Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lasse Slumstrup"'
Autor:
Sascha Kopp, Jayashree Sahana, Tawhidul Islam, Asbjørn Graver Petersen, Johann Bauer, Thomas J. Corydon, Herbert Schulz, Kathrin Saar, Norbert Huebner, Lasse Slumstrup, Stefan Riwaldt, Markus Wehland, Manfred Infanger, Ronald Luetzenberg, Daniela Grimm
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Human MCF-7 breast cancer cells were exposed to a Random Positioning Machine (RPM). After 24 hours (h) the cells grew either adherently within a monolayer (AD) or within multicellular spheroids (MCS). AD and MCS populations were separately h
Externí odkaz:
https://doaj.org/article/4792f639a36f4440a59f0c9fd262c315
Autor:
Thomas J. Corydon, Vivek Mann, Lasse Slumstrup, Sascha Kopp, Jayashree Sahana, Anne Louise Askou, Nils E. Magnusson, David Echegoyen, Toke Bek, Alamelu Sundaresan, Stefan Riwaldt, Johann Bauer, Manfred Infanger, Daniela Grimm
Publikováno v:
Cellular Physiology and Biochemistry, Vol 40, Iss 1-2, Pp 1-17 (2016)
Background/Aims: Microgravity (µg) has adverse effects on the eye of humans in space. The risk of visual impairment is therefore one of the leading health concerns for NASA. The impact of µg on human adult retinal epithelium (ARPE-19) cells is unkn
Externí odkaz:
https://doaj.org/article/7215a0eadb554cd19075bd654965a977
Autor:
Stefan Riwaldt, Johann Bauer, Markus Wehland, Lasse Slumstrup, Sascha Kopp, Elisabeth Warnke, Anita Dittrich, Nils E. Magnusson, Jessica Pietsch, Thomas J. Corydon, Manfred Infanger, Daniela Grimm
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 4, p 528 (2016)
Microgravity induces three-dimensional (3D) growth in numerous cell types. Despite substantial efforts to clarify the underlying mechanisms for spheroid formation, the precise molecular pathways are still not known. The principal aim of this paper is
Externí odkaz:
https://doaj.org/article/7c3835b28c7848738558f6b19ce914a7
Autor:
Lasse Slumstrup, Susanne Eiholm, Astrid Louise Bjørn Bennedsen, Dea Natalie Munch Jepsen, Ismail Gögenur, Anne-Marie Kanstrup Fiehn
Publikováno v:
Virchows Archiv : an international journal of pathology. 480(5)
Guidelines and requirements for diagnosing pathological complete response (pCR) in rectal adenocarcinoma following neoadjuvant treatment vary, and there is currently no consensus on the appropriate number of sections to examine per formalin-fixed, pa
Autor:
Danny Mortensen, Maria Soendergaard Thoefner, Joergen Steen Agerholm, Lasse Slumstrup, Troels Staehelin Jensen, Ole Jannik Bjerrum, Mette Berendt, Jens Randel Nyengaard
Publikováno v:
Mortensen, D, Thoefner, M S, Agerholm, J S, Slumstrup, L, Jensen, T S, Bjerrum, O J, Berendt, M & Nyengaard, J R 2022, ' Dorsal horn volume loss and pain pathway changes in Cavalier King Charles Spaniels with syringomyelia, signs of pain, and phantom scratching ', Pain, vol. 163, no. 12, pp. 2365-2379 . https://doi.org/10.1097/j.pain.0000000000002630
Central neuropathic pain is a core clinical sign of syringomyelia in humans and Cavalier King Charles Spaniel (CKCS) dogs. This histopathological study used spinal cords from CKCS dogs with syringomyelia to investigate the following conditions: (1) w
Autor:
Johann Bauer, Ganna Aleshcheva, Ruth Hemmersbach, Lasse Slumstrup, Manfred Infanger, Markus Wehland, Daniela Grimm
Publikováno v:
Aleshcheva, G, Bauer, J, Hemmersbach, R, Slumstrup, L, Wehland, M, Infanger, M & Grimm, D 2016, ' Scaffold-free Tissue Formation under Real and Simulated Microgravity Conditions ', Basic & Clinical Pharmacology & Toxicology . https://doi.org/10.1111/bcpt.12561
Scaffold-free tissue formation in microgravity is a new method in regenerative medicine and an important topic in Space Medicine. In this MiniReview, we focus on recent findings in the field of tissue engineering that were observed by exposing cells
Autor:
Kathrin Saar, Lasse Slumstrup, Norbert Huebner, Jayashree Sahana, Herbert Schulz, Manfred Infanger, Tawhidul Islam, Ronald Luetzenberg, Asbjørn Graver Petersen, Daniela Grimm, Stefan Riwaldt, Johann Bauer, Markus Wehland, Sascha Kopp, Thomas J. Corydon
Publikováno v:
Scientific Reports
Kopp, S, Sahana, J, Islam, T, Petersen, A G, Bauer, J, Corydon, T J, Schulz, H, Saar, K, Huebner, N, Slumstrup, L, Riwaldt, S, Wehland, M, Infanger, M, Luetzenberg, R & Grimm, D 2018, ' The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine ', Scientific Reports, vol. 8, no. 1, 921 . https://doi.org/10.1038/s41598-017-18556-8
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Kopp, S, Sahana, J, Islam, T, Petersen, A G, Bauer, J, Corydon, T J, Schulz, H, Saar, K, Huebner, N, Slumstrup, L, Riwaldt, S, Wehland, M, Infanger, M, Luetzenberg, R & Grimm, D 2018, ' The role of NFκB in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine ', Scientific Reports, vol. 8, no. 1, 921 . https://doi.org/10.1038/s41598-017-18556-8
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Human MCF-7 breast cancer cells were exposed to a Random Positioning Machine (RPM). After 24 hours (h) the cells grew either adherently within a monolayer (AD) or within multicellular spheroids (MCS). AD and MCS populations were separately harvested,
Autor:
Daniela Grimm, Vivek Mann, Nils E. Magnusson, Johann Bauer, Lasse Slumstrup, Thomas J. Corydon, Manfred Infanger, Alamelu Sundaresan, David Echegoyen, Sascha Kopp, Toke Bek, Stefan Riwaldt, Anne Louise Askou, Jayashree Sahana
Publikováno v:
Corydon, T J, Mann, V, Slumstrup, L, Kopp, S, Sahana, J, Askou, A L, Magnusson, N E, Echegoyen, D, Bek, T, Sundaresan, A, Riwaldt, S, Bauer, J, Infanger, M & Grimm, D 2016, ' Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity ', Cellular Physiology and Biochemistry, vol. 40, no. 1-2, pp. 1-17 . https://doi.org/10.1159/000452520
Cellular Physiology and Biochemistry, Vol 40, Iss 1-2, Pp 1-17 (2016)
Cellular Physiology and Biochemistry, Vol 40, Iss 1-2, Pp 1-17 (2016)
BACKGROUND/AIMS: Microgravity (µg) has adverse effects on the eye of humans in space. The risk of visual impairment is therefore one of the leading health concerns for NASA. The impact of µg on human adult retinal epithelium (ARPE-19) cells is unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08cc9c35d663d4a7a7d130c1f241d3a3
https://pure.au.dk/portal/da/publications/reduced-expression-of-cytoskeletal-and-extracellular-matrix-genes-in-human-adult-retinal-pigment-epithelium-cells-exposed-to-simulated-microgravity(dffb5a7b-aa7a-4b16-8315-15352fbf081f).html
https://pure.au.dk/portal/da/publications/reduced-expression-of-cytoskeletal-and-extracellular-matrix-genes-in-human-adult-retinal-pigment-epithelium-cells-exposed-to-simulated-microgravity(dffb5a7b-aa7a-4b16-8315-15352fbf081f).html
Autor:
Grimm, Stefan Riwaldt, Johann Bauer, Markus Wehland, Lasse Slumstrup, Sascha Kopp, Elisabeth Warnke, Anita Dittrich, Nils Magnusson, Jessica Pietsch, Thomas Corydon, Manfred Infanger, Daniela
Publikováno v:
International Journal of Molecular Sciences; Volume 17; Issue 4; Pages: 528
Microgravity induces three-dimensional (3D) growth in numerous cell types. Despite substantial efforts to clarify the underlying mechanisms for spheroid formation, the precise molecular pathways are still not known. The principal aim of this paper is
Autor:
Thomas J. Corydon, Lasse Slumstrup, Markus Wehland, Ganna Aleshcheva, Jayashree Sahana, Nils E. Magnusson, Johann Bauer, Manfred Infanger, Sascha Kopp, Daniela Grimm, Tawhidul Islam
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Kopp, S, Slumstrup, L, Corydon, T J, Sahana, J, Aleshcheva, G, Islam, T, Magnusson, N E, Wehland, M, Bauer, J, Infanger, M & Grimm, D 2016, ' Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine ', Scientific Reports, vol. 6, 26887 . https://doi.org/10.1038/srep26887
Scientific Reports
Kopp, S, Slumstrup, L, Corydon, T J, Sahana, J, Aleshcheva, G, Islam, T, Magnusson, N E, Wehland, M, Bauer, J, Infanger, M & Grimm, D 2016, ' Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine ', Scientific Reports, vol. 6, 26887 . https://doi.org/10.1038/srep26887
Many cell types form three-dimensional aggregates (MCS; multicellular spheroids), when they are cultured under microgravity. MCS often resemble the organ, from which the cells have been derived. In this study we investigated human MCF-7 breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fcf15690b986c573f5b3fc40e1db54
https://hdl.handle.net/11858/00-001M-0000-002A-F780-811858/00-001M-0000-002A-F77E-0
https://hdl.handle.net/11858/00-001M-0000-002A-F780-811858/00-001M-0000-002A-F77E-0