Theoretical study on solute migration and band broadening occurring in pressure-enhanced liquid chromatography.

Autor: Fekete S; Waters Corporation, located in CMU-Rue Michel Servet 1, 1211 Geneva 4, Switzerland. Electronic address: Szabolcs_Fekete@waters.com., Lauber MA; Waters Corporation, 34 Maple Street, Milford MA 01757, USA.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2023 Mar 15; Vol. 1692, pp. 463872. Date of Electronic Publication: 2023 Feb 12.

The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides.

Autor: Lardeux H; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland., Goyon A; Small Molecule Pharmaceutical Sciences, Genentech Inc., DNA Way, South San Francisco, CA 94080, USA., Zhang K; Small Molecule Pharmaceutical Sciences, Genentech Inc., DNA Way, South San Francisco, CA 94080, USA., Nguyen JM; Waters Corporation, 34 Maple Street, Milford, MA 01757, USA., Lauber MA; Waters Corporation, 34 Maple Street, Milford, MA 01757, USA., Guillarme D; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland., D'Atri V; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, Geneva 4 1211, Switzerland. Electronic address: valentina.datri@unige.ch.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2022 Aug 16; Vol. 1677, pp. 463324. Date of Electronic Publication: 2022 Jul 09.

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.

Autor: Liu H; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Iketani S; Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA.; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, 10032, USA., Zask A; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA., Khanizeman N; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Bednarova E; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Forouhar F; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Fowler B; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Hong SJ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA., Mohri H; Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Nair MS; Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Huang Y; Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA., Tay NES; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Lee S; Department of Chemistry, Columbia University, New York, NY, 10027, USA., Karan C; Sulzberger Columbia Genome Center, Columbia University, New York, NY, 10032, USA., Resnick SJ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA.; Medical Scientist Training Program, Columbia University Irving Medical Center, New York, NY, 10032, USA., Quinn C; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Li W; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Shion H; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Xia X; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA., Daniels JD; Department of Pharmacology and Molecular Therapeutics, Columbia University Irving Medical Center, New York, NY, 10032, USA., Bartolo-Cruz M; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA., Farina M; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA.; Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil., Rajbhandari P; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA., Jurtschenko C; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Lauber MA; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., McDonald T; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Stokes ME; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA., Hurst BL; Institute for Antiviral Research, Utah State University, Logan, UT, 84322, USA., Rovis T; Department of Chemistry, Columbia University, New York, NY, 10027, USA. tr2504@columbia.edu., Chavez A; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA. ac4304@cumc.columbia.edu., Ho DD; Aaron Diamond AIDS Research Center, Columbia University Irving Medical Center, New York, NY, 10032, USA. dh2994@cumc.columbia.edu., Stockwell BR; Department of Chemistry, Columbia University, New York, NY, 10027, USA. bstockwell@columbia.edu.; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA. bstockwell@columbia.edu.

Publikováno v: Nature communications [Nat Commun] 2022 Apr 07; Vol. 13 (1), pp. 1891. Date of Electronic Publication: 2022 Apr 07.

Size Exclusion and Ion Exchange Chromatographic Hardware Modified with a Hydrophilic Hybrid Surface.

Autor: Fekete S; Waters Corporation, CMU-Rue Michel Servet 1, 1211 Geneva 4, Switzerland., DeLano M; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States., Harrison AB; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States., Shiner SJ; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States., Belanger JL; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States., Wyndham KD; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States., Lauber MA; Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2022 Feb 22; Vol. 94 (7), pp. 3360-3367. Date of Electronic Publication: 2022 Feb 10.

Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins.

Autor: Navarro-Huerta JA; Department of Analytical Chemistry, Faculty of Chemistry, Universitat de València, C/ Dr. Moliner 50, 46100, Burjassot, Spain., Murisier A; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland., Nguyen JM; Waters Corporation, 34 Maple Street, Milford, MA, 01757-3696, United States., Lauber MA; Waters Corporation, 34 Maple Street, Milford, MA, 01757-3696, United States., Beck A; IRPF, Center of Immunology Pierre Fabre, 5 Avenue Napoléon III, BP 60497, 74160, Saint-Julien-en-Genevois, France., Guillarme D; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland., Fekete S; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland. Electronic address: Szabolcs_Fekete@waters.com.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2021 Nov 08; Vol. 1657, pp. 462568. Date of Electronic Publication: 2021 Sep 22.