Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura, Courtois"'
Autor:
Nadège Gruel, Chloé Quignot, Laëtitia Lesage, Sophie El Zein, Sylvie Bonvalot, Dimitri Tzanis, Khadija Ait Rais, Fabien Quinquis, Bastien Manciot, Julien Vibert, Nadine El Tannir, Ahmed Dahmani, Héloïse Derrien, Didier Decaudin, Ivan Bièche, Laura Courtois, Odette Mariani, Laëtitia K. Linares, Laurie Gayte, Sylvain Baulande, Joshua J. Waterfall, Olivier Delattre, Gaëlle Pierron, Sarah Watson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Dedifferentiated liposarcoma (DDLPS) is the most frequent high-grade soft tissue sarcoma subtype. It is characterized by a component of undifferentiated tumor cells coexisting with a component of well-differentiated adipocytic tumor cells. B
Externí odkaz:
https://doaj.org/article/9071f50c747241d985e7d638e844b164
Autor:
Petra ter Brugge, Sarah C. Moser, Ivan Bièche, Petra Kristel, Sabrina Ibadioune, Alexandre Eeckhoutte, Roebi de Bruijn, Eline van der Burg, Catrin Lutz, Stefano Annunziato, Julian de Ruiter, Julien Masliah Planchon, Sophie Vacher, Laura Courtois, Rania El-Botty, Ahmed Dahmani, Elodie Montaudon, Ludivine Morisset, Laura Sourd, Léa Huguet, Heloise Derrien, Fariba Nemati, Sophie Chateau-Joubert, Thibaut Larcher, Anne Salomon, Didier Decaudin, Fabien Reyal, Florence Coussy, Tatiana Popova, Jelle Wesseling, Marc-Henri Stern, Jos Jonkers, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Homologous recombination deficiency is linked with platinum-based chemotherapy response in triple-negative breast cancer (TNBC) but methods to clinically identify these patients are lacking. Here, using patient-derived xenografts of TNBC the authors
Externí odkaz:
https://doaj.org/article/45c67b1c1e0a4a2998d04e87b0b265a7
Autor:
Karina D. Rysenkova, Julia Gaboriaud, Artem I. Fokin, Raphaëlle Toubiana, Alexandre Bense, Camil Mirdass, Mélissa Jin, Minh Chau N. Ho, Elizabeth Glading, Sophie Vacher, Laura Courtois, Ivan Bièche, Alexis M. Gautreau
Publikováno v:
Cells, Vol 13, Iss 10, p 876 (2024)
Breast cancer develops upon sequential acquisition of driver mutations in mammary epithelial cells; however, how these mutations collaborate to transform normal cells remains unclear in most cases. We aimed to reconstitute this process in a particula
Externí odkaz:
https://doaj.org/article/05fe3e22aa2c4c49b708a8d10c872ace
Autor:
Juliette Mainguené, Sophie Vacher, Maud Kamal, Abderaouf Hamza, Julien Masliah‐Planchon, Sylvain Baulande, Sabrina Ibadioune, Edith Borcoman, Wulfran Cacheux, Valentin Calugaru, Laura Courtois, Carole Crozes, Marc Deloger, Elodie Girard, Jean‐Pierre Delord, Antoine Dubray‐Vautrin, Linda Larbi Chérif, Celia Dupain, Emmanuelle Jeannot, Jerzy Klijanienko, Sonia Lameiras, Charlotte Lecerf, Anouchka Modesto, Alain Nicolas, Roman Rouzier, Esma Saada‐Bouzid, Pierre Saintigny, Anne Sudaka, Nicolas Servant, Christophe Le Tourneau, Ivan Bièche
Publikováno v:
Molecular Oncology, Vol 16, Iss 16, Pp 3001-3016 (2022)
A prevalence of around 26% of human papillomavirus (HPV) in head and neck squamous cell carcinoma (HNSCC) has been previously reported. HPV induced oncogenesis mainly involving E6 and E7 viral oncoproteins. In some cases, HPV viral DNA has been detec
Externí odkaz:
https://doaj.org/article/d06dd36b1af84cd3acb67648ff2cbc2c
Autor:
Thibault Passeri, Ahmed Dahmani, Julien Masliah-Planchon, Rania El Botty, Laura Courtois, Sophie Vacher, Elisabetta Marangoni, Fariba Nemati, Sergio Roman-Roman, Homa Adle-Biassette, Hamid Mammar, Sébastien Froelich, Ivan Bièche, Didier Decaudin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundManagement of advanced chordomas remains delicate considering their insensitivity to chemotherapy. Homozygous deletion of the regulatory gene CDKN2A has been described as the most frequent genetic alteration in chordomas and may be consider
Externí odkaz:
https://doaj.org/article/95c1db51b43d4b9c9237e235561b686d
Autor:
Artem I. Fokin, Arthur Boutillon, John James, Laura Courtois, Sophie Vacher, Gleb Simanov, Yanan Wang, Anna Polesskaya, Ivan Bièche, Nicolas B. David, Alexis M. Gautreau
The Rac1-WAVE-Arp2/3 pathway pushes the plasma membrane by polymerizing branched actin at the cell cortex and thereby powering membrane protrusions that mediate cell migration. Here, using knock-down (KD) or knock-out (KO), we combine the inactivatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45a4d9bbd288021b029e490dbc74ef1c
https://doi.org/10.1101/2023.05.13.540631
https://doi.org/10.1101/2023.05.13.540631
Autor:
Grégoire Marret, Constance Lamy, Sophie Vacher, Mathieu Séné, Ladidi Ahmanache, Laura Courtois, Zakhia El Beiano, Jerzy Klijanienko, Charlotte Martinat, Nicolas Servant, Choumouss Kamoun, Linda Larbi Chérif, Thierry Bronzini, Cédric Balsat, Jean-François Laes, Aubray Prévot, Sébastien Sauvage, Maxime Lienard, Emmanuel Martin, Bérengère Genin, Nathalie Badois, Maria Lesnik, Antoine Dubray-Vautrin, Olivier Choussy, Wahib Ghanem, Rabah Taouachi, Julien Masliah Planchon, Ivan Bièche, Maud Kamal, Christophe Le Tourneau
Publikováno v:
Cancer Research. 83:3363-3363
Introduction: Cell-free tumor DNA (ctDNA) is an emerging biomarker in head and neck squamous cell carcinoma (HNSCC) for disease staging, patients’ recurrence risk stratification and early detection of relapse. We aimed to compare variants identifie
Autor:
Marc, Hilmi, Cindy, Neuzillet, Jérémie H, Lefèvre, Magali, Svrcek, Sophie, Vacher, Leonor, Benhaim, Peggy, Dartigues, Emmanuelle, Samalin, Julien, Lazartigues, Jean-François, Emile, Eugénie, Rigault, Nathalie, Rioux-Leclercq, Christelle, de La Fouchardière, David, Tougeron, Wulfran, Cacheux, Pascale, Mariani, Laura, Courtois, Matthieu, Delaye, Virginie, Dangles-Marie, Astrid, Lièvre, Ivan, Bieche
Publikováno v:
Anticancer research. 41(11)
Per literature, patients with epidermal growth factor receptor (EGFR) exon-20 insertions respond poorly to tyrosine kinase inhibitors (TKIs). This study analyzed real-world data to examine the prognostic and predictive value of these mutations.We con