Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes.

Autor: Kossila, Maija, Sinkovic, Marina, Karkkainen, Paivi, Laukkanen, Mikko O., Miettinen, Raija, Rissanen, Johanna, Kekalainen, Paivi, Kuusisto, Johanna, Yla-Herttuala, Seppo, Laakso, Markku, Kossila, M, Sinkovic, M, Kärkkäinen, P, Laukkanen, M O, Miettinen, R, Rissanen, J, Kekäläinen, P, Kuusisto, J, Ylä-Herttuala, S, Laakso, M

Publikováno v: Diabetes; Oct2000, Vol. 49 Issue 10, p1740-1743, 4p, 2 Charts, 1 Graph

Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation

Autor: Laukkanen, M. O., Lehtolainen, P., Turunen, P., Aittomaki, S., Oikari, P., Marklund, S. L., Yla-Herttuala, S.

Publikováno v: Gene; 2000, Vol. 254 Issue: 1 p173-179, 7p

Sonic Hedgehog in SCLC

Autor: Laukkanen, M. O., Gutkind, J. S., MARIADOMENICA CASTELLONE

Publikováno v: Scopus-Elsevier
Aging (Albany, N.Y. Online) 7 (2015): 605–606.
info:cnr-pdr/source/autori:Laukkanen M.O.; Gutkind J.S.; Castellone M.D./titolo:Sonic Hedgehog in SCLC/doi:/rivista:Aging (Albany, N.Y. Online)/anno:2015/pagina_da:605/pagina_a:606/intervallo_pagine:605–606/volume:7

The Hedgehog (Hh) signal transduction pathway has been discovered as a central regulator of embryonic development, tissue maintenance and repair [1]. Moreover, several recent evidences have highlighted its key function in tumorigenesis [2]. In some f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d99e19abef9e1be6fb78c3529bd6b0e
http://www.scopus.com/inward/record.url?eid=2-s2.0-84943384965&partnerID=MN8TOARS

Extracellular Superoxide Dismutase Is a Growth Regulatory Mediator of Tissue Injury Recovery

Autor: Merja Haaparanta-Solin, Maria Domenica Castellone, Juha P. Laurila, Päivi Marjamäki, Mikko O. Laukkanen, Tove J. Grönroos, Lilja E. Laatikainen, Antonio Curcio, Massimo Santoro, Satu Martikainen

Publikováno v: Molecular Therapy. 17:448-454

Extracellular superoxide dismutase (SOD3) gene therapy has been shown to attenuate tissue damages and to improve the recovery of the tissue injuries, but the cellular events delivering the therapeutic response of the enzyme are not well defined. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f80dfc4e6b8c422e780a3294c3249cc
https://doi.org/10.1038/mt.2008.282

SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a

Autor: Massimo Santoro, Lilja E. Laatikainen, Maria Domenica Castellone, Juha P. Laurila, Mikko O. Laukkanen, Mariarosaria Incoronato

Publikováno v: PLoS ONE
PLoS ONE, Vol 6, Iss 8, p e24456 (2011)
PloS one 6 (2011). doi:10.1371/journal.pone.0024456
info:cnr-pdr/source/autori:Laatikainen, LE [ 1 ] ; Incoronato, M [ 2 ] ; Castellone, MD [ 3 ] ; Laurila, JP [ 1 ] ; Santoro, M [ 3 ] ; Laukkanen, MO [ 1,2]/titolo:SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1%2F2, Akt, and FoxO3a./doi:10.1371%2Fjournal.pone.0024456/rivista:PloS one/anno:2011/pagina_da:/pagina_a:/intervallo_pagine:/volume:6

BackgroundExtracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9151e73325adc1932244060875914a3d
http://europepmc.org/articles/PMC3164207