Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Laura, Giovati"'
Autor:
Lorenza Artesani, Tecla Ciociola, Alice Vismarra, Cristina Bacci, Stefania Conti, Laura Giovati
Publikováno v:
Antibiotics, Vol 13, Iss 8, p 683 (2024)
Bacterial resistance to β-lactam antibiotics, particularly new generation cephalosporins, is a major public health concern. In Escherichia coli, resistance to these antibiotics is mainly mediated by extended-spectrum β-lactamases (ESBL), which comp
Externí odkaz:
https://doaj.org/article/3c10ce7d84144173aefe47723071c809
Autor:
Tecla Ciociola, Laura Giovati, Tiziano De Simone, Greta Bergamaschi, Alessandro Gori, Valerio Consalvi, Stefania Conti, Alberto Vitali
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 472 (2023)
Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover, due to the small number of antifungal classes, therapy options
Externí odkaz:
https://doaj.org/article/743c7a4a71804ef58e96b37731350c60
Autor:
Mariana Gallo, Laura Giovati, Walter Magliani, Thelma A. Pertinhez, Stefania Conti, Elena Ferrari, Alberto Spisni, Tecla Ciociola
Publikováno v:
Journal of Fungi, Vol 8, Iss 7, p 723 (2022)
The ubiquitous commensal Candida albicans, part of the human microbiota, is an opportunistic pathogen able to cause a wide range of diseases, from cutaneous mycoses to life-threatening infections in immunocompromised patients. Candida albicans adapts
Externí odkaz:
https://doaj.org/article/bfd1b77c4b2d4617bbaf3ffd41ea455f
Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases
Autor:
Giannamaria Annunziato, Laura Giovati, Andrea Angeli, Marialaura Pavone, Sonia Del Prete, Marco Pieroni, Clemente Capasso, Agostino Bruno, Stefania Conti, Walter Magliani, Claudiu T. Supuran, Gabriele Costantino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1537-1544 (2018)
Infections caused by pathogens resistant to the available antimicrobial treatments represent nowadays a threat to global public health. Recently, it has been demonstrated that carbonic anhydrases (CAs) are essential for the growth of many pathogens a
Externí odkaz:
https://doaj.org/article/866c6fb23b9740298ef45e53988bde41
Autor:
Giovanni Mergoni, Maddalena Manfredi, Pio Bertani, Tecla Ciociola, Stefania Conti, Laura Giovati
Publikováno v:
Antibiotics, Vol 10, Iss 10, p 1220 (2021)
Enterococcus faecalis is a common cause of biofilm-associated opportunistic infections, which are often difficult to treat. The formation of E. faecalis biofilms on the dentinal walls of the root canal is frequently the cause of endodontic treatment
Externí odkaz:
https://doaj.org/article/e73c6bb1713b4c3f8e31304dd12f0cc1
Publikováno v:
Toxins, Vol 13, Iss 9, p 655 (2021)
Possible implications and applications of the yeast killer phenomenon in the fight against infectious diseases are reviewed, with particular reference to some wide-spectrum killer toxins (KTs) produced by Wickerhamomyces anomalus and other related sp
Externí odkaz:
https://doaj.org/article/ead0bab2177c4dcc8c8ac0246db565ae
Autor:
Paola Di Fermo, Tecla Ciociola, Silvia Di Lodovico, Simonetta D’Ercole, Morena Petrini, Laura Giovati, Stefania Conti, Mara Di Giulio, Luigina Cellini
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1779 (2021)
Chronic wound infections represent an important health problem due to the reduced response to antimicrobial treatment of the pathogens organized in structured biofilms. This study investigated the effects of the previously described antifungal peptid
Externí odkaz:
https://doaj.org/article/64407e9d5da74915b7b4bfc823ab6b7f
Autor:
Luciano Polonelli, Tecla Ciociola, Martina Sperindè, Laura Giovati, Tiziana D’Adda, Serena Galati, Luiz R. Travassos, Walter Magliani, Stefania Conti
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Evidence from previous works disclosed the antimicrobial, antiviral, anti-tumour and/or immunomodulatory activity exerted, through different mechanisms of action, by peptides expressed in the complementarity-determining regions or even in th
Externí odkaz:
https://doaj.org/article/353538c1f54249c5af512a70da48e7df
Autor:
Tecla Ciociola, Walter Magliani, Tiziano De Simone, Thelma A. Pertinhez, Stefania Conti, Giorgio Cozza, Oriano Marin, Laura Giovati
Publikováno v:
Journal of Fungi, Vol 7, Iss 6, p 439 (2021)
It has been previously demonstrated that synthetic antibody-derived peptides could exert a significant activity in vitro, ex vivo, and/or in vivo against microorganisms and viruses, as well as immunomodulatory effects through the activation of immune
Externí odkaz:
https://doaj.org/article/13726d555c8d429f8814478968369ca8
Autor:
Tecla Ciociola, Thelma A. Pertinhez, Tiziano De Simone, Walter Magliani, Elena Ferrari, Silvana Belletti, Tiziana D’Adda, Stefania Conti, Laura Giovati
Publikováno v:
Journal of Fungi, Vol 7, Iss 2, p 129 (2021)
The previously described decapeptide AKVTMTCSAS (killer peptide, KP), derived from the variable region of a recombinant yeast killer toxin-like anti-idiotypic antibody, proved to exert a variety of antimicrobial, antiviral, and immunomodulatory activ
Externí odkaz:
https://doaj.org/article/fefd92844c9648aaa38089eca8acfdc9