Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Laszlo Orfi"'
Autor:
Gyula Bencze, Szilvia Bencze, Keith D. Rivera, James D. Watson, Mate Hidvegi, Laszlo Orfi, Nicholas K. Tonks, Darryl J. Pappin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/c47f7a261d114bd4873160c6a67d63d1
Autor:
Attila Szabo, Judit Hodrea, Andrea Fekete, Laszlo Orfi, Anna Balogh, Beáta Szebeni, Agnes Molnar, Tamas Lakat, Adam Hosszu
Publikováno v:
Amino Acids
Lyophilization is a cost-effective method for biological specimen preservation but detailed tissue-specific reference protocols are still lacking. Moreover, data are limited on the long-term stability of proteins and nucleic acids in lyophilized samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8efb0ffe47b06ac306ba85e0f4f66fe
http://europepmc.org/articles/PMC8128086
http://europepmc.org/articles/PMC8128086
Autor:
Keith Rivera, Nicholas K. Tonks, Szilvia Bencze, Darryl J. Pappin, Gyula Bencze, Mate Hidvegi, James D. Watson, Laszlo Orfi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Mitochondrial dysfunction and significant changes in metabolic pathways accompany cancer development and are responsible for maintaining the tumor microenvironment. Normal mitochondria can trigger intrinsic apoptosis by releasing cytochrome c into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd1b621312aeef8af3d0115792d2a57
http://europepmc.org/articles/PMC7846729
http://europepmc.org/articles/PMC7846729
Autor:
James D. Watson, Mate Hidvegi, Gyula Bencze, Keith Rivera, Nicholas K. Tonks, Szilvia Bencze, Darryl J. Pappin, Laszlo Orfi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Mitochondrial dysfunction and significant changes in metabolic pathways accompany cancer development and are responsible for maintaining the tumor microenvironment. Normal mitochondria can trigger intrinsic apoptosis by releasing cytochrome c into th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df97508de0d20470517ed6e629a61118
https://doi.org/10.1038/s41598-020-71118-3
https://doi.org/10.1038/s41598-020-71118-3
Autor:
Felix Dietlein, Roman K. Thomas, Martin Peifer, Daniel Rauh, Zoltán Varga, Johannes M. Heuckmann, Axel Choidas, Johannes Brägelmann, Jan Eickhoff, Carina Lorenz, Hyatt Balke-Want, György Kéri, Zhizhou Fang, Stefanie Böhm, Zoltán Greff, Muhammad Sallouh, Martin Termathe, Reinhard Büttner, Debjit Basu, Christopher A. French, Uwe Koch, Frauke Leenders, André Richters, Martin L. Sos, Verena Tischler, Bert Klebl, Sascha Ansén, Peter Habenberger, Laszlo Orfi, Matthäus Getlik, Sandra Ortiz-Cuaran, Marcel A. Dammert, Lukas C. Heukamp, H. Christian Reinhardt
Publikováno v:
Cell Reports
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Cell Reports, Vol 20, Iss 12, Pp 2833-2845 (2017)
Summary Kinase inhibitors represent the backbone of targeted cancer therapy, yet only a limited number of oncogenic drivers are directly druggable. By interrogating the activity of 1,505 kinase inhibitors, we found that BRD4-NUT-rearranged NUT midlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfadea6b1ad3b4323f2fa27e4edbd58
http://europepmc.org/articles/PMC5622049
http://europepmc.org/articles/PMC5622049
Autor:
Franz Bracher, Martin Neuenschwander, Wendy S. Barclay, Laszlo Orfi, Thomas F. Meyer, István Szabadkai, Zoltán Horváth, Nikolaus Hilz, Yael Domovich-Eisenberg, Rebecca Frise, Kilian Huber, Michael Meyer, Yu Jin Shin, Tsafi Danieli, Noa Dekel, Sigrid Goedert, Anita Artarini, György Kéri, Jens Peter von Kries, Oded Livnah, Alexander Karlas, Dániel Eros, Olivier Moncorgé, Mario Lebendiker
Publikováno v:
Antiviral Research
Influenza A virus carries eight negative single-stranded RNAs and uses spliced mRNAs to increase the number of proteins produced from them. Several genome-wide screens for essential host factors for influenza A virus replication revealed a necessity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e204488c6bd42d4000b10421ab4a0257
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Adviye Ergul, Maribeth H. Johnson, Susan C. Fagan, Laszlo Orfi, Azza B. El-Remessy, Maha Coucha, Weiguo Li, Mohammed Abdelsaid
Publikováno v:
Life Sciences. 163:46-54
Ischemia/reperfusion and the resulting oxidative/nitrative stress impair cerebral myogenic tone via actin depolymerization. While it is known that NADPH oxidase (Nox) family is a major source of vascular oxidative stress; the extent and mechanisms by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125f7815e81909dc6e239468828450da
https://doi.org/10.1016/j.lfs.2016.08.018
https://doi.org/10.1016/j.lfs.2016.08.018
Autor:
Zoltan Örfi, Laszlo Orfi, István Szabadkai, Ferenc Baska, Axel Ullrich, Robert Torka, Jana Hartmann, F. Waczek
Publikováno v:
Scientific Reports
According to clinical data, some tyrosine kinase inhibitors (TKIs) possess antidiabetic effects. Several proposed mechanisms were assigned to them, however their mode of action is not clear. Our hypothesis was that they directly stimulate insulin rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5769a15e2b86c39021a1bc46cfda053c
https://hdl.handle.net/11858/00-001M-0000-002D-E673-A11858/00-001M-0000-002D-E674-811858/00-001M-0000-002D-E675-611858/00-001M-0000-002D-E676-411858/00-001M-0000-002D-E671-E
https://hdl.handle.net/11858/00-001M-0000-002D-E673-A11858/00-001M-0000-002D-E674-811858/00-001M-0000-002D-E675-611858/00-001M-0000-002D-E676-411858/00-001M-0000-002D-E671-E
Autor:
Laszlo Orfi, Christine Baumann, Gyoergy Keri, Axel Ullrich, Robert Torka, István Szabadkai, Kinga Pénzes
Publikováno v:
Cancer Biology & Therapy. 15:1571-1582
Blocking the migration of metastatic cancer cells is a major goal in the therapy of cancer. The receptor tyrosine kinase AXL is one of the main triggers for cancer cell migration in neoplasia of breast, colon, skin, thyroid and prostate. In our study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da854eb006a4762843885c51e17ca668
https://doi.org/10.4161/15384047.2014.956634
https://doi.org/10.4161/15384047.2014.956634
Autor:
Feng Chen, Athanassios Giannis, Reto Asmis, Stephen M. Black, Scott A. Barman, Yunchao Su, Ruslan Rafikov, John D. Catravas, David J Fulton, Nektarios Barabutis, Ganesan Ramesh, Weihong Han, Csaba Szántai-Kis, Danny Jonigk, Christiana Dimitropoulou, Laszlo Orfi, István Szabadkai, David W. Stepp, Yusi Wang, György Kéri, Olga Rafikova
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:1704-1715
Objective— Pulmonary hypertension (PH) is a progressive disease arising from remodeling and narrowing of pulmonary arteries (PAs) resulting in high pulmonary blood pressure and ultimately right ventricular failure. Elevated production of reactive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789e571e85c7b2ad45d8f67020de167c
https://doi.org/10.1161/atvbaha.114.303848
https://doi.org/10.1161/atvbaha.114.303848