Analysis of Wilms' tumor protein 1 specific TCR repertoire in AML patients uncovers higher diversity in patients in remission than in relapsed.

Autor: Gielis S; Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Biomedical Informatics Research Network Antwerp (Biomina), University of Antwerp, Antwerp, Belgium., Flumens D; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium., van der Heijden S; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium., Versteven M; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium., De Reu H; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium., Bartholomeus E; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Belgium.; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Belgium., Schippers J; Genetics, Pharmacology and Physiopathology of Heart, Blood Vessels and Skeleton (GENCOR) department, University of Antwerp, Edegem, Belgium., Campillo-Davo D; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium., Berneman ZN; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.; Center for Cell Therapy & Regenerative Medicine (CCRG), Antwerp University Hospital, Edegem, Belgium., Anguille S; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.; Center for Cell Therapy & Regenerative Medicine (CCRG), Antwerp University Hospital, Edegem, Belgium.; Division of Hematology, Antwerp University Hospital, Edegem, Belgium., Smits E; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Center for Oncological Research (CORE), Integrated Personalized & Precision Oncology Network (IPPON), University of Antwerp, Wilrijk, Belgium.; Center for Cell Therapy & Regenerative Medicine (CCRG), Antwerp University Hospital, Edegem, Belgium., Ogunjimi B; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Department of Paediatrics, Antwerp University Hospital, Edegem, Belgium.; Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Belgium.; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute, University of Antwerp, Wilrijk, Belgium., Lion E; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Laboratory of Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO), Faculty of Medicine and Health Sciences, University of Antwerp, Edegem, Belgium.; Center for Cell Therapy & Regenerative Medicine (CCRG), Antwerp University Hospital, Edegem, Belgium., Laukens K; Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium.; Biomedical Informatics Research Network Antwerp (Biomina), University of Antwerp, Antwerp, Belgium., Meysman P; Adrem Data Lab, Department of Computer Science, University of Antwerp, Antwerp, Belgium. pieter.meysman@uantwerpen.be.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing (AUDACIS), University of Antwerp, Antwerp, Belgium. pieter.meysman@uantwerpen.be.; Biomedical Informatics Research Network Antwerp (Biomina), University of Antwerp, Antwerp, Belgium. pieter.meysman@uantwerpen.be.

Publikováno v: Annals of hematology [Ann Hematol] 2024 Sep 11. Date of Electronic Publication: 2024 Sep 11.

Nanopore sequencing for Mycobacterium tuberculosis: a critical review of the literature, new developments and future opportunities

Autor: Dippenaar, A., Goossens, S.N., Grobbelaar, M., Oostvogels, S., Cuypers, B., Laukens, K., Meehan, Conor J., Warren, R.M., van Rie, A.

Yes
The next-generation short-read sequencing technologies that generate comprehensive, whole-genome data with single-nucleotide resolution have already advanced tuberculosis diagnosis, treatment, surveillance and source investigation. Their hig

Externí odkaz: http://hdl.handle.net/10454/18521

Correction to "Semisupervised Learning to Boost hERG, Nav1.5, and Cav1.2 Cardiac Ion Channel Toxicity Prediction by Mining a Large Unlabeled Small Molecule Data Set".

Autor: Arab I, Laukens K, Bittremieux W

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2024 Nov 26. Date of Electronic Publication: 2024 Nov 26.

Immune-based Machine learning Prediction of Diagnosis and Illness State in Schizophrenia and Bipolar Disorder.

Autor: Skorobogatov K; Scientific Initiative for Neuropsychiatric and Psychopharmacological Studies (SINAPS), University Psychiatric Hospital Campus Duffel (UPCD), Rooienberg 19, 2570 Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Campus Drie Eiken, S.003, Universiteitsplein 1, 2610 Wilrijk, Belgium. Electronic address: katrien.skorobogatov@uantwerpen.be., De Picker L; Scientific Initiative for Neuropsychiatric and Psychopharmacological Studies (SINAPS), University Psychiatric Hospital Campus Duffel (UPCD), Rooienberg 19, 2570 Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Campus Drie Eiken, S.003, Universiteitsplein 1, 2610 Wilrijk, Belgium., Wu CL; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Foiselle M; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Richard JR; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Boukouaci W; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Bouassida J; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Laukens K; Biomedical Informatics Research Center Antwerp (BIOMINA), University of Antwerp, Campus Middelheim, M.G.111, Middelheimlaan 1, 2020 Antwerp, Belgium; Department of Mathematics and Computer Science, University of Antwerp, Campus Middelheim, M.G.105, Antwerp, Belgium., Meysman P; Biomedical Informatics Research Center Antwerp (BIOMINA), University of Antwerp, Campus Middelheim, M.G.111, Middelheimlaan 1, 2020 Antwerp, Belgium; Department of Mathematics and Computer Science, University of Antwerp, Campus Middelheim, M.G.105, Antwerp, Belgium., le Corvoisier P; Inserm, Centre d'Investigation Clinique 1430, AP-HP, Hôpital Henri Mondor, Université Paris Est Créteil, Faculté de Médecine de Créteil 8, Rue Du Général Sarrail 94010, Créteil, France., Barau C; Plateforme de Ressources Biologiques, Hôpital Henri Mondor, 51 Avenue due Maréchal de Lattre de Tassigny, 94010 Créteil, France., Morrens M; Scientific Initiative for Neuropsychiatric and Psychopharmacological Studies (SINAPS), University Psychiatric Hospital Campus Duffel (UPCD), Rooienberg 19, 2570 Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Campus Drie Eiken, S.003, Universiteitsplein 1, 2610 Wilrijk, Belgium., Tamouza R; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France., Leboyer M; Université Paris Est Créteil (UPEC), Inserm U955, IMRB Translational Neuropsychiatry Laboratory, AP-HP, Hôpitaux Universitaires H Mondor, DMU IMPACT, FHU ADAPT, Fondation FondaMental, Créteil, France.

Publikováno v: Brain, behavior, and immunity [Brain Behav Immun] 2024 Nov; Vol. 122, pp. 422-432. Date of Electronic Publication: 2024 Aug 14.

Unraveling the Immune Signature of Herpes Zoster: Insights Into the Pathophysiology and Human Leukocyte Antigen Risk Profile.

Autor: Vandoren R; Adrem Data Lab, Department of Computer Science, University of Antwerp.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Biomedical Informatics Research Network Antwerp., Boeren M; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Laboratory of Microbiology, Parasitology and Hygiene and Infla-Med Center of Excellence.; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute.; Antwerp Center for Translational Immunology and Virology, Vaccine and Infectious Disease Institute.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute., Schippers J; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Antwerp Center for Translational Immunology and Virology, Vaccine and Infectious Disease Institute.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute., Bartholomeus E; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Antwerp Center for Translational Immunology and Virology, Vaccine and Infectious Disease Institute.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute., Mullan K; Adrem Data Lab, Department of Computer Science, University of Antwerp.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Biomedical Informatics Research Network Antwerp., Michels N; Department of Family Medicine and Population Health, Center for General Practice/Family Medicine, University of Antwerp., Aerts O; Department of Dermatology, Antwerp University Hospital and University of Antwerp., Leysen J; Department of Dermatology, Antwerp University Hospital and University of Antwerp., Bervoets A; Department of Dermatology, Antwerp University Hospital and University of Antwerp., Lambert J; Department of Dermatology, Antwerp University Hospital and University of Antwerp., Leuridan E; Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp., Wens J; Department of Family Medicine and Population Health, Center for General Practice/Family Medicine, University of Antwerp., Peeters K; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Antwerp Center for Translational Immunology and Virology, Vaccine and Infectious Disease Institute.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute., Emonds MP; Histocompatibility and Immunogenetic Laboratory, Rode Kruis-Vlaanderen, Mechelen., Jansens H; Department of Clinical Microbiology, Antwerp University Hospital, Belgium., Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U1163, Necker Hospital for Sick Children, Paris.; Imagine Institute, Paris Cité University, France.; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University.; Howard Hughes Medical Institute, New York, New York.; Department of Pediatrics, Necker Hospital for Sick Children, Paris., Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U1163, Necker Hospital for Sick Children, Paris.; Imagine Institute, Paris Cité University, France.; St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistante Publique-Hôpitaux de Paris, France., Suls A; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Medical Genetics, University of Antwerp and Antwerp University Hospital., Van Tendeloo V; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute., Ponsaerts P; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute., Delputte P; Laboratory of Microbiology, Parasitology and Hygiene and Infla-Med Center of Excellence., Ogunjimi B; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Antwerp Center for Translational Immunology and Virology, Vaccine and Infectious Disease Institute.; Centre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute.; Department of Paediatrics, Antwerp University Hospital, Belgium., Laukens K; Adrem Data Lab, Department of Computer Science, University of Antwerp.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Biomedical Informatics Research Network Antwerp., Meysman P; Adrem Data Lab, Department of Computer Science, University of Antwerp.; Antwerp Unit for Data Analysis and Computation in Immunology and Sequencing, University of Antwerp.; Biomedical Informatics Research Network Antwerp.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Sep 23; Vol. 230 (3), pp. 706-715.