Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

Autor: Osborne, Lisa C., Monticelli, Laurel A., Nice, Timothy J., Sutherland, Tara E., Siracusa, Mark C., Hepworth, Matthew R., Tomov, Vesselin T., Kobuley, Dmytro, Tran, Sara V., Bittinger, Kyle, Bailey, Aubrey G., Laughlin, Alice L., Boucher, Jean-Luc, Wherry, E. John, Bushman, Frederic D., Allen, Judith E., Virgin, Herbert W., Artis, David

Publikováno v: Science, 2014 Aug 01. 345(6196), 578-582.

Externí odkaz: http://www.jstor.org/stable/24745232

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Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.

Autor: Osborne LC; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Monticelli LA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Nice TJ; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Sutherland TE; Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK., Siracusa MC; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Hepworth MR; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Medicine, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Tomov VT; Department of Medicine, Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Kobuley D; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Tran SV; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bittinger K; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bailey AG; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Laughlin AL; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Boucher JL; Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Université Paris Descartes, Paris, France., Wherry EJ; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bushman FD; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Allen JE; Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK., Virgin HW; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Artis D; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. dartis@mail.med.upenn.edu.

Publikováno v: Science (New York, N.Y.) [Science] 2014 Aug 01; Vol. 345 (6196), pp. 578-82. Date of Electronic Publication: 2014 Jul 17.