SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with Rothia sp

Autor: Cantú, Victor J, Salido, Rodolfo A, Huang, Shi, Rahman, Gibraan, Tsai, Rebecca, Valentine, Holly, Magallanes, Celestine G, Aigner, Stefan, Baer, Nathan A, Barber, Tom, Belda-Ferre, Pedro, Betty, Maryann, Bryant, MacKenzie, Maya, Martin Casas, Castro-Martínez, Anelizze, Chacón, Marisol, Cheung, Willi, Crescini, Evelyn S, De Hoff, Peter, Eisner, Emily, Farmer, Sawyer, Hakim, Abbas, Kohn, Laura, Lastrella, Alma L, Lawrence, Elijah S, Morgan, Sydney C, Ngo, Toan T, Nouri, Alhakam, Ostrander, R Tyler, Plascencia, Ashley, Ruiz, Christopher A, Sathe, Shashank, Seaver, Phoebe, Shwartz, Tara, Smoot, Elizabeth W, Valles, Thomas, Yeo, Gene W, Laurent, Louise C, Fielding-Miller, Rebecca, Knight, Rob

Publikováno v: mSystems, vol 7, iss 3

UNLABELLED: Monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces is emerging as an important tool for identifying past exposure to individuals shedding viral RNA. Our past work has demonstrated that SARS-CoV-2 reverse t

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https://escholarship.org/uc/item/7gz851k8

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Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission.

Autor: Karthikeyan S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Levy JI; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., De Hoff P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Humphrey G; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Birmingham A; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Jepsen K; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Farmer S; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tubb HM; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Valles T; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tribelhorn CE; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Tsai R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Aigner S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Sathe S; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Moshiri N; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Henson B; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA., Mark AM; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Belda-Ferre P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Cheung W; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Cresini ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Eisner ER; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lastrella AL; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Marotz CA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Ostrander T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Plascencia A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Salido RA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., McDonald D; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA., Neuhard RM; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., Scioscia AL; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Student Health and Well-Being, University of California San Diego, La Jolla, CA, USA., Satterlund AM; Student Affairs, University of California San Diego, La Jolla, CA, USA., Simmons EH; Academic Affairs, University of California San Diego, La Jolla, CA, USA., Abelman DB; Return to Learn, University of California San Diego, La Jolla, CA, USA., Brenner D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Bruner JC; Return to Learn, University of California San Diego, La Jolla, CA, USA., Buckley A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ellison M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gattas J; Return to Learn, University of California San Diego, La Jolla, CA, USA., Gonias SL; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Hale M; Return to Learn, University of California San Diego, La Jolla, CA, USA., Hawkins F; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ikeda L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Jhaveri H; Return to Learn, University of California San Diego, La Jolla, CA, USA., Johnson T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kellen V; Return to Learn, University of California San Diego, La Jolla, CA, USA., Kremer B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Matthews G; Return to Learn, University of California San Diego, La Jolla, CA, USA., McLawhon RW; Return to Learn, University of California San Diego, La Jolla, CA, USA., Ouillet P; Return to Learn, University of California San Diego, La Jolla, CA, USA., Park D; Return to Learn, University of California San Diego, La Jolla, CA, USA., Pradenas A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Reed S; Return to Learn, University of California San Diego, La Jolla, CA, USA., Riggs L; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sanders A; Return to Learn, University of California San Diego, La Jolla, CA, USA., Sollenberger B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Song A; Operational Strategic Initiatives, University of California San Diego, La Jolla, CA, USA.; Return to Learn, University of California San Diego, La Jolla, CA, USA., White B; Return to Learn, University of California San Diego, La Jolla, CA, USA., Winbush T; Return to Learn, University of California San Diego, La Jolla, CA, USA., Aceves CM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Anderson C; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Hufbauer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Kurzban E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Lee J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Matteson NL; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Parker E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Perkins SA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Ramesh KS; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Robles-Sikisaka R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Schwab MA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Spencer E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Wohl S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Nicholson L; Scripps Health, San Diego, La Jolla, CA, USA., McHardy IH; Scripps Health, San Diego, La Jolla, CA, USA., Dimmock DP; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Hobbs CA; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Bakhtar O; Sharp Healthcare, San Diego, CA, USA., Harding A; Sharp Healthcare, San Diego, CA, USA., Mendoza A; Sharp Healthcare, San Diego, CA, USA., Bolze A; Helix, San Mateo, CA, USA., Becker D; Helix, San Mateo, CA, USA., Cirulli ET; Helix, San Mateo, CA, USA., Isaksson M; Helix, San Mateo, CA, USA., Schiabor Barrett KM; Helix, San Mateo, CA, USA., Washington NL; Helix, San Mateo, CA, USA., Malone JD; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Schafer AM; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Gurfield N; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Stous S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Fielding-Miller R; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Garfein RS; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Gaines T; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Anderson C; Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Martin NK; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Schooley R; Division of Infectious Disease and Global Public Health, University of California San Diego, La Jolla, CA, USA., Austin B; Sharp Healthcare, San Diego, CA, USA., MacCannell DR; Office of Advanced Molecular Detection, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kingsmore SF; Rady Children's Institute for Genomic Medicine, San Diego, CA, USA., Lee W; Helix, San Mateo, CA, USA., Shah S; County of San Diego Health and Human Services Agency, San Diego, CA, USA., McDonald E; County of San Diego Health and Human Services Agency, San Diego, CA, USA., Yu AT; COVID-19 Detection, Investigation, Surveillance, Clinical, and Outbreak Response, California Department of Public Health, Richmond, CA, USA., Zeller M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Fisch KM; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Center for Computational Biology and Bioinformatics, University of California San Diego, La Jolla, CA, USA., Longhurst C; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Biomedical Informatics, University of California San Diego, La Jolla, CA, USA., Maysent P; Office of the UC San Diego Health CEO, University of California San Diego, La Jolla, CA, USA., Pride D; Department of Pathology, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Khosla PK; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA., Laurent LC; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA, USA., Yeo GW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA., Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Knight R; Department of Pediatrics, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. robknight@ucsd.edu.

Publikováno v: Nature [Nature] 2022 Sep; Vol. 609 (7925), pp. 101-108. Date of Electronic Publication: 2022 Jul 07.

SARS-CoV-2 Distribution in Residential Housing Suggests Contact Deposition and Correlates with Rothia sp.

Autor: Cantú VJ; These authors contributed equally.; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA., Salido RA; These authors contributed equally.; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA., Huang S; Department of Pediatrics, University of California San Diego, La Jolla, CA., Rahman G; Department of Pediatrics, University of California San Diego, La Jolla, CA.; Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, CA., Tsai R; Department of Pediatrics, University of California San Diego, La Jolla, CA., Valentine H; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA., Magallanes CG; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, USA.; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA., Aigner S; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; Dept of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA., Baer NA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Barber T; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Belda-Ferre P; Department of Pediatrics, University of California San Diego, La Jolla, CA., Betty M; Department of Pediatrics, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; Rady Children's Hospital, San Diego, CA., Bryant M; Department of Pediatrics, University of California San Diego, La Jolla, CA., Maya MC; Department of Pediatrics, University of California San Diego, La Jolla, CA., Castro-Martínez A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Chacón M; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Cheung W; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; San Diego State University, San Diego, CA., Crescini ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., De Hoff P; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, USA., Eisner E; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Farmer S; Department of Pediatrics, University of California San Diego, La Jolla, CA., Hakim A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Kohn L; Herbert Wertheim School of Public Health, University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92093., Lastrella AL; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Lawrence ES; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Morgan SC; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA., Ngo TT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Nouri A; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Ostrander RT; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Plascencia A; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; Dept of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA., Ruiz CA; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Sathe S; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA.; Dept of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA., Seaver P; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Shwartz T; Department of Pediatrics, University of California San Diego, La Jolla, CA., Smoot EW; Expedited COVID Identification Environment (EXCITE) Laboratory, Department of Pediatrics, University of California San Diego, La Jolla, CA., Valles T; Department of Pediatrics, University of California San Diego, La Jolla, CA., Yeo GW; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Dept of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA., Laurent LC; Sanford Consortium of Regenerative Medicine, University of California San Diego, La Jolla, CA.; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, USA., Fielding-Miller R; Herbert Wertheim School of Public Health, University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92093., Knight R; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA, USA.; Center for Microbiome Innovation, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Dec 07. Date of Electronic Publication: 2021 Dec 07.