Srf controls satellite cell fusion through the maintenance of actin architecture

Autor: Ulduz Faradova, Laura Collard, Stéphane Vassilopoulos, Emilie Schol, Jean François Decaux, Alessandra Pincini, Aikaterini Papaefthymiou, Athanassia Sotiropoulos, Chiara Noviello, Voahangy Randrianarison-Huetz, Pascal Maire, Gaëlle Herledan

Publikováno v: Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2018, 217 (2), pp.685-700. ⟨10.1083/jcb.201705130⟩
The Journal of Cell Biology
Journal of Cell Biology, 2018, 217 (2), pp.685-700. ⟨10.1083/jcb.201705130⟩

This work describes a crucial role for the transcription factor Srf and F-actin scaffold to drive muscle stem cell fusion in vitro and in vivo and provides evidence of how actin cytoskeleton architecture affects myoblast fusion in vertebrates.
S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff832032dc77c16077073c35ef05cfb
https://hal.archives-ouvertes.fr/hal-02397529

Nuclear actin and myocardin-related transcription factors control disuse muscle atrophy through regulation of Srf activity

Autor: Laura, Collard, Gaëlle, Herledan, Alessandra, Pincini, Aline, Guerci, Voahangy, Randrianarison-Huetz, Athanassia, Sotiropoulos

Publikováno v: Journal of cell science. 127(Pt 24)

Skeletal muscle atrophy is a debilitating process that is associated with a wide variety of conditions including inactivity, disease and aging. Here, we demonstrate that the actin, myocardin-related transcription factors and serum response factor (ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd7ad66100b053d1ee74aea2db31567e
https://pubmed.ncbi.nlm.nih.gov/25344251

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

Autor: Nicolas Cagnard, Luis Garcia, Athanassia Sotiropoulos, Guillaume Précigout, Maryline Favier, Dany Graindorge, David Tuil, Laura Collard, Sabrina Batonnet-Pichon, Charlotte Lahoute, Sophie Hébrard, Dominique Daegelen, Aline Guerci

Publikováno v: Cell Metabolism. (1):25-37

SummaryAdult skeletal muscles adapt their fiber size to workload. We show that serum response factor (Srf) is required for satellite cell-mediated hypertrophic muscle growth. Deletion of Srf from myofibers and not satellite cells blunts overload-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff4f82518c5a888fa44074a582bc818