Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Latoya E. Campbell"'
Autor:
Samantha E. Day, Luis A. Garcia, Richard L. Coletta, Latoya E. Campbell, Tonya R. Benjamin, Elena A. De Filippis, James A. Madura, Lawrence J. Mandarino, Lori R. Roust, Dawn K. Coletta
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-8 (2017)
Abstract Background Obesity is a disease that is caused by genetic and environmental factors. However, epigenetic mechanisms of obesity are less well known. DNA methylation provides a mechanism whereby environmental factors can influence gene transcr
Externí odkaz:
https://doaj.org/article/e5539ef6db004a798f4f906936a191fe
Autor:
Samantha E. Day, Richard L. Coletta, Joon Young Kim, Luis A. Garcia, Latoya E. Campbell, Tonya R. Benjamin, Lori R. Roust, Elena A. De Filippis, Lawrence J. Mandarino, Dawn K. Coletta
Publikováno v:
Epigenetics, Vol 12, Iss 4, Pp 254-263 (2017)
Obesity can increase the risk of complex metabolic diseases, including insulin resistance. Moreover, obesity can be caused by environmental and genetic factors. However, the epigenetic mechanisms of obesity are not well defined. Therefore, the identi
Externí odkaz:
https://doaj.org/article/2c36f13ad8264b419623cd94f2923daa
Autor:
Latoya E. Campbell, Aaron M. Anderson, Yongbin Chen, Scott M. Johnson, Cailin E. McMahon, Jun Liu
Publikováno v:
Journal of Cell Science. 135
G0S2 and HIG2 are two selective inhibitors of ATGL (also known as PNPLA2), the key enzyme for intracellular lipolysis. Whereas G0S2 regulates triglyceride (TG) mobilization in adipocytes and hepatocytes, HIG2 functions to enhance intracellular TG acc
Autor:
Dawn K Coletta, Latoya E Campbell, Jennifer Weil, Bruce Kaplan, Marie Clarkson, Jean Finlayson, Lawrence J Mandarino, Harini A Chakkera
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160327 (2016)
INTRODUCTION:Decreased insulin sensitivity blunts the normal increase in gene expression from skeletal muscle after exercise. In addition, chronic inflammation decreases insulin sensitivity. Chronic kidney disease (CKD) is an inflammatory state. How
Externí odkaz:
https://doaj.org/article/64fd0358aa2b45aa8be6382d146556a0
Publikováno v:
Diabetes
Melanocortin 2 receptor accessory protein (MRAP) is highly expressed in adrenal gland and adipose tissue. In adrenal cells, MRAP is essential for adrenocorticotropic hormone (ACTH)–induced activation of the cAMP/protein kinase A (PKA) pathway by me
Autor:
Elena A. De Filippis, Tonya R. Benjamin, James A. Madura, Lawrence J. Mandarino, Latoya E. Campbell, Luis A. Garcia, Dawn K. Coletta, Richard L. Coletta, Samantha E. Day, Lori R. Roust
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-8 (2017)
Clinical Epigenetics
Clinical Epigenetics
Background Obesity is a disease that is caused by genetic and environmental factors. However, epigenetic mechanisms of obesity are less well known. DNA methylation provides a mechanism whereby environmental factors can influence gene transcription. T
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1862(10 Pt)
The discovery of adipose triglyceride lipase (ATGL) and its coactivator comparative gene identification-58 (CGI-58) provided a major paradigm shift in the understanding of intracellular lipolysis in both adipocytes and nonadipocyte cells. The subsequ
Autor:
Elena A. De Filippis, Samantha E. Day, Joon Young Kim, Tonya R. Benjamin, Richard L. Coletta, Lawrence J. Mandarino, Lori R. Roust, Luis A. Garcia, Latoya E. Campbell, Dawn K. Coletta
Publikováno v:
Epigenetics. 12(4)
Obesity can increase the risk of complex metabolic diseases, including insulin resistance. Moreover, obesity can be caused by environmental and genetic factors. However, the epigenetic mechanisms of obesity are not well defined. Therefore, the identi
Autor:
Bruce Kaplan, Dawn K. Coletta, Harini A. Chakkera, Lawrence J. Mandarino, Jean Finlayson, Jennifer Weil, Marie Clarkson, Latoya E. Campbell
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160327 (2016)
PLoS ONE, Vol 11, Iss 8, p e0160327 (2016)
Introduction Decreased insulin sensitivity blunts the normal increase in gene expression from skeletal muscle after exercise. In addition, chronic inflammation decreases insulin sensitivity. Chronic kidney disease (CKD) is an inflammatory state. How
Autor:
Jill Bargonetti, Gareth L. Bond, Nicoleta C. Arva, Latoya E. Campbell, Kathryn E. Talbott, David E. White, Arnold J. Levine, Agustin Chicas, Tamara Gopen
In cancer cells, the function of the tumor suppressor protein p53 is usually blocked. Impairment of the p53 pathway results in tumor cells with endogenous overexpression of Mdm2 via a naturally occurring single nucleotide polymorphism (SNP) in the md
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dace1624c03f112042869bd5cb64755c
https://ora.ox.ac.uk/objects/uuid:6c56fbf1-6202-4eb6-a891-7c181175d7ed
https://ora.ox.ac.uk/objects/uuid:6c56fbf1-6202-4eb6-a891-7c181175d7ed