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pro vyhledávání: '"Lau K. Vestergaard"'
Autor:
Lau K. Vestergaard, Nicolai S. Mikkelsen, Douglas V. N. P. Oliveira, Tim S. Poulsen, Estrid V. Hoegdall
Publikováno v:
Reports, Vol 6, Iss 2, p 23 (2023)
The implementation of next-generation sequencing (NGS) in clinical oncology has enabled the analysis of multiple cancer-associated genes for diagnostics and treatment purposes. The detection of pathogenic and likely pathogenic mutations is crucial to
Externí odkaz:
https://doaj.org/article/447f0e1a27e94651ad8d5428a50db47d
Autor:
Lau K. Vestergaard, Douglas N. P. Oliveira, Tim S. Poulsen, Claus K. Høgdall, Estrid V. Høgdall
Publikováno v:
Cancers, Vol 13, Iss 20, p 5230 (2021)
The usage of next generation sequencing in combination with targeted gene panels has enforced a better understanding of tumor compositions. The identification of key genomic biomarkers underlying a disease are crucial for diagnosis, prognosis, treatm
Externí odkaz:
https://doaj.org/article/55bc9e163fda495eb69da72ee5cbb429
Publikováno v:
Cancers, Vol 13, Iss 8, p 1751 (2021)
Data analysis has become a crucial aspect in clinical oncology to interpret output from next-generation sequencing-based testing. NGS being able to resolve billions of sequencing reactions in a few days has consequently increased the demand for tools
Externí odkaz:
https://doaj.org/article/3335fcbf71134cb9b6645b6c9ac059f9
Autor:
Tim Svenstrup Poulsen, Douglas N P Oliveira, Lau K Vestergaard, Claus Høgdall, Estrid Høgdall
Publikováno v:
Vestergaard, L K, Oliveira, D N P, Poulsen, T S, Høgdall, C K & Høgdall, E V 2021, ' Oncomine™ Comprehensive Assay v3 vs. Oncomine™ Comprehensive Assay Plus ', Cancers, vol. 13, no. 20, 5230 . https://doi.org/10.3390/cancers13205230
Cancers
Volume 13
Issue 20
Cancers, Vol 13, Iss 5230, p 5230 (2021)
Cancers
Volume 13
Issue 20
Cancers, Vol 13, Iss 5230, p 5230 (2021)
Simple Summary The detection of genetic alterations in cancer is important to obtain knowledge of the underlying mutational tumor composition. Knowing the mutational profile can assist oncologists on tailoring optimal personalized treatments. Moreove
Autor:
Andrea Lenk, Torsten Schultz-Larsen, Erika Isono, Carsten Pedersen, Hans Thordal-Christensen, Kamila Kalinowska, Lau K Vestergaard
Publikováno v:
Schultz-Larsen, T, Lenk, A, Kalinowska, K, Vestergaard, L K, Pedersen, C, Isono, E & Thordal-Christensen, H 2018, ' The AMSH3 ESCRT-III-Associated Deubiquitinase Is Essential for Plant Immunity ', Cell Reports, vol. 25, no. 9, pp. 2329-2338.e5 . https://doi.org/10.1016/j.celrep.2018.11.011
Plant “nucleotide-binding leucine-rich repeat” receptor proteins (NLRs) detect alterations in host targets of pathogen effectors and trigger immune responses. The Arabidopsis thaliana mutant pen1 syp122 displays autoimmunity, and a mutant screen