DNA repair
Externí odkaz:
https://doaj.org/article/5c92be04260341febbbfc88a6cf766b6
Autor:
Silvia Sgambellone, Silvia Marri, Serafina Villano, Emanuela Masini, Gustavo Provensi, Elena Bastia, Corinna Galli, Stefania Brambilla, Francesco Impagnatiello, Laura Lucarini
NCX 470, a nitric oxide (NO)-donating bimatoprost, was shown to ameliorate ocular hemodynamics and retinal physiology in rabbits following endothelin-1 (ET-1)-induced ischemia/reperfusion. Here we used the same model to compare NCX 470 (0.1% bid) to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c30f3accfbc09d27ede441bc89c672c
https://doi.org/10.20944/preprints202305.0309.v1
https://doi.org/10.20944/preprints202305.0309.v1
