Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Laura, Czech"'
Autor:
Laura Czech, Christopher-Nils Mais, Hanna Kratzat, Pinku Sarmah, Pietro Giammarinaro, Sven-Andreas Freibert, Hanna Folke Esser, Joanna Musial, Otto Berninghausen, Wieland Steinchen, Roland Beckmann, Hans-Georg Koch, Gert Bange
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Bacterial responses to nutrient limitation and other stress conditions are often modulated by the nucleotide-based second messenger (p)ppGpp. Here, the authors show that (p)ppGpp inhibits the SRP membrane-protein insertion and secretion pathway by bi
Externí odkaz:
https://doaj.org/article/61ed31ca782f463ca798cb2a7dd3a7ad
Autor:
Fabio Lino Gratani, Till Englert, Payal Nashier, Peter Sass, Laura Czech, Niels Neumann, Sofia Doello, Petra Mann, Rudolf Blobelt, Siegfried Alberti, Karl Forchhammer, Gert Bange, Katharina Höfer, Boris Macek
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT Protein Ser/Thr kinases are posttranslational regulators of key molecular processes in bacteria, such as cell division and antibiotic tolerance. Here, we characterize the E. coli toxin YjjJ (HipH), a putative protein kinase annotated as a me
Externí odkaz:
https://doaj.org/article/5b8a0781d8dc481192c162ec248bb915
Autor:
Alexandra A. Richter, Christopher-Nils Mais, Laura Czech, Kyra Geyer, Astrid Hoeppner, Sander H. J. Smits, Tobias J. Erb, Gert Bange, Erhard Bremer
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of compatible solutes. Ectoine is a prominent member of these types of stress protectants and is produced via an evolutionarily conserved biosynthetic pathway beginnin
Externí odkaz:
https://doaj.org/article/2a7437065e37451c9b031a2d68f60425
Autor:
Laura Czech, Sarah Wilcken, Oliver Czech, Uwe Linne, Jarryd Brauner, Sander H. J. Smits, Erwin A. Galinski, Erhard Bremer
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Extant enzymes are not only highly efficient biocatalysts for a single, or a group of chemically closely related substrates but often have retained, as a mark of their evolutionary history, a certain degree of substrate ambiguity. We have exploited t
Externí odkaz:
https://doaj.org/article/243ff50718c04e6dbd2104f4b32a3a6e
Autor:
Laura Czech, Erhard Bremer
Publikováno v:
PLoS Biology, Vol 16, Iss 2, p e2005163 (2018)
The cellular adjustment of Bacteria and Archaea to high-salinity habitats is well studied and has generally been classified into one of two strategies. These are to accumulate high levels either of ions (the "salt-in" strategy) or of physiologically
Externí odkaz:
https://doaj.org/article/7d25603a895a4d1b880141516f4c723a
Autor:
Yi‐Ming Shi, Jan J. Crames, Laura Czech, Kenan A. J. Bozhüyük, Yan‐Ni Shi, Merle Hirschmann, Stefanie Lamberth, Peter Claus, Nicole Paczia, Christian Rückert, Jörn Kalinowski, Gert Bange, Helge B. Bode
Publikováno v:
Angew Chem Int Ed Engl
Angew Chem Int Ed
Angew Chem Int Ed
Benzoxazolinate is a rare bis-heterocyclic moiety that interacts with proteins and DNA and confers extraordinary bioactivities on natural products, such as C-1027. However, the biosynthetic gene responsible for the key cyclization step of benzoxazoli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2153ac05f1058eb653b781766675d0bf
https://doi.org/10.1002/anie.202206106
https://doi.org/10.1002/anie.202206106
Autor:
Katharina Kohm, Ekaterina Jalomo-Khayrova, Syamantak Basu, Wieland Steinchen, Gert Bange, Robert Hertel, Fabian M. Commichau, Laura Czech
Prophages need to tightly control their lifestyle to either be maintained within the host genome or enter the lytic cycle. The SPβ prophage present in the genome ofBacillus subtilis168 was recently shown to possess anarbitriumsystem defining its rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a7761ce0708fa4cf79c9a7c4138fa6
https://doi.org/10.1101/2022.10.21.513154
https://doi.org/10.1101/2022.10.21.513154
Publikováno v:
Environmental microbiologyREFERENCES. 24(11)
Ectoine and its derivative hydroxyectoine are widely synthesized or imported by bacteria to fend off the detrimental effects of high osmolarity on cellular hydration and growth. Genes that are connected to a particular physiological process are often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d1a66589e439e1bafc9373cc7aa461
https://pubmed.ncbi.nlm.nih.gov/36104950
https://pubmed.ncbi.nlm.nih.gov/36104950
Publikováno v:
BIOspektrum. 26:572-576
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea31ea8660151d5ebea7321c9f5ed30
https://doi.org/10.1007/s12268-020-1442-y
https://doi.org/10.1007/s12268-020-1442-y
Autor:
Laura Czech, Florian Altegoer, Christopher-Nils Mais, Andreas Seubert, Lucas Hermann, Erhard Bremer, Alexandra A. Richter, Gert Bange, Isa Wernersbach
Publikováno v:
'Journal of Biological Chemistry ', vol: 295, pages: 9087-9104 (2020)
J Biol Chem
J Biol Chem
When faced with increased osmolarity in the environment, many bacterial cells accumulate the compatible solute ectoine and its derivative 5-hydroxyectoine. Both compounds are not only potent osmostress protectants, but also serve as effective chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174e81fba4788c6665b8f186ec480a3d
https://doi.org/10.1074/jbc.ra120.012722
https://doi.org/10.1074/jbc.ra120.012722