Výsledky vyhledávání - "Laura, Kresty"

Akademický článek

Predicting Regression of Barrett’s Esophagus—Can All the King’s Men Put It Together Again?

Autor: Martin Tobi, Nabiha Khoury, Omar Al-Subee, Seema Sethi, Harvinder Talwar, Michael Kam, James Hatfield, Edi Levi, Jason Hallman, Mary Pat Moyer, Laura Kresty, Michael J. Lawson, Benita McVicker

Publikováno v: Biomolecules, Vol 14, Iss 9, p 1182 (2024)

The primary pre-neoplastic lesion of the lower esophagus in the vicinity of the gastroesophageal junction (GEJ) is any Barrett’s esophageal lesions (BE), and esophageal neoplasia has increased in the US population with predispositions (Caucasian ma

Externí odkaz: https://doaj.org/article/d8413cf86e034390af297b6971cb2f89

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Akademický článek

Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis

Autor: Gang Cheng, Qi Zhang, Jing Pan, Yongik Lee, Olivier Ouari, Micael Hardy, Monika Zielonka, Charles R. Myers, Jacek Zielonka, Katherine Weh, Andrew C. Chang, Guoan Chen, Laura Kresty, Balaraman Kalyanaraman, Ming You

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Brain metastases are a major reason for lung cancer mortality. Here, the authors modify lonidamine to target mitochondria, and show its therapeutic efficacy in inhibiting lung cancer brain metastasis by inducing autophagic cell death in cancer cells.

Externí odkaz: https://doaj.org/article/2a91f216e7964b0b95ec04c9938932cc

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Role of IL4 and GMCSF in Predicting Survival in Esophageal Cancer

Autor: Ryan J, Rebernick, Hannah N, Bell, Tyler M, Bauer, Dyke, McEwen, Douglas F, Werkman, Andrew C, Chang, Jules, Lin, Rishindra M, Reddy, Laura, Kresty, Kiran, Lagisetty

Publikováno v: Journal of the American College of Surgeons. 236:107-115

Esophageal cancer (EC) originates in the setting of chronic inflammation. Although previous studies have sought to understand the role of inflammatory signaling in EC, the effect of these immunologic changes on patient outcomes remains understudied.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeaa3ea865c3a9ed93d20cac5431d6a
https://doi.org/10.1097/xcs.0000000000000446

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Abstract 6141: Mechanisms by which Mito-lonidamine inhibits EGFR mutant lung cancer

Autor: Katherine M. Weh, Connor Howard, Yun Zhang, Jean-Jack Riethoven, Jennifer Clarke, Gang Cheng, Balaraman Kalyanaraman, Ming You, Laura Kresty

Publikováno v: Cancer Research. 83:6141-6141

Lung cancer remains the leading cause of cancer mortality. Efficacious targeted therapy options are urgently needed for lung cancer prevention and treatment. Epidermal growth factor receptor (EGFR) mutant lung cancer represents about 15% of lung canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2707884e9125f631f86a1afd2dd66d6
https://doi.org/10.1158/1538-7445.am2023-6141

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Cranberry Polyphenols in Esophageal Cancer Inhibition: New Insights

Autor: Jennifer Clarke, Laura Kresty, Amy Howell, Katherine Weh, Yun Zhang, Naomi Laventhal, Connor Howard

Publikováno v: Nutrients; Volume 14; Issue 5; Pages: 969

Esophageal adenocarcinoma (EAC) is a cancer characterized by rapidly rising incidence and poor survival, resulting in the need for new prevention and treatment options. We utilized two cranberry polyphenol extracts, one proanthocyanidin enriched (C-P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98bbaaa3d493b7d14b7137d0f233ad13
https://pubmed.ncbi.nlm.nih.gov/35267943

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