Automated sequential chromogenic IHC double staining with two HRP substrates.

Autor: Kenneth Heesche Petersen, Jesper Lohse, Lasse Ramsgaard

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0207867 (2018)

Automated IHC double staining using diaminobenzidine and HRP Magenta is illustrated utilizing a new acidic block with sulfuric acid to prevent cross-reactivity. Residual cross-reactivity in double staining is determined to arise from chromogenic-boun

Externí odkaz: https://doaj.org/article/f5f3865e06364a6e9519295810c2a52f

Lack of the receptor for advanced glycation end-products attenuates E. coli pneumonia in mice.

Autor: Lasse Ramsgaard, Judson M Englert, Michelle L Manni, Pavle S Milutinovic, Julia Gefter, Jacob Tobolewski, Lauren Crum, Gina M Coudriet, Jon Piganelli, Ruben Zamora, Yoram Vodovotz, Jan J Enghild, Tim D Oury

Publikováno v: PLoS ONE, Vol 6, Iss 5, p e20132 (2011)

The receptor for advanced glycation end-products (RAGE) has been suggested to modulate lung injury in models of acute pulmonary inflammation. To study this further, model systems utilizing wild type and RAGE knockout (KO) mice were used to determine

Externí odkaz: https://doaj.org/article/8a1e9715cde34dad8fe7e205664e7ee7

The Folding of Human Active and Inactive Extracellular Superoxide Dismutases Is an Intracellular Event

Autor: Lasse Ramsgaard, Tim D. Oury, Torsten Nygaard Kristensen, Steen V. Petersen, Jan J. Enghild, Niels Christian Nielsen, Jane S. Petersen, James D. Crapo

Publikováno v: Petersen, S V, Kristensen, T, Petersen, J S, Ramsgaard, L, Oury, T, Crapo, J, Nielsen, N C & Enghild, J J 2008, ' The folding of human active and inactive extracellular superoxide dismutase is an intracellular event ', Journal of Biological Chemistry, vol. 283, no. 22, pp. 15031 . https://doi.org/10.1074/jbc.M801548200

Human extracellular superoxide dismutase (EC-SOD) is a tetrameric glycoprotein responsible for the removal of superoxide generated in the extracellular space. Two different folding variants of EC-SOD exist based on the disulfide bridge connectivity,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d132567d8069a7f70aff8750f02ca9
https://doi.org/10.1074/jbc.m801548200

Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products

Autor: N.S. Mason, Judson M. Englert, Pavle S. Milutinovic, Tim D. Oury, Louis J. Sparvero, Lauren T. Crum, Lasse Ramsgaard, Jan J. Enghild, Michael T. Lotze

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e88259 (2014)
PLoS ONE
Milutinovic, P S, Englert, J M, Crum, L T, Mason, N S, Ramsgaard, L, Enghild, J J, Sparvero, L J, Lotze, M T & Oury, T D 2014, ' Clearance kinetics and matrix binding partners of the receptor for advanced glycation end products ', PLOS ONE, vol. 9, no. 3, pp. e88259 . https://doi.org/10.1371/journal.pone.0088259

Elucidating the sites and mechanisms of sRAGE action in the healthy state is vital to better understand the biological importance of the receptor for advanced glycation end products (RAGE). Previous studies in animal models of disease have demonstrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9397f4f1078ac9f09f3aa01753d1f1e
http://europepmc.org/articles/PMC3958346?pdf=render

The role of the receptor for advanced glycation end-products in a murine model of silicosis

Autor: Jacob M. Tobolewski, Adriana S. Leme, Jan J. Enghild, A. Murat Kaynar, Tim D. Oury, Steven D. Shapiro, Cheryl L. Fattman, Lauren Tomai, Judson M. Englert, Lasse Ramsgaard

Publikováno v: Ramsgaard, L, Englert, J M, Tobolewski, J, Tomai, L, Fattman, C L, Leme, A S, Kaynar, A M, Shapiro, S D, Enghild, J J & Oury, T D 2010, ' The role of the receptor for advanced glycation end-products in a murine model of silicosis ', P L o S One, vol. 5, no. 3, pp. e9604 . https://doi.org/10.1371/journal.pone.0009604
PLoS ONE, Vol 5, Iss 3, p e9604 (2010)
PLoS ONE

Udgivelsesdato: 2010-null BACKGROUND: The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a3e6133381e568b34a39840b7e08c5
https://pure.au.dk/ws/files/48531540/journal.pone.0009604.pdf