The Bric-à-Brac BTB/POZ transcription factors are necessary in niche cells for germline stem cells establishment and homeostasis through control of BMP/DPP signaling in the Drosophila melanogaster ovary.

Autor: Laurine Miscopein Saler, Virginie Hauser, Mathieu Bartoletti, Charlotte Mallart, Marianne Malartre, Laura Lebrun, Anne-Marie Pret, Laurent Théodore, Fabienne Chalvet, Sophie Netter

Publikováno v: PLoS Genetics, Vol 16, Iss 11, p e1009128 (2020)

Many studies have focused on the mechanisms of stem cell maintenance via their interaction with a particular niche or microenvironment in adult tissues, but how formation of a functional niche is initiated, including how stem cells within a niche are

Externí odkaz: https://doaj.org/article/42d593a753d846378a56f4d500fe4604

An archaeal compound as a driver of Parkinson’s disease pathogenesis

Autor: Paul Wilmes, Jean-Pierre Trezzi, Velma Aho, Christian Jäger, Sebastian Schade, Annette Janzen, Oskar Hickl, Benoit Kunath, Mélanie Thomas, Kristopher Schmit, Pierre Garcia, Alessia Sciortino, Camille Martin-Gallausiaux, Rashi Halder, Oihane Uriarte Huarte, Tony Heurtaux, Ursula Heins-Marroquin, Gemma Gomez-Giro, Katrin Weidenbach, Léa Delacour, Cédric Laczny, Polina Novikova, Javier Ramiro-Garcia, Randolph Singh, Begoña Talavera Andújar, Laura Lebrun, Annegrait Daujeumont, Janine Habier, Xiangyi Dong, Floriane Gavotto, Anna Heintz-Buschart, Jochen Schneider, Nico Jehmlich, Martin von Bergen, Emma Schymanski, Ruth Schmitz, Jens Schwamborn, Enrico Glaab, Carole Linster, Toshimori Kitami, Manuel Buttini, Patrick May, Claudia Trenkwalder, Wolfgang Oertel, Brit Mollenhauer

Publikováno v: Under Review at Nature Portfolio. (Research Square Platform LLC) In Press

Patients with Parkinson’s disease (PD) exhibit differences in their gut microbiomes compared to healthy individuals. Although differences have most commonly been described in the abundances of bacterial taxa, changes to viral and archaeal populatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f522cd65c9b0ae0a2cc5a97d6a362a
http://orbilu.uni.lu/handle/10993/51987

Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance

Autor: James M. Schupp, Emilie E. L. Muller, Christian Jäger, Paul Keim, Laura Lebrun, Haixu Tang, Malte Herold, Paul Wilmes, Hugo Roume, Sujun Li, Michael R. Hoopmann, John D. Gillece, Patrick May, Abdul Sheik, Benoit J. Kunath, Luise A. K. Kleine-Borgmann, Irina Bessarab, Cedric Christian Laczny, Susana Martinez Arbas, Rohan Benjamin Hugh Williams, Yuzhen Ye, Anna Heintz-Buschart, Robert L. Moritz, Shaman Narayanasamy

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-19006-2⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)

The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a508d5887429a06c8acf64388295318
https://doi.org/10.1038/s41467-020-19006-2

Expressed protein profile of a Tectomicrobium and other microbial symbionts in the marine sponge Aplysina aerophoba as evidenced by metaproteomics

Autor: Laura Lebrun, Maryam Chaib De Mares, Diego Javier Jiménez, Paul Wilmes, Emilie E. L. Muller, Detmer Sipkema, Giorgia Palladino, Johanna Gutleben, Jan Dirk van Elsas

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), ⟨10.1038/s41598-018-30134-0⟩
Scientific Reports, 8:11795. Nature Publishing Group
Scientific reports, 8(1), 11795. England (2018).
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports 8 (2018) 1
Scientific Reports, 8(1)

Aplysina aerophoba is an emerging model marine sponge, with a well-characterized microbial community in terms of diversity and structure. However, little is known about the expressed functional capabilities of its associated microbes. Here, we presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b387d9a0c38f24ce1de13883fce5def
https://hal.archives-ouvertes.fr/hal-02328156

Sequential Isolation of DNA, RNA, Protein, and Metabolite Fractions from Murine Organs and Intestinal Contents for Integrated Omics of Host–Microbiota Interactions

Autor: Emilie E. L. Muller, Linda Wampach, Laura Lebrun, Paul Wilmes, Pranjul Shah

Publikováno v: Methods in Molecular Biology ISBN: 9781493986934
Microbial Proteomics, Methods and Protocols
Microbial Proteomics, Methods and Protocols, pp.279-291, 2018, ⟨10.1007/978-1-4939-8695-8_19⟩

The gastrointestinal microbiome plays a central role in health and disease. Imbalances in the microbiome, also referred to as dysbiosis, have recently been associated with a number of human idiopathic diseases ranging from metabolic to neurodegenerat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49e9319eed58f99d6edc2400e8db14f
https://doi.org/10.1007/978-1-4939-8695-8_19