Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Laszlo G Boros"'
Autor:
Yonchu Jenkins, Tian-Qiang Sun, Vadim Markovtsov, Marc Foretz, Wei Li, Henry Nguyen, Yingwu Li, Alison Pan, Gerald Uy, Lisa Gross, Kristen Baltgalvis, Stephanie L Yung, Tarikere Gururaja, Taisei Kinoshita, Alexander Owyang, Ira J Smith, Kelly McCaughey, Kathy White, Guillermo Godinez, Raniel Alcantara, Carmen Choy, Hong Ren, Rachel Basile, David J Sweeny, Xiang Xu, Sarkiz D Issakani, David C Carroll, Dane A Goff, Simon J Shaw, Rajinder Singh, Laszlo G Boros, Marc-André Laplante, Bruno Marcotte, Rita Kohen, Benoit Viollet, André Marette, Donald G Payan, Todd M Kinsella, Yasumichi Hitoshi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81870 (2013)
Modulation of mitochondrial function through inhibiting respiratory complex I activates a key sensor of cellular energy status, the 5'-AMP-activated protein kinase (AMPK). Activation of AMPK results in the mobilization of nutrient uptake and cataboli
Externí odkaz:
https://doaj.org/article/9f3bbe0f39b0498d932c53dbf27c0985
Autor:
Youfeng Yang, Andrew N Lane, Christopher J Ricketts, Carole Sourbier, Ming-Hui Wei, Brian Shuch, Lisa Pike, Min Wu, Tracey A Rouault, Laszlo G Boros, Teresa W-M Fan, W Marston Linehan
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72179 (2013)
Fumarate hydratase (FH)-deficient kidney cancer undergoes metabolic remodeling, with changes in mitochondrial respiration, glucose, and glutamine metabolism. These changes represent multiple biochemical adaptations in glucose and fatty acid metabolis
Externí odkaz:
https://doaj.org/article/bcb80a4501e24a8ea16871e56472b9c3
Autor:
Monika A. Golinska, Marion Stubbs, Adrian L. Harris, Laszlo G. Boros, Madhu Basetti, Dominick J. O. McIntyre, John R. Griffiths
Publikováno v:
Cells, Vol 11, Iss 22, p 3595 (2022)
The HIF-1 and HIF-2 (HIF1/2) hypoxia responses are frequently upregulated in cancers, and HIF1/2 inhibitors are being developed as anticancer drugs. How could cancers resist anti-HIF1/2 therapy? We studied metabolic and molecular adaptations of HIF-1
Externí odkaz:
https://doaj.org/article/ad00fee0952b4adab47fb7890628b765
Autor:
Ingrid Melinda Gyalai, Zoltán Répás, Tjaart P. J. Krüger, James C. Lech, Laszlo G. Boros, Sophia I. Dorfsman
Publikováno v:
Metabolomics
Introduction This review addresses metabolic diversities after grain feeding of cattle using artificial total mixed ration (TMR), in place of pasture-based feeding. Objectives To determine how grain feeding impairs the deuterium-depleting functions o
Autor:
Gábor Somlyai, Dominic P. D’Agostino, Laszlo G. Boros, T. Que Collins, Patel Hitendra, Emmanuelle J. Meuillet
Publikováno v:
Oncotarget
// Gabor Somlyai 1 , T. Que Collins 2,3 , Emmanuelle J. Meuillet 4 , Patel Hitendra 5 , Dominic P. D’Agostino 6 and Laszlo G. Boros 7,8,9,10 1 HYD, LLC for Cancer Research & Drug Development, Budapest, Hungary, European Union 2 CignatureHealth Meta
Autor:
Laszlo G. Boros
Publikováno v:
Educatio. 26:3-14
Absztrakt: A politikai szocializacios kutatasok egyertelmű eredmenye volt, hogy a nyolcvanas evek elejere a rendszer latens torekvese, a politikai aktivitastol eltavolitas atfogo sikerrel jart. Az ...
Publikováno v:
Perspectives in biology and medicine. 61(4)
The precision medicine narrative relies on the reductionist assumption that there is a strong linkage between genotype and complex traits (phenotypes). This essay uses examples from humans and other "higher" animals to argue that redundant and degene
Autor:
Dominic P. D’Agostino, Laszlo G. Boros, Howard E. Katz, Emmanuelle J. Meuillet, Justine P. Roth, Gábor Somlyai
Publikováno v:
Medical Hypotheses. 87:69-74
The naturally occurring isotope of hydrogen ((1)H), deuterium ((2)H), could have an important biological role. Deuterium depleted water delays tumor progression in mice, dogs, cats and humans. Hydratase enzymes of the tricarboxylic acid (TCA) cycle c
Autor:
Anju Singh, Vassiliki A. Papadimitrakopoulou, Julian Carretero, Edward Gabrielson, George K. Acquaah-Mensah, Ignacio I. Wistuba, John V. Heymach, Kuladeep Sudini, Shyam Biswal, Ferdinandos Skoulidis, Laszlo G. Boros, Qing Kay Li, Christian Ruiz, Geoffrey D. Girnun, John D. Haley, John A. Haley, Kwok-Kin Wong, Kavita Bhalla, Emily D. Montal
Oncogenic Kras mutations are one of the most common alterations in non-small cell lung cancer and are associated with poor response to treatment and reduced survival. Driver oncogenes, such as Kras are now appreciated for their ability to promote tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4e7261b1f184cdb92d0fa112587d9b
https://europepmc.org/articles/PMC6219836/
https://europepmc.org/articles/PMC6219836/
Autor:
Laszlo G. Boros, Ching-Wei Chang, Vijayalakshmi Varma, Greg T. Nolen, Richard D. Beger, Jim Kaput, Martin Wabitsch
Publikováno v:
Metabolites, Vol 5, Iss 2, Pp 364-385 (2015)
Metabolites
Volume 5
Issue 2
Pages 364-385
Metabolites
Volume 5
Issue 2
Pages 364-385
Increased consumption of sugar and fructose as sweeteners has resulted in the utilization of fructose as an alternative metabolic fuel that may compete with glucose and alter its metabolism. To explore this, human Simpson-Golabi-Behmel Syndrome (SGBS