Efficient stabilization of therapeutic hepatitis B vaccine components by amino-acid formulation maintains its potential to break immune tolerance.

Autor: Sacherl J; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Kosinska AD; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany., Kemter K; LEUKOCARE AG, Martinsried, Germany., Kächele M; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Laumen SC; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Kerth HA; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany., Öz EA; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Wolff LS; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Su J; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany., Essbauer S; Bundeswehr Institute of Microbiology, Munich, Germany., Sutter G; Institute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany., Scholz M; LEUKOCARE AG, Martinsried, Germany., Singethan K; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany.; Bundeswehr Institute of Microbiology, Munich, Germany., Altrichter J; LEUKOCARE AG, Martinsried, Germany., Protzer U; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, Munich, Germany.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2022 Oct 13; Vol. 5 (2), pp. 100603. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2023).