Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lasse Eggers Pedersen"'
Autor:
Jay D. Keasling, Marcos Laloux, Michael Krogh Jensen, Tadas Jakočiūnas, Lasse Eggers Pedersen, Emil D. Jensen, Beata Joanna Lehka
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 49, iss 15
Jensen, E D, Laloux, M, Lehka, B J, Pedersen, L E, Jakočiūnas, T, Jensen, M K & Keasling, J D 2021, ' A synthetic RNA-mediated evolution system in yeast ', Nucleic Acids Research, vol. 49, no. 15, e88 . https://doi.org/10.1093/nar/gkab472
Nucleic acids research, vol 49, iss 15
Jensen, E D, Laloux, M, Lehka, B J, Pedersen, L E, Jakočiūnas, T, Jensen, M K & Keasling, J D 2021, ' A synthetic RNA-mediated evolution system in yeast ', Nucleic Acids Research, vol. 49, no. 15, e88 . https://doi.org/10.1093/nar/gkab472
Laboratory evolution is a powerful approach to search for genetic adaptations to new or improved phenotypes, yet either relies on labour-intensive human-guided iterative rounds of mutagenesis and selection, or prolonged adaptation regimes based on na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb76760409c774c2e16890a49ac380e7
https://doi.org/10.1093/nar/gkab472
https://doi.org/10.1093/nar/gkab472
Autor:
Esther Blanco, Massimiliano Baratelli, Maria Montoya, Jens Nielsen, Gregers Jungersen, Lars Erik Larsen, Lasse Eggers Pedersen, Ramona Trebbien
Publikováno v:
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
Baratelli, M, Pedersen, L E, Trebbien, R, Larsen, L E, Jungersen, G, Blanco, E, Nielsen, J & Montoya, M 2017, ' Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs ', Journal of General Virology, vol. 98, no. 5, pp. 895-899 . https://doi.org/10.1099/jgv.0.000748
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
Baratelli, M, Pedersen, L E, Trebbien, R, Larsen, L E, Jungersen, G, Blanco, E, Nielsen, J & Montoya, M 2017, ' Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs ', Journal of General Virology, vol. 98, no. 5, pp. 895-899 . https://doi.org/10.1099/jgv.0.000748
Heterologous protection against swine influenza viruses (SwIVs) of different lineages is an important concern for the pig industry. Cross-protection between ‘avian-like’ H1N1 and 2009 pandemic H1N1 lineages has been observed previously, indicatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04353f41ead01869d8bc5a58e880cb0b
https://doi.org/10.1099/jgv.0.000748
https://doi.org/10.1099/jgv.0.000748
Autor:
Morten Nielsen, Lasse Eggers Pedersen, Mikkel Harndahl, Gregers Jungersen, Søren Buus, Michael R. Rasmussen
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Affinity and stability of peptides bound by major histocompatibility complex (MHC) class I molecules are important factors in presentation of peptides to cytotoxic T lymphocytes (CTLs). In silico prediction methods of peptide-MHC binding followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d11fcc5ffd8cfc59dca35c142ea59a
https://doi.org/10.1007/s00251-015-0883-9
https://doi.org/10.1007/s00251-015-0883-9
Autor:
Maria Rathmann Sørensen, Chak-Sum Ho, Gregers Jungersen, Lasse Eggers Pedersen, Dorte Fink Vadekær
Publikováno v:
Veterinary Immunology and Immunopathology. 162:108-116
The swine major histocompatibility complex (MHC) genomic region (SLA) is extremely polymorphic comprising high numbers of different alleles, many encoding a distinct MHC class I molecule, which binds and presents endogenous peptides to circulating T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48194fa86eb69575526a577c34103b43
https://doi.org/10.1016/j.vetimm.2014.10.007
https://doi.org/10.1016/j.vetimm.2014.10.007
Autor:
Gregers Jungersen, Morten Nielsen, Nana Haahr Overgaard, Thomas Mørch Frøsig, Maria Rathmann Sørensen, Simon Welner, Mikael Lenz Strube, Lasse Eggers Pedersen, Ole Lund, Golde, William T., Søren Buus
Publikováno v:
Jungersen, G, Nielsen, M, Overgaard, N H, Frøsig, T M, Sørensen, M R, Welner, S, Strube, M L, Pedersen, L E, Lund, O, Golde, W T & Buus, S 2016, ' Tracking the elusive cytotoxic T cell response in pigs ' 11th International Veterinary Immunology Symposium, Gold Coast, Australia, 16/08/2016-19/08/2016, .
Technical University of Denmark Orbit
Technical University of Denmark Orbit
Quantitative and qualitative assessment of antigen-specific cytotoxic T cell (CTL) responses in pigs is not a straightforward process. Through the years we have developed a series of reagents, tools and protocols to characterize peptide-specific CTL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::25517b208c38cbe40403ecdbac68ea50
http://orbit.dtu.dk/en/publications/tracking-the-elusive-cytotoxic-t-cell-response-in-pigs(a755e4e8-0ed3-4032-9b51-fbc319ac9329).html
http://orbit.dtu.dk/en/publications/tracking-the-elusive-cytotoxic-t-cell-response-in-pigs(a755e4e8-0ed3-4032-9b51-fbc319ac9329).html
Autor:
Søren Buus, Gregers Jungersen, Morten Nielsen, Lasse Eggers Pedersen, William T. Golde, Jared R. Patch, Mikkel Harndahl
Publikováno v:
Animal Genetics. 44:251-258
Summary Characterization of the peptide-binding specificity of swine leukocyte antigen (SLA) class I and II molecules is critical to the understanding of adaptive immune responses of swine toward infectious pathogens. Here, we describe the complete b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6abc26ffe2ea1bebf2c4581452f57c
https://doi.org/10.1111/j.1365-2052.2012.02400.x
https://doi.org/10.1111/j.1365-2052.2012.02400.x
Autor:
Lasse Eggers Pedersen, Patch, J., Glabman, R., Kenney, M., Morten Nielsen, Buus, S., Gregers Jungersen, Golde, W. T.
Publikováno v:
Pedersen, L E, Patch, J, Glabman, R, Kenney, M, Nielsen, M, Buus, S, Jungersen, G & Golde, W T 2013, Monitoring Expansion of T Cell Specifities Against Foot-and-Mpouth-Disease Virus (FMDV) in Swine With MHC Class I Tetramers Following a Prime/Boost Vaccination . in 10th International Veterinary Immunology Symposium-IVIS 2013 ., CS05.5, pp. 72, 10th International Veterinary Immunology Symposium, Milano, Italy, 28/08/2013 .
Technical University of Denmark Orbit
Technical University of Denmark Orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ab64b0ad6e155dc8a87d1d4e1c516206
https://orbit.dtu.dk/en/publications/ef919bbc-c9dc-4b02-8cd8-ba979a4cb20b
https://orbit.dtu.dk/en/publications/ef919bbc-c9dc-4b02-8cd8-ba979a4cb20b
Publikováno v:
Vaccine. 30(33)
Vaccines have been a major innovation in the history of mankind and still have the potential to address the challenges posed by chronic intracellular infections including tuberculosis, HIV and malaria which are leading causes of high morbidity and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881a4997bf3f2e0b0ad6d3aab0f570b8
https://pubmed.ncbi.nlm.nih.gov/22658928
https://pubmed.ncbi.nlm.nih.gov/22658928
Publikováno v:
Pedersen, L E, Fink, D R & Jungersen, G 2012, ' Swine Leukocyte Antigen (SLA) class I allele typing of Danish swine herds and the identification of commonly expressed haplotypes using sequence specific low-and high resolution primers ' 4th European Veterinary Immunology Workshop (EVIW), Edinburgh, United Kingdom, 02/09/2012-04/09/2012, .
Technical University of Denmark Orbit
Technical University of Denmark Orbit
The genomic region (SLA) of the swine major histocompatibility complex (MHC), which bind and present endogenous peptides to circulating T cells of the immune system, is extremely polymorphic comprising high numbers of different alleles, many of which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a43252cbddc9d136dae487d31d971ef6
http://orbit.dtu.dk/en/publications/swine-leukocyte-antigen-sla-class-i-allele-typing-of-danish-swine-herds-and-the-identification-of-commonly-expressed-haplotypes-using-sequence-specific-low-and-high-resolution-primers(2a6b5451-4eb8-4e65-92a0-fb3dc6e6bb39).html
http://orbit.dtu.dk/en/publications/swine-leukocyte-antigen-sla-class-i-allele-typing-of-danish-swine-herds-and-the-identification-of-commonly-expressed-haplotypes-using-sequence-specific-low-and-high-resolution-primers(2a6b5451-4eb8-4e65-92a0-fb3dc6e6bb39).html
Autor:
Lasse Eggers Pedersen, Michael Rasmussen, Mikkel Harndahl, Morten Nielsen, Søren Buus, Gregers Jungersen
Publikováno v:
Pedersen, L E, Rasmussen, M, Harndahl, M, Nielsen, M, Buus, S & Jungersen, G 2012, ' From Viral genome to specific peptide epitopes-Methods for identifying porcine T cell epitopes based on in silico predictions, in vitro identification and ex vivo verification ', 4th European Veterinary Immunology Workshop (EVIW), Edinburgh, United Kingdom, 02/09/2012-04/09/2012 .
Technical University of Denmark Orbit
Technical University of Denmark Orbit
The affinity for and stability of peptides bound by major histocompatibility complex (MHC) class I molecules are instrumental factors in presentation of viral epitopes to cytotoxic T lymphocytes (CTLs). In swine, such peptide presentations by swine l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::35aabfd3f5e6db6334aeefbde7b1303d
https://orbit.dtu.dk/en/publications/090857fa-c053-4259-8451-1a06e824e1b7
https://orbit.dtu.dk/en/publications/090857fa-c053-4259-8451-1a06e824e1b7