Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Latha B. Pathangey"'
Autor:
Latha B. Pathangey, Vani Lakshminarayanan, Vera J. Suman, Barbara A. Pockaj, Pinku Mukherjee, Sandra J. Gendler
Publikováno v:
Biomolecules, Vol 6, Iss 3, p 31 (2016)
Cancer vaccines have often failed to live up to their promise, although recent results with checkpoint inhibitors are reviving hopes that they will soon fulfill their promise. Although mutation-specific vaccines are under development, there is still
Externí odkaz:
https://doaj.org/article/f03caf596dbf42ac9686832a116a0c2c
Autor:
Sandra J. Gendler, Latha B. Pathangey, P. Leif Bergsagel, Trupti Vardam-Kaur, Daniel J. McCormick, Peter A. Cohen
Publikováno v:
Oncotarget. 12:2051-2067
Multiple Myeloma (MM) patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses. Here we evaluate the possibility of adoptive cell tr
Autor:
Trupti, Vardam-Kaur, Latha B, Pathangey, Daniel J, McCormick, P Leif, Bergsagel, Peter A, Cohen, Sandra J, Gendler
Publikováno v:
Oncotarget
Multiple Myeloma (MM) patients suffer disease relapse due to the development of therapeutic resistance. Increasing evidence suggests that immunotherapeutic strategies can provide durable responses. Here we evaluate the possibility of adoptive cell tr
Autor:
Vera J. Suman, Latha B. Pathangey, Vani Lakshminarayanan, Barbara A. Pockaj, Sandra J. Gendler, Pinku Mukherjee
Publikováno v:
Biomolecules; Volume 6; Issue 3; Pages: 31
Biomolecules
Biomolecules, Vol 6, Iss 3, p 31 (2016)
Biomolecules
Biomolecules, Vol 6, Iss 3, p 31 (2016)
Cancer vaccines have often failed to live up to their promise, although recent results with checkpoint inhibitors are reviving hopes that they will soon fulfill their promise. Although mutation-specific vaccines are under development, there is still
Autor:
Amanda Maree Walmsley, M. Lucrecia Alvarez, Sandra J. Gendler, Hugh S. Mason, Julia Pinkhasov, Pinku Mukherjee, Teresa L. Tinder, Latha B. Pathangey
Publikováno v:
Cancer Immunology, Immunotherapy. 59:1801-1811
Since epithelial mucin 1 (MUC1) is associated with several adenocarcinomas at the mucosal sites, it is pertinent to test the efficacy of a mucosally targeted vaccine formulation. The B subunit of the Vibrio cholerae cholera toxin (CTB) has great pote
Autor:
J.B. Bradley, Emmanuel T. Akporiaye, Pinku Mukherjee, Latha B. Pathangey, Gargi D. Basu, Sandra J. Gendler, Teresa L. Tinder
Publikováno v:
Vaccine. 25:1607-1618
A MUC1-based vaccine was used in a preclinical model of colon cancer. The trial was conducted in a MUC1-tolerant immune competent host injected with MC38 colon cancer cells expressing MUC1. The vaccine included: MHC class I-restricted MUC1 peptides,
Autor:
Gargi D. Basu, Latha B. Pathangey, Teresa L. Tinder, Michelle LaGioia, Sandra J. Gendler, Pinku Mukherjee
Publikováno v:
Molecular Cancer Research. 2:632-642
Cyclooxygenase-2 (COX-2) inhibitors are rapidly emerging as a new generation of therapeutic drug in combination with chemotherapy or radiation therapy for the treatment of cancer. The mechanisms underlying its antitumor effects are not fully understo
Autor:
Jose L. Hernandez, Barbara A. Pockaj, Richard Gray, Gargi D. Basu, Latha B. Pathangey, Sandra J. Gendler, Pinku Mukherjee
Publikováno v:
Annals of Surgical Oncology. 11:328-339
In several neoplastic diseases, including breast cancer, immunosuppression correlates with disease stage, progression, and outcome. Thus, thorough analysis of immune parameters in breast cancer patients may be beneficial in designing effective antica
Autor:
James H. Finke, Patricia Rayman, Judy M. Bradley, Jessica E. Gorman, Walter J. Storkus, Soroya Zorro-Manrique, Peter A. Cohen, Anna Lucia Dominguez, Brian I. Rini, Sandra J. Gendler, Dustin B. McCurry, Latha B. Pathangey, Christopher D. Spencer, Jennifer S. Ko
Publikováno v:
Immunological investigations. 41(6-7)
The receptor tyrosine kinase inhibitor, sunitinib, is astonishingly effective in its capacity to reduce MDSCs in peripheral tissues such as blood (human) and spleen (mouse), restoring responsiveness of bystander T lymphocytes to TcR stimulation. Suni
Autor:
Geert-Jan Boons, Cathy S. Madsen, Sandra J. Gendler, Judy M. Bradley, Vani Lakshminarayanan, Latha B. Pathangey, Margreet A. Wolfert, Pamela Thompson, Therese Buskas, Peter A. Cohen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(1)
The mucin MUC1 is typically aberrantly glycosylated by epithelial cancer cells manifested by truncated O -linked saccharides. The resultant glycopeptide epitopes can bind cell surface major histocompatibility complex (MHC) molecules and are susceptib