Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Laty G. Thiam"'
Autor:
Laty G. Thiam, Kirsty McHugh, Aboubacar Ba, Rebecca Li, Yicheng Guo, Mariama N. Pouye, Awa Cisse, Dimitra Pipini, Fatoumata Diallo, Seynabou D. Sene, Saurabh D. Patel, Alassane Thiam, Bacary D. Sadio, Alassane Mbengue, Inés Vigan-Womas, Zizhang Sheng, Lawrence Shapiro, Simon J. Draper, Amy K. Bei
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Vaccines to the Plasmodium falciparum reticulocyte binding-like protein homologue 5 (PfRH5) target the blood-stage of the parasite life cycle. PfRH5 has the potential to trigger the production of strain-transcendent antibodies and has proven
Externí odkaz:
https://doaj.org/article/e107ccb140a3481e807421a3633b07ca
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Ex vivo phenotyping of P. falciparum erythrocyte invasion diversity is important in the identification and down selection of potential malaria vaccine targets. However, due to the lack of appropriate laboratory facilities in remote areas of endemic c
Externí odkaz:
https://doaj.org/article/d13bbfce1c274f5cacbe8112859edf24
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundErythrocyte invasion by P. falciparum involves functionally overlapping interactions between the parasite’s ligands and the erythrocyte surface receptors. While some P. falciparum isolates necessarily engage the sialic acid (SA) moieties
Externí odkaz:
https://doaj.org/article/b10ba61f1ab04f1f9113c099a70c79d7
Autor:
Laty G. Thiam, Prince B. Nyarko, Kwadwo A. Kusi, Makhtar Niang, Yaw Aniweh, Gordon A. Awandare
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Human erythrocytes are indispensable for Plasmodium falciparum development. Unlike other eukaryotic cells, there is no existing erythroid cell line capable of supporting long-term P. falciparum in vitro experiments. Consequently, invasion ph
Externí odkaz:
https://doaj.org/article/cae7a8e92e654596bfc0b1d9283e9146
Autor:
Emmanuel Amlabu, Philip Ilani, Grace Opoku, Prince B. Nyarko, Evelyn Quansah, Laty G. Thiam, Manfred Anim, Reuben Ayivor-Djanie, Ojo-ajogu Akuh, Henrietta Mensah-Brown, Julian C. Rayner, Gordon A. Awandare
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Nearly half of the genes in the Plasmodium falciparum genome have not yet been functionally investigated. We used homology-based structural modeling to identify multiple copies of Armadillo repeats within one uncharacterized gene expressed during the
Externí odkaz:
https://doaj.org/article/37e7c64db27a4e3f91e6e2e225d6a275
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 12
Ex vivo phenotyping of P. falciparum erythrocyte invasion diversity is important in the identification and down selection of potential malaria vaccine targets. However, due to the lack of appropriate laboratory facilities in remote areas of endemic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5a5804fe452622d4b276bdee80f30e
https://doi.org/10.3389/fcimb.2022.997418
https://doi.org/10.3389/fcimb.2022.997418
Autor:
Kwadwo A. Kusi, Jacob K. Donkor, Laty G. Thiam, Yaw Aniweh, Theresa Manful Gwira, Gordon A. Awandare, Makhtar Niang, Evelyn Quansah
Publikováno v:
Experimental Biology and Medicine. 245:11-20
Plasmodium falciparum erythrocyte invasion phenotyping assays are a very useful tool for assessing parasite diversity and virulence, and for characterizing the formation of ligand–receptor interactions. However, such assays need to be highly sensit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4b004a470797dda730e258476517ca
https://doi.org/10.1177/1535370219897393
https://doi.org/10.1177/1535370219897393
Autor:
Nafissatou Diagne, Adja Fatou Mbodj, Laty G. Thiam, Cheikh Talla, Mirco Sandfort, Ivo Mueller, Aissatou Toure-Balde, Inès Vigan-Womas, Cheikh Sokhna, Joseph Faye, Abdoulaye Badiane, Rokhaya Sane, Michael T. White, Babacar Diouf, Thiam A, Makhtar Niang, Fatoumata Diene Sarr
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (12), pp.2175-2183. ⟨10.1093/cid/ciab161⟩
Clinical Infectious Diseases, 2021, 73 (12), pp.2175-2183. ⟨10.1093/cid/ciab161⟩
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (12), pp.2175-2183. ⟨10.1093/cid/ciab161⟩
Clinical Infectious Diseases, 2021, 73 (12), pp.2175-2183. ⟨10.1093/cid/ciab161⟩
Background A detailed understanding of the contribution of the asymptomatic Plasmodium reservoir to the occurrence of clinical malaria at individual and community levels is needed to guide effective elimination interventions. This study investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c646c98d62955c908db948e263ea12
https://hal-pasteur.archives-ouvertes.fr/pasteur-03506546
https://hal-pasteur.archives-ouvertes.fr/pasteur-03506546
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Infectious Diseases
BMC Infectious Diseases
Background About 80% of all reported sickle cell disease (SCD) cases in children anually are recorded in Africa. Although malaria is considered a major cause of death in SCD children, there is limited data on the safety and effectiveness of the avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c581b6d75407d77d65a41d8037f0e8
http://link.springer.com/article/10.1186/s12879-018-3556-0
http://link.springer.com/article/10.1186/s12879-018-3556-0
Autor:
Kwadwo A. Kusi, Collins M. Morang’a, Gordon A. Awandare, Matthew K. Higgins, Evelyn Quansah, Eric Kyei-Baafour, Jessica Asante, Katherine E. Wright, Laty G. Thiam, Yaw Aniweh, Felix Ansah, Prince B. Nyarko, Jonathan Suurbaar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Despite significant progress in controlling malaria, the disease remains a global health burden. The intricate interactions the parasite Plasmodium falciparum has with its host allows it to grow and multiply in human erythrocytes. The mechanism by wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ce042a0334bbf1b6cda9c4f5a368a0
https://pubmed.ncbi.nlm.nih.gov/32001728
https://pubmed.ncbi.nlm.nih.gov/32001728