Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Lata Adnani"'
Autor:
Cristiana Spinelli, Lata Adnani, Brian Meehan, Laura Montermini, Sidong Huang, Minjun Kim, Tamiko Nishimura, Sidney E. Croul, Ichiro Nakano, Yasser Riazalhosseini, Janusz Rak
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Targeting neovascularization in glioblastoma (GBM) is hampered by poor understanding of the underlying mechanisms and unclear linkages to tumour molecular landscapes. Here we report that different molecular subtypes of human glioma stem cell
Externí odkaz:
https://doaj.org/article/5f16d7dd93a34bec93a7e29368874678
Publikováno v:
Bleeding, Thrombosis and Vascular Biology, Vol 3, Iss s1 (2024)
Cancer-associated thrombosis (CAT) results from the hemostatic system being dysregulated by the progression of cancer. Despite common clinical manifestations, the mechanisms of CAT may vary greatly because cancers develop along distinct biological tr
Externí odkaz:
https://doaj.org/article/09d4b30e1ddb4fd29d52ded2b8eb2424
Autor:
Lata Adnani, Jordan Kassouf, Brian Meehan, Cristiana Spinelli, Nadim Tawil, Ichiro Nakano, Janusz Rak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Glioma stem-like cells (GSCs) exhibit plasticity during proneural-to-mesenchymal transition. Here the authors show that extracellular vesicles from endothelial cells can promote this transition of GSCs through activation of MMPs and NFkB, and inactiv
Externí odkaz:
https://doaj.org/article/9fc37250e87a4721843dcf75d51a9476
Autor:
Shiekh Tanveer Ahmad, Alexandra D. Rogers, Myra J. Chen, Rajiv Dixit, Lata Adnani, Luke S. Frankiw, Samuel O. Lawn, Michael D. Blough, Mana Alshehri, Wei Wu, Marco A. Marra, Stephen M. Robbins, J. Gregory Cairncross, Carol Schuurmans, Jennifer A. Chan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Although Capicua (Cic), a transcriptional repressor, is linked to cancer, little is known about its function in the non-diseased brain. Here, authors show that Cic is strongly expressed in astrocytic and neuronal lineage cells during development and
Externí odkaz:
https://doaj.org/article/7c701ae587344f44b0639d92de89cde9
Autor:
Lata Adnani, Rajiv Dixit, Xingyu Chen, Anjali Balakrishnan, Harshil Modi, Yacine Touahri, Cairine Logan, Carol Schuurmans
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
The Plag gene family has three members; Plagl1/Zac1, which is a tumor suppressor gene, and Plag1 and Plagl2, which are proto-oncogenes. All three genes are known to be expressed in embryonic neural progenitors, and Zac1 regulates proliferation, neuro
Externí odkaz:
https://doaj.org/article/0ed1111a88fc433493063216a053ea02
Autor:
Nobuhiko Tachibana, Yacine Touahri, Rajiv Dixit, Luke Ajay David, Lata Adnani, Robert Cantrup, Tooka Aavani, Rachel O. Wong, Cairine Logan, Kyle C. Kurek, Carol Schuurmans
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 5 (2018)
PTEN hamartoma tumour syndrome (PHTS) is a heterogeneous group of rare, autosomal dominant disorders associated with PTEN germline mutations. PHTS patients routinely develop hamartomas, which are benign tissue overgrowths comprised of disorganized
Externí odkaz:
https://doaj.org/article/5e67aa0a2baf45eab61369be85e5394f
Publikováno v:
Non-Coding RNA, Vol 5, Iss 1, p 1 (2018)
Non-coding RNA (ncRNA) species have emerged in as molecular fingerprints and regulators of brain tumor pathogenesis and progression. While changes in ncRNA levels have been traditionally regarded as cell intrinsic there is mounting evidence for their
Externí odkaz:
https://doaj.org/article/194d93d47a8f4ce3b215ff38b8cae1c4
Publikováno v:
Seminars in Cancer Biology. 87:196-213
Cancer progression impacts and exploits the vascular system in several highly consequential ways. Among different types of vascular cells, blood cells and mediators that are engaged in these processes, endothelial cells are at the centre of the under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1ce9aa231cedf8decd907ecb088e97
https://doi.org/10.1016/j.semcancer.2022.11.003
https://doi.org/10.1016/j.semcancer.2022.11.003
Autor:
Yacine Touahri, Luke Ajay David, Joseph Hanna, Satoshi Okawa, Hedy Liu, Yucheng Xiao, Alissa Pak, Yaroslav Ilnytskyy, Edwin van Oosten, Nobuhiko tachibana, Lata Adnani, Jiayi Zhao, Mary Hoffman, Rajiv Dixit, Dawn Zinyk, Cynthia J. Guidos, Volker Enzmann, Pengpeng Bi, Isabelle Aubert, Laurent Journot, Igor Kovalchuk, Yves Sauvé, Jeff Biernaskie, Chao Wang, Antonio del Sol, Carol Janine Schuurmans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d25af604eeefe9fc3b34d7ffa7aa67
https://doi.org/10.2139/ssrn.4423987
https://doi.org/10.2139/ssrn.4423987
Autor:
Caterina Facchin, Ana Belen Fraga Timiraos, Brian Meehan, Nadia Babaa, Lata Adnani, Anne-Laure Larroque, Janusz Rak, Bertrand J Jean-Claude
Publikováno v:
Cancer Research. 83:1647-1647
Introduction. Glioblastoma multiforme (GBM) is the most aggressive form of primary brain tumours with an average survival rate of 12-18 months. The existing treatment (chemotherapy with temozolomide (TMZ)+radiotherapy) increases the median survival b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c5fe22013c7ef276c5f21ee18fea24
https://doi.org/10.1158/1538-7445.am2023-1647
https://doi.org/10.1158/1538-7445.am2023-1647