A machine-learning exploration of the exposome from preconception in early childhood atopic eczema, rhinitis and wheeze development.

Autor: Dong Y; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore. Electronic address: yizhi@nus.edu.sg., Lau HX; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore. Electronic address: lau_hui_xing@sics.a-star.edu.sg., Suaini NHA; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore. Electronic address: Noor_Hidayatul_Suaini@sics.a-star.edu.sg., Kee MZL; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore. Electronic address: Michelle_Kee@sics.a-star.edu.sg., Ooi DSQ; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore. Electronic address: paeosqd@nus.edu.sg., Shek LP; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: paeshekl@nus.edu.sg., Lee BW; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: paeleebw@nus.edu.sg., Godfrey KM; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom; MRC Lifecourse Epidemiology Centre, Faculty of Medicine, University of Southampton, Southampton, United Kingdom. Electronic address: kmg@mrc.soton.ac.uk., Tham EH; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address: elizabeth_tham@nuhs.edu.sg., Ong MEH; Department of Emergency Medicine, Singapore General Hospital, Singapore, Singapore; Health Services and Systems Research, Duke-NUS Graduate Medical School, Singapore, Singapore. Electronic address: marcus.ong@duke-nus.edu.sg., Liu N; Duke-NUS Medical School, National University of Singapore, Singapore; Health Services Research Centre, Singapore Health Services, Singapore, Singapore; Institute of Data Science, National University of Singapore, Singapore. Electronic address: liu.nan@duke-nus.edu.sg., Wong L; School of Computing, National University of Singapore, 13 Computing Drive, Singapore 117417, Singapore. Electronic address: wongls@comp.nus.edu.sg., Tan KH; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital (KKH), Singapore. Electronic address: tan.kok.hian@singhealth.com.sg., Chan JKY; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Reproductive Medicine, KK Women's and Children's Hospital (KKH), Singapore. Electronic address: jerrychan@duke-nus.edu.sg., Yap FKP; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. Electronic address: fabian.yap.k.p@singhealth.com.sg., Chong YS; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore. Electronic address: obgcys@nus.edu.sg., Eriksson JG; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore; Folkhälsan Research Center, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Finland. Electronic address: obgjge@nus.edu.sg., Feng M; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore. Electronic address: ephfm@nus.edu.sg., Loo EXL; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), 30 Medical Drive, Singapore, 117609, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Dean's Office, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: evelyn_loo@sics.a-star.edu.sg.

Publikováno v: Environmental research [Environ Res] 2024 Jun 01; Vol. 250, pp. 118523. Date of Electronic Publication: 2024 Feb 19.

Clinical predictors of wheeze trajectories and associations with allergy in Asian children.

Autor: Lau HX; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chen Z; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Van Bever H; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Tham EH; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Chan YH; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Yap QV; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Goh AEN; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore., Teoh OH; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore., Tan KH; Department of Maternal Fetal Medicine, KKH, Singapore, Singapore., Yap FKP; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore; Duke- National University of Singapore (NUS) Medical School, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Godfrey KM; Faculty of Medicine, School of Human Development and Health, University of Southampton, Southampton, United Kingdom; National Institute for Health Research (NIHR) Southampton Biomedical Research Centre, University Hospital Southampton National Health Service (NHS) Foundation Trust and University of Southampton, Southampton, United Kingdom; Medical Research Council (MRC) Lifecourse Epidemiology Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom., Eriksson JG; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore; Folkhälsan Research Center, Helsinki, Finland; Department of General Practice and Primary Health Care, University of Helsinki, Finland; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and National University Health System, Singapore., Chong YS; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and National University Health System, Singapore., Lee BW; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Shek LP; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore., Loo EXL; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore. Electronic address: evelyn_loo@sics.a-star.edu.sg.

Publikováno v: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2023 Oct; Vol. 131 (4), pp. 466-473.e6. Date of Electronic Publication: 2023 Jul 05.

Comparison of transversus abdominis activation characteristics between healthy and chronic low back pain population during upright functional movement.

Autor: Cai C; Health and Social Sciences Cluster - Physiotherapy, Singapore Institute of Technology, Dover, Singapore.; Ng Teng Fong General Hospital, JurongHealth Campus, National University Health Service, Jurong East, Singapore., Gazali NA; Health and Social Sciences Cluster - Diagnostic Radiography, Singapore Institute of Technology, Dover, Singapore.; SingHealth Group, Sengkang General Hospital, Sengkang, Singapore., Lau HX; Health and Social Sciences Cluster - Physiotherapy, Singapore Institute of Technology, Dover, Singapore., Tan MBC; Health and Social Sciences Cluster - Physiotherapy, Singapore Institute of Technology, Dover, Singapore., Othman EI; Health and Social Sciences Cluster - Diagnostic Radiography, Singapore Institute of Technology, Dover, Singapore., Chan CSQ; Health and Social Sciences Cluster - Diagnostic Radiography, Singapore Institute of Technology, Dover, Singapore., Lim ECW; Health and Social Sciences Cluster - Physiotherapy, Singapore Institute of Technology, Dover, Singapore.

Publikováno v: Journal of back and musculoskeletal rehabilitation [J Back Musculoskelet Rehabil] 2023; Vol. 36 (5), pp. 1075-1086.

Allergic sensitization trajectories to age 8 years in the Singapore GUSTO cohort.

Autor: Lau HX; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore., Chen Z; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chan YH; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tham EH; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Goh AEN; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore., Van Bever H; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Teoh OH; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore., Karnani N; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore., Gluckman PD; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Liggins Institute, University of Auckland, Auckland, New Zealand., Tan KH; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital (KKH), Singapore, Singapore., Yap FKP; Department of Paediatrics, KK Women's and Children's Hospital (KKH), Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Godfrey KM; MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom., Eriksson JG; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland., Chong YS; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Lee BW; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Shek LP; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Loo EXL; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Publikováno v: The World Allergy Organization journal [World Allergy Organ J] 2022 Jul 14; Vol. 15 (7), pp. 100667. Date of Electronic Publication: 2022 Jul 14 (Print Publication: 2022).

Associations Between Eczema and Attention Deficit Hyperactivity Disorder Symptoms in Children.

Autor: Loo EXL; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ooi DSQ; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ong M; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore., Ta LDH; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lau HX; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore., Tay MJY; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yap QV; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Chan YH; Department of Biostatistics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tham EH; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore., Goh AEN; Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Van Bever H; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore., Teoh OH; Respiratory Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Eriksson JG; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Human Potential Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Folkhälsan Research Center, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Chong YS; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Gluckman P; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Liggins Institute, University of Auckland, Auckland, New Zealand., Yap FKP; Duke-NUS Medical School, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Endocrinology Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Karnani N; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore., Xu J; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore., Tan KML; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore., Tan KH; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore., Lee BW; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Kramer M; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Pediatrics and of Epidemiology and Biostatistics, McGill University Faculty of Medicine, Montreal, QC, Canada., Shek LP; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore., Meaney MJ; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Sackler Program for Epigenetics & Psychobiology at McGill University, Montreal, QC, Canada.; Ludmer Centre for Neuroinformatics and Mental Health, McGill University, Montreal, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada., Broekman BFP; Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research, Singapore, Singapore.; Department of Psychiatry, OLVG and Amsterdam UMC, VU University, Amsterdam, Netherlands.

Publikováno v: Frontiers in pediatrics [Front Pediatr] 2022 Mar 30; Vol. 10, pp. 837741. Date of Electronic Publication: 2022 Mar 30 (Print Publication: 2022).