Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Lasubine II"'
Autor:
Sunil V. Pansare, Seerat Virk
Publikováno v:
Organic letters. 21(14)
An enantioselective, biomimetic organocatalytic synthesis of 4-arylquinolizidin-2-ones, key intermediates in the synthesis of several Lythraceae alkaloids, was developed. The methodology features S...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbda9b6a34afff143214b2ff673e5c6
https://pubmed.ncbi.nlm.nih.gov/31246480
https://pubmed.ncbi.nlm.nih.gov/31246480
Publikováno v:
The Journal of Organic Chemistry. 81:11363-11371
Addition of silyl enol ethers obtained from substituted methyl enones to chiral sulfinimines afforded the β-amino-substituted enones with excellent selectivity. Utility of the obtained N-sulfinyl β-amino ketones possessing α,β-unsaturation is exe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037ee9e293039e129e3dfb179a7c9d5b
https://doi.org/10.1021/acs.joc.6b01541
https://doi.org/10.1021/acs.joc.6b01541
Publikováno v:
Chemistry - An Asian Journal. 11:470-473
The synthesis of (±)-lasubine II has been achieved through a three-component allylation capitalizing on the unique properties of N-methoxyamines. This reaction enabled the installation of all the carbon atoms of lasubine II in a single operation. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1068558b69fddefc517a65fcde0f9f
https://doi.org/10.1002/asia.201501143
https://doi.org/10.1002/asia.201501143
Publikováno v:
Organic Letters. 17:5312-5315
The first examples of an organocatalytic Michael addition of a ketone to in situ generated α-nitrostyrenes are reported. A suitably functionalized γ-nitroketone obtained from the organocatalyzed Michael addition was converted into (+)-2-epi-lasubin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbafecb2faab46590327230eeb130ce7
https://doi.org/10.1021/acs.orglett.5b02677
https://doi.org/10.1021/acs.orglett.5b02677
Akademický článek
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Formal syntheses of lasubine II and subcosine II have been completed by the synthesis of epi-lasubine II. The synthesis involves diastereoselective allylation of a methoxy isoxazolidine and a tandem hydrogenation process leading stereoselectively to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de7adacaf9f67d5a3802d0f9cdedb67
https://hdl.handle.net/10356/83262
https://hdl.handle.net/10356/83262
Publikováno v:
Organic letters. 18(24)
A series of high-yielding silver(I)-catalyzed cyclization reactions of pyridine-, isoquinoline-, and pyrazine-ynones are described. The operationally simple and mild reaction conditions are a significant improvement over previously reported thermal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dd4dafeb3b9df97f70b9ab940e4dd0
https://pubmed.ncbi.nlm.nih.gov/27978692
https://pubmed.ncbi.nlm.nih.gov/27978692
Publikováno v:
Organic Letters. 13:5128-5131
Intramolecular cycloaddition of the syn- and the anti-nitrone 9 and 13 leads stereoselectively to the azabicyclic compounds 10 and 14 which may provide access to both enantiomers of the quinolizidine alkaloid lasubine II.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653a8b913debe29e5d4ec80fa38395ec
https://doi.org/10.1021/ol2019967
https://doi.org/10.1021/ol2019967
Publikováno v:
Synlett. 2009:237-240
The first success in constructing a member of quinolizidine family of alkaloids employing an intramolecular aza-[3 + 3] annulation strategy is described here. The key feature is the usage of vinylogous urethane tethered to a vinyl iminium intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4bbf74102d115b2ade899c5dce1b37
https://doi.org/10.1055/s-0028-1087661
https://doi.org/10.1055/s-0028-1087661
Publikováno v:
The Journal of Organic Chemistry. 72:10294-10297
A concise and efficient approach to the stereodivergent synthesis of (+)-lasubines I and II is described. The key common intermediate is a chiral N-sulfonyl 2,3-dihydropyridone obtained by a novel Cu-catalyzed asymmetric formal aza-Diels-Alder reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406d21e8bd8fc55d43bde590c7592667
https://doi.org/10.1021/jo702076j
https://doi.org/10.1021/jo702076j