Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Laszlo Wenchich"'
Autor:
Zuzana Jackova, Jan J. Stepan, Stepan Coufal, Martin Kostovcik, Natalie Galanova, Zuzana Reiss, Karel Pavelka, Laszlo Wenchich, Hana Hruskova, Miloslav Kverka
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimsOvarian hormone deficiency is one of the main risk factors for osteoporosis and bone fractures in women, and these risks can be mitigated by menopausal hormone therapy. Recent evidence suggests that gut microbiota may link changes in estrogen lev
Externí odkaz:
https://doaj.org/article/87b036fb08f74ff3ad05c7428b452402
Autor:
Jiri Baloun, Aneta Pekacova, Laszlo Wenchich, Hana Hruskova, Ladislav Senolt, Xiao Svec, Karel Pavelka, Jan J. Stepan
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveOsteoporosis is associated with an impaired balance between bone resorption and formation, which in turn leads to bone loss and fractures. Many recent studies have underlined the regulatory role of microRNAs (miRNAs) in bone remodeling proce
Externí odkaz:
https://doaj.org/article/ebcc11f44d3d4638bb464ed17dafca3c
Autor:
Hana Hansikova, Eva Kitzlerová, Jiří Zeman, Jana Hroudová, Roman Jirák, Jiří Raboch, Zdeněk Fišar, Martina Zvěřová, Laszlo Wenchich, Jana Křížová
Publikováno v:
Mitochondrion. 48:67-77
We analyzed activities of complex I, II, III, and IV, and citrate synthase (CS) in patients with major depressive disorder (MDD) or Alzheimer's disease (AD) presenting with or without depression. Associations of these parameters with disease or disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32507f0a2d7e81b42db45c23cb8d20f3
https://doi.org/10.1016/j.mito.2019.07.013
https://doi.org/10.1016/j.mito.2019.07.013
Autor:
Vaclav Hana, Martin Haluzik, Hana Hansikova, Michal Krsek, Jana Ježková, V. Ďurovcová, Josef Marek, Zdeňka Lacinová, Jiří Zeman, Laszlo Wenchich
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 12:1459-1471
Purpose Cushing's syndrome is characterized by metabolic disturbances including insulin resistance. Mitochondrial dysfunction is one pathogenic factor in the development of insulin resistance in patients with obesity. We explored whether mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dacffbdcb12b3496b683859a0467a96e
https://doi.org/10.2147/dmso.s209095
https://doi.org/10.2147/dmso.s209095
Autor:
Jana Klouckova, P Trachta, M. Urbanova, Michal Krsek, Denisa Haluzikova, Laszlo Wenchich, Martin Haluzik, Hana Hansikova, V. Ďurovcová, P Kaválková, Milos Mraz, Zdeňka Lacinová
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Mitochondrial dysfunction is a potentially important player in the development of insulin resistance and type 2 diabetes mellitus (T2DM). We investigated the changes of mRNA expression of genes encoding main enzymatic complexes of mitochondrial respi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6062fd21739d80dc57c474bb0988b745
https://pubmed.ncbi.nlm.nih.gov/28730835
https://pubmed.ncbi.nlm.nih.gov/28730835
Autor:
Jiri Zeman, Daniela Fornuskova, Kamila Vinsova, Lukas Stiburek, Laszlo Wenchich, Olga Kostkova, Josef Houstek, Jana Cesnekova
Publikováno v:
Molecular Biology of the Cell
Loss-of-function studies show that the human mitochondrial YME1L protease ensures cell proliferation, maintains normal cristae morphology and complex I activity, acts in an antiapoptotic manner, protects mitochondria from accumulation of oxidatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fd59161f0245227f0a9e480c0e8c0f
https://doi.org/10.1091/mbc.e11-08-0674
https://doi.org/10.1091/mbc.e11-08-0674
Autor:
Marketa Tesarova, Jiri Zeman, Johannes A. Mayr, Karol Szentivanyi, Wolfgang Sperl, Katerina Vesela, Tomas Honzik, Hana Hansikova, Martin Magner, Laszlo Wenchich, Pavel Ješina
Publikováno v:
Journal of Inherited Metabolic Disease. 35:749-759
Mitochondrial disorders (MD) may manifest in neonates, but early diagnosis is difficult. In this study, clinical and laboratory data were analyzed in 129 patients with neonatal onset of MD to identify any association between specific mitochondrial di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1066d9217e97ec461ef39a52f5171d40
https://doi.org/10.1007/s10545-011-9440-3
https://doi.org/10.1007/s10545-011-9440-3
Autor:
Hana Hansikova, Tomas Honzik, Lukas Stiburek, Marketa Tesarova, Laszlo Wenchich, Evzenie Tietzeova, Olga Brantova, Daniela Fornuskova, Jiri Zeman
Publikováno v:
Biochimica et Biophysica Acta-Molecular Basis of Disease
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2008, 1782 (5), pp.317. ⟨10.1016/j.bbadis.2008.02.001⟩
Biochimica et Biophysica Acta-Molecular Basis of Disease, Elsevier, 2008, 1782 (5), pp.317. ⟨10.1016/j.bbadis.2008.02.001⟩
The impact of point mutations in mitochondrial tRNA genes on the amount and stability of respiratory chain complexes and ATP synthase (OXPHOS) has been broadly characterized in cultured skin fibroblasts, skeletal muscle samples, and mitochondrial cyb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec4c604c6a1bb653f920be1b23217b5
https://doi.org/10.1016/j.bbadis.2008.02.001
https://doi.org/10.1016/j.bbadis.2008.02.001
Publikováno v:
International Journal of Eating Disorders. 40:659-663
Objective: A broad spectrum of endocrine and biochemical disturbances was observed in patients with anorexia nervosa. In addition, metabolic changes may concern the efficiency of mitochondrial energy generating system. In our study we analyzed the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313b94cf6c4f9a14a4fb9b900b114149
https://doi.org/10.1002/eat.20403
https://doi.org/10.1002/eat.20403
Publikováno v:
Neonatology. 81:229-235
The activity, amount and protein composition of pyruvate dehydrogenase (PDH) and respiratory chain complexes were studied in muscle mitochondria obtained postmortally from 6 neonates with a gestational age of 23–29 weeks. The activities of PDH and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136de827f2b9cf8ce34bab707772fc34
https://doi.org/10.1159/000056753
https://doi.org/10.1159/000056753