Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN

Autor: Danson Vasanthan Muttuvelu, Lasse Jørgensen Cehofski, Jeppe Holtz, Tor Paaske Utheim, Xiangjun Chen, Henrik Vorum, Steffen Heegaard, Marie Louise Roed Rasmussen, Asif Manzoor Khan, Ahmed Basim Abduljabar, Bent Honoré

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 20, p 15115 (2023)

Meibomian gland dysfunction (MGD) is a highly prevalent condition and the most common cause of evaporative dry eye disease. Studying the proteome of MGD can result in important advances in the management of the condition. Here, we collected tear film

Externí odkaz: https://doaj.org/article/718938ce384b497ba3a4aeeb6aec60f8

Laser-Induced Porcine Model of Experimental Retinal Vein Occlusion: An Optimized Reproducible Approach

Autor: Mads Odgaard Mæng, Nirrooja Roshanth, Anders Kruse, Jonas Ellegaard Nielsen, Benedict Kjærgaard, Bent Honoré, Henrik Vorum, Lasse Jørgensen Cehofski

Publikováno v: Medicina, Vol 59, Iss 2, p 243 (2023)

Retinal vein occlusion (RVO) is a frequent visually disabling condition. The management of RVO continues to challenge clinicians. Macular edema secondary to RVO is often recurrent, and patients typically require intravitreal injections for several ye

Externí odkaz: https://doaj.org/article/4fd0aa17351b4ad9b90325a98e5c7dd0

Aflibercept Intervention in Experimental Branch Retinal Vein Occlusion Results in Upregulation of DnaJ Homolog Subfamily C Member 17

Autor: Lasse Jørgensen Cehofski, Anders Kruse, Alexander Nørgård Alsing, Benn Falch Sejergaard, Jonas Ellegaard Nielsen, Shona Pedersen, Danson Vasanthan Muttuvelu, Svend Kirkeby, Bent Honoré, Henrik Vorum

Publikováno v: Journal of Ophthalmology, Vol 2021 (2021)

Aflibercept is an inhibitor of vascular endothelial growth factor (VEGF) used to treat macular edema following branch retinal vein occlusion (BRVO). Despite well-documented efficacy, there is limited knowledge about proteome changes following afliber

Externí odkaz: https://doaj.org/article/7ed43e36925d438e9ec9f181dab37c1f

IL-18 and S100A12 Are Upregulated in Experimental Central Retinal Vein Occlusion

Autor: Lasse Jørgensen Cehofski, Anders Kruse, Svend Kirkeby, Alexander Nørgård Alsing, Jonas Ellegaard Nielsen, Kentaro Kojima, Bent Honoré, Henrik Vorum

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 11, p 3328 (2018)

Retinal vein occlusion (RVO) is a common retinal vascular disease. RVO may be complicated by pronounced ischemia that often leads to severe loss of visual function. The present work aimed at studying the retinal proteome of RVO complicated by ischemi

Externí odkaz: https://doaj.org/article/9a3efb904b124d0ab1fbc52c2bbbc9b0

Macular Edema in Central Retinal Vein Occlusion Correlates With Aqueous Fibrinogen Alpha Chain

Autor: Lasse Jørgensen Cehofski, Kentaro Kojima, Natsuki Kusada, Maja Rasmussen, Danson Vasanthan Muttuvelu, Jakob Grauslund, Henrik Vorum, Bent Honoré

Publikováno v: Cehofski, L J, Kojima, K, Kusada, N, Rasmussen, M, Muttuvelu, D V, Grauslund, J, Vorum, H & Honoré, B 2023, ' Macular Edema in Central Retinal Vein Occlusion Correlates With Aqueous Fibrinogen Alpha Chain ', Investigative ophthalmology & visual science, vol. 64, no. 2, 23 . https://doi.org/10.1167/iovs.64.2.23
Cehofski, L J, Kojima, K, Kusada, N, Rasmussen, M, Muttuvelu, D V, Grauslund, J, Vorum, H & Honoré, B 2023, ' Macular Edema in Central Retinal Vein Occlusion Correlates With Aqueous Fibrinogen Alpha Chain ', Investigative Ophthalmology & Visual Science, vol. 64, no. 2, 23 . https://doi.org/10.1167/iovs.64.2.23

Purpose: The global protein profile of the aqueous humor has been found to correlate with the severity of retinal vascular disease. Studying the aqueous humor in central retinal vein occlusion (CRVO) with proteomic techniques may bring insights to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bd374b034458a5789c95b835b77810
https://pure.au.dk/portal/da/publications/macular-edema-in-central-retinal-vein-occlusion-correlates-with-aqueous-fibrinogen-alpha-chain(7c3c4c75-269f-49fc-8522-9a717ca8e740).html