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Lipid Peroxidation and Type I Interferon Coupling Fuels Pathogenic Macrophage Activation Causing Tuberculosis Susceptibility.

Autor: Yabaji SM; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin 4, Ireland., Araveti PB; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA., Lata S; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA., Rukhlenko OS; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin 4, Ireland., Al Abdullatif S; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA., Vanvalkenburg A; Rutgers University, New Jersey Medical School, Division of Infectious Disease, Department of Medicine.; Rutgers University, New Jersey Medical School, Center for Data Science., Alekseev Y; The Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118., Ma Q; Department of Biochemistry, and Cell Biology and Genome Science Institute, Boston University Chobanian & Avedisian School of Medicine., Dayama G; Department of Biochemistry, and Cell Biology and Genome Science Institute, Boston University Chobanian & Avedisian School of Medicine., Lau NC; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA.; Department of Biochemistry, and Cell Biology and Genome Science Institute, Boston University Chobanian & Avedisian School of Medicine., Johnson WE; Rutgers University, New Jersey Medical School, Division of Infectious Disease, Department of Medicine.; Rutgers University, New Jersey Medical School, Center for Data Science., Bishai WR; Center for TB Research, Johns Hopkins School of Medicine, Baltimore, Maryland., Crossland NA; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA.; The Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118., Campbell JD; Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA., Kholodenko BN; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin 4, Ireland.; Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin 4, Ireland.; Department of Pharmacology, Yale University School of Medicine, New Haven CT, USA., Gimelbrant AA; Altius Institute for Biomedical Sciences, Seattle, WA, USA., Kobzik L; Cellecta, Inc., Mountain View, CA., Kramnik I; The National Emerging Infectious Diseases Laboratory, Boston University, Boston, MA.; Pulmonary Center, The Department of Medicine, Boston University Chobanian & Avedisian School of Medicine.; Dept. of Microbiology, Boston University Chobanian & Avedisian School of Medicine.; Lead Contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 25. Date of Electronic Publication: 2024 Sep 25.