Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Latifa H. Youssef"'
Publikováno v:
Scopus-Elsevier
Arom. amides 4 (3-aroyl-2,2,4,4-tetramethyloxazolidines or TMO amides) derived by acylation of 2,2,4,4-tetramethyloxazolidine undergo ortho- and lateral lithiation reactions. Given sufficient steric hindrance to bond rotation, they exhibit atropisome
Publikováno v:
Organic Letters. 3:4133-4136
The double ortholithiation and electrophilic quench of N,N,N'N'-tetraisopropylbiphenyl-2,2'-dicarboxamide 1 is diastereoselective, giving the chiral, C(2)-symmetric atropisomers of the 3,3'-disubstituted products 3. These chiral atropisomers can be c
Publikováno v:
Tetrahedron Letters. 41:5171-5175
Tertiary 9,9-dimethylxanthene-4,5-dicarboxamides have a C 2 -symmetric, axially chiral ground state due to remote interactions between the conformationally constrained tertiary amide substituents. Double ortholithiation–alkylation blocks amide rota
Autor:
Giles Robert Gordon, Lewis Norman John, Latifa H. Youssef, Michael Urquhart, Sasse Michael John, Quick John Kirby
Publikováno v:
Tetrahedron. 56:4531-4537
The novel regiospecific and general reduction of 5-benzylidene-2,4-thiazolidinediones and 5-benzylidene-4-oxo-2-thiazolidinethiones to the corresponding 5-benzyl derivatives has been accomplished using lithium borohydride in pyridine and tetrahydrofu
Publikováno v:
ChemInform. 33
Arom. amides 4 (3-aroyl-2,2,4,4-tetramethyloxazolidines or TMO amides) derived by acylation of 2,2,4,4-tetramethyloxazolidine undergo ortho- and lateral lithiation reactions. Given sufficient steric hindrance to bond rotation, they exhibit atropisome
Publikováno v:
ChemInform. 33
Ortholithiation and reaction with (−)-menthyl p-toluenesulfinate introduces a sulfoxide substituent ortho to the stereogenic Ar−CO axis of an aromatic amide. The sulfoxide exerts a powerful conformational bias on the axis, such that after rapid e
Autor:
Neoclis Vassiliou, Neil Westlund, Mark S. Betson, Samreen A. Yasin, Paul V. Johnson, Christopher C. Stimson, Jennifer H. Pink, Lai Wah Lai, Madeleine Helliwell, Latifa H. Youssef, Jonathan Clayden
Publikováno v:
Organic and biomolecular chemistry. 4(3)
Tertiary aromatic amides bearing stereogenic centres ortho to the amide group may adopt two diastereoisomeric conformations which interconvert slowly on the NMR timescale at ambient temperature, and are therefore detectable by NMR. Certain classes of
Autor:
Latifa H. Youssef, Lewis Norman John, Giles Robert Gordon, Quick John Kirby, Michael Urquhart, Sasse Michael John
Publikováno v:
ChemInform. 31
The novel regiospecific and general reduction of 5-benzylidene-2,4-thiazolidinediones and 5-benzylidene-4-oxo-2-thiazolidinethiones to the corresponding 5-benzyl derivatives has been accomplished using lithium borohydride in pyridine and tetrahydrofu
Publikováno v:
Journal of the American Chemical Society. 124:5266-5267
Ortholithiation and reaction with (-)-menthyl p-toluenesulfinate introduces a sulfoxide substituent ortho to the stereogenic Ar-CO axis of an aromatic amide. The sulfoxide exerts a powerful conformational bias on the axis, such that after rapid equil