Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lasse N. Waehrens"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 50:211-217
Lactadherin is an opsonin, which binds with high affinity to phosphatidylserine exposed on the surface of apoptotic cells via its C1C2 domains. Phagocytosis of the apoptotic cells is then facilitated by an Arg-Gly-Asp (RGD)- mediated binding to macro
Autor:
Jørgen Frøkiær, Michael Rehling, Lasse N. Waehrens, Lise Falborg, Jan Alsner, Henrik Bluhme, Jan T. Rasmussen, Christian W. Heegaard, Michael R. Horsman
Publikováno v:
Falborg, L, Waehrens, L N, Alsner, J, Bluhme, H, Frøkiaer, J, Heegaard, C W, Horsman, M R, Rasmussen, J T & Rehling, M 2010, ' Biodistribution of 99mTc-HYNIC-lactadherin in mice-a potential tracer for visualizing apoptosis in vivo ', Scandinavian Journal of Clinical & Laboratory Investigation, vol. 70, no. 3, pp. 209-16 . https://doi.org/10.3109/00365511003663648
Udgivelsesdato: 2010-Apr-19 INTRODUCTION: The aim of this study was to establish a radio synthesis of (99m)Tc-HYNIC-lactadherin for in vivo studies and to perform biodistribution analysis studies in mice, comparing (99m)Tc-HYNIC-lactadherin to (99m)T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b20136610cd74dbc4142c958b72f1ff
https://pure.au.dk/portal/da/publications/biodistribution-of-99mtchyniclactadherin-in-mice--a-potential-tracer-for-visualizing-apoptosis-in-vivo(81e01d50-9c1c-11df-8c1a-000ea68e967b).html
https://pure.au.dk/portal/da/publications/biodistribution-of-99mtchyniclactadherin-in-mice--a-potential-tracer-for-visualizing-apoptosis-in-vivo(81e01d50-9c1c-11df-8c1a-000ea68e967b).html
Autor:
Gary E. Gilbert, Jialan Shi, Lasse N. Waehrens, Christian W. Heegaard, Jan T. Rasmussen, Yinan Shi
Publikováno v:
Shi, J, Shi, Y, Wæhrens, L N, Rasmussen, J T, Heegaard, C W & Gilbert, G E 2006, ' Lactadherin Detects Early Phosphatidylserine Exposure on Immortalized Leukemia Cells Undergoing Programmed Cell Death ', Cytometry A, vol. 69, no. 12, pp. 1193-1201 .
Aarhus University
Aarhus University
Background: Phosphatidylserine (PS) appears on the outer membrane leaflet of cells undergoing programmed cell death and marks those cells for clearance by macrophages. Macrophages secrete lactadherin, a PS-binding protein, which tethers apoptotic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f860863b01db0d07a26680f03428bc7
https://pure.au.dk/portal/da/publications/lactadherin-detects-early-phosphatidylserine-exposure-on-immortalized-leukemia-cells-undergoing-programmed-cell-death(32f1ef30-c5aa-11db-bee9-02004c4f4f50).html
https://pure.au.dk/portal/da/publications/lactadherin-detects-early-phosphatidylserine-exposure-on-immortalized-leukemia-cells-undergoing-programmed-cell-death(32f1ef30-c5aa-11db-bee9-02004c4f4f50).html
Publikováno v:
Aarhus University
Wæhrens, L N, Heegaard, C W, Gilbert, G E & Rasmussen, J T 2009, ' Bovine Lactadherin as a Calcium-independent Imaging Agent of Phosphatidylserine Expressed on the Surface of Apoptotic HeLa Cells ', Journal of Histochemistry and Cytochemistry, vol. 57, no. 10, pp. 907-914 .
Wæhrens, L N, Heegaard, C W, Gilbert, G E & Rasmussen, J T 2009, ' Bovine Lactadherin as a Calcium-independent Imaging Agent of Phosphatidylserine Expressed on the Surface of Apoptotic HeLa Cells ', Journal of Histochemistry and Cytochemistry, vol. 57, no. 10, pp. 907-914 .
Bovine lactadherin holds a stereo-specific affinity for phosphatidylserine (PS) membrane domains and binds at PS concentrations lower than the benchmark PS probe, annexin V. Accordingly, lactadherin has recognized PS exposure on preapoptotic immortal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e9fd15c37435651e7dbf8950dc91d8
https://pure.au.dk/portal/en/publications/bovine-lactadherin-as-a-calciumindependent-imaging-agent-of-phosphatidylserine-expressed-on-the-surface-of-apoptotic-hela-cells(349011f0-fac2-11de-9c17-000ea68e967b).html
https://pure.au.dk/portal/en/publications/bovine-lactadherin-as-a-calciumindependent-imaging-agent-of-phosphatidylserine-expressed-on-the-surface-of-apoptotic-hela-cells(349011f0-fac2-11de-9c17-000ea68e967b).html