Phosphorylation of the Hepatitis B Virus Large Envelope Protein

Autor: Marie-Laure Fogeron, Lauriane Lecoq, Laura Cole, Roland Montserret, Guillaume David, Adeline Page, Frédéric Delolme, Michael Nassal, Anja Böckmann

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2022)

We here establish the phosphorylation sites in the human hepatitis B virus (HBV) large envelope protein (L). L is involved in several functionally important interactions in the viral life cycle, including with the HBV cellular receptor, HBV capsid, H

Externí odkaz: https://doaj.org/article/fe3bd340ead241f8876af355835756df

Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications

Autor: Nadide Altincekic, Sophie Marianne Korn, Nusrat Shahin Qureshi, Marie Dujardin, Martí Ninot-Pedrosa, Rupert Abele, Marie Jose Abi Saad, Caterina Alfano, Fabio C. L. Almeida, Islam Alshamleh, Gisele Cardoso de Amorim, Thomas K. Anderson, Cristiane D. Anobom, Chelsea Anorma, Jasleen Kaur Bains, Adriaan Bax, Martin Blackledge, Julius Blechar, Anja Böckmann, Louis Brigandat, Anna Bula, Matthias Bütikofer, Aldo R. Camacho-Zarco, Teresa Carlomagno, Icaro Putinhon Caruso, Betül Ceylan, Apirat Chaikuad, Feixia Chu, Laura Cole, Marquise G. Crosby, Vanessa de Jesus, Karthikeyan Dhamotharan, Isabella C. Felli, Jan Ferner, Yanick Fleischmann, Marie-Laure Fogeron, Nikolaos K. Fourkiotis, Christin Fuks, Boris Fürtig, Angelo Gallo, Santosh L. Gande, Juan Atilio Gerez, Dhiman Ghosh, Francisco Gomes-Neto, Oksana Gorbatyuk, Serafima Guseva, Carolin Hacker, Sabine Häfner, Bing Hao, Bruno Hargittay, K. Henzler-Wildman, Jeffrey C. Hoch, Katharina F. Hohmann, Marie T. Hutchison, Kristaps Jaudzems, Katarina Jović, Janina Kaderli, Gints Kalniņš, Iveta Kaņepe, Robert N. Kirchdoerfer, John Kirkpatrick, Stefan Knapp, Robin Krishnathas, Felicitas Kutz, Susanne zur Lage, Roderick Lambertz, Andras Lang, Douglas Laurents, Lauriane Lecoq, Verena Linhard, Frank Löhr, Anas Malki, Luiza Mamigonian Bessa, Rachel W. Martin, Tobias Matzel, Damien Maurin, Seth W. McNutt, Nathane Cunha Mebus-Antunes, Beat H. Meier, Nathalie Meiser, Miguel Mompeán, Elisa Monaca, Roland Montserret, Laura Mariño Perez, Celine Moser, Claudia Muhle-Goll, Thais Cristtina Neves-Martins, Xiamonin Ni, Brenna Norton-Baker, Roberta Pierattelli, Letizia Pontoriero, Yulia Pustovalova, Oliver Ohlenschläger, Julien Orts, Andrea T. Da Poian, Dennis J. Pyper, Christian Richter, Roland Riek, Chad M. Rienstra, Angus Robertson, Anderson S. Pinheiro, Raffaele Sabbatella, Nicola Salvi, Krishna Saxena, Linda Schulte, Marco Schiavina, Harald Schwalbe, Mara Silber, Marcius da Silva Almeida, Marc A. Sprague-Piercy, Georgios A. Spyroulias, Sridhar Sreeramulu, Jan-Niklas Tants, Kaspars Tārs, Felix Torres, Sabrina Töws, Miguel Á. Treviño, Sven Trucks, Aikaterini C. Tsika, Krisztina Varga, Ying Wang, Marco E. Weber, Julia E. Weigand, Christoph Wiedemann, Julia Wirmer-Bartoschek, Maria Alexandra Wirtz Martin, Johannes Zehnder, Martin Hengesbach, Andreas Schlundt

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects. The international COVID19-NMR consortium

Externí odkaz: https://doaj.org/article/201170fa84b8450e9b468d9fb4480774

Forensic Discrimination of Differentially Sourced Animal Blood Using a Bottom-Up Proteomics Based MALDI MS Approach

Autor: Katie Kennedy, Laura Cole, Matthias Witt, Mark Sealey, Simona Francese

Publikováno v: Molecules, Vol 27, Iss 7, p 2039 (2022)

Recently published work has reported the development and application of a bottom-up proteomic approach to distinguish between human and animal blood (down to animal species level), by rapid screening using Matrix Assisted Laser Desorption Ionisation

Externí odkaz: https://doaj.org/article/d6c07d0fe22b4c4f9a99475eb0806121

Do NSm virulence factors in the Bunyavirales order originate from Gn gene duplication?

Autor: Victor Lefebvre, Ravy Leon Foun Lin, Laura Cole, François-Loïc Cosset, Marie-Laure Fogeron, Anja Böckmann

Several viral members of the large viral order of the Bunyavirales carry a NSm protein that acts as a virulence factor. Here we used AlphaFold to predict the structures of these NSm proteins and surprisingly found that the cytosolic domain of theNair

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bf2df699916999216a1b6755213c688
https://doi.org/10.1101/2023.04.13.536692

A multi-omics analysis of glioma chemoresistance using a hybrid microphysiological model of glioblastoma

Autor: Shahla Shojaei, João Basso, Meitham Amereh, Javad Alizadeh, Tania Dehesh, Simone De Silva Rosa, Courtney Clark, Misha Hassan, Mateuz Tomczyk, Laura Cole, Grant Hatch, Vern Dolinsky, Chris Pasco, David Schibli, Sanjiv Dhingra, Abhay Srivastava, Amir Ravandi, Rui Vitorino, Saeid Ghavami, Mohsen Akbari

Chemoresistance is a major clinical challenge in the management of glioblastoma (GBM) Temozolomide (TMZ) is the chemotherapeutic drug of choice for GBM; however, the therapeutic effect of TMZ is limited due to the development of resistance. Recapitul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd0c65d247c7fabb35433de79340dda4
https://doi.org/10.1101/2022.10.29.514383