Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells

Autor: Hasyeoui, Mohamed, Lassagne, Frédéric, Erb, William, Nael, Manal, Elokely, Khaled M., Chaikuad, Apirat, Knapp, Stefan, Jorda, Adrian, Vallés, Soraya L., Quissac, Emie, Verreault, Maïté, Robert, Thomas, Bach, Stéphane, Samarat, Ali, Mongin, Florence

Publikováno v: In Bioorganic Chemistry May 2023 134

Thiazolo[5,4‐f]quinoxalines, Oxazolo[5,4‐f]quinoxalines and Pyrazino[b,e]isatins: Synthesis from 6‐Aminoquinoxalines and Properties.

Autor: Lassagne, Frédéric¹ (AUTHOR) frederic.lassagne@univ-rennes1.fr, Sims, Joshua M.^1,2 (AUTHOR), Erb, William¹ (AUTHOR), Mongin, Olivier¹ (AUTHOR), Richy, Nicolas¹ (AUTHOR), El Osmani, Nour³ (AUTHOR), Fajloun, Ziad^3,4 (AUTHOR) ziad.fajloun@ul.edu.lb, Picot, Laurent⁵ (AUTHOR) laurent.picot@univ-lr.fr, Thiéry, Valérie⁵ (AUTHOR), Robert, Thomas^6,7 (AUTHOR), Bach, Stéphane^6,7,8 (AUTHOR) bach@sb-roscoff.fr, Dorcet, Vincent¹ (AUTHOR), Roisnel, Thierry¹ (AUTHOR), Mongin, Florence¹ (AUTHOR) florence.mongin@univ-rennes1.fr

Publikováno v: European Journal of Organic Chemistry. 5/20/2021, Vol. 2021 Issue 19, p2756-2763. 8p.

Copper- and Cobalt-Catalyzed Syntheses of Thiophene-Based Tertiary Amines

Autor: Bouarfa, Salima, Graβl, Simon, Ivanova, Maria, Langlais, Timothy, Bentabed-Ababsa, Ghenia, Lassagne, Frédéric, Erb, William, Roisnel, Thierry, Dorcet, Vincent, Knochel, Paul, Mongin, Florence

Publikováno v: European Journal of Organic Chemistry
European Journal of Organic Chemistry, 2019, 2019 (20), pp.3244-3258. ⟨10.1002/ejoc.201900276⟩
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2019, 2019 (20), pp.3244-3258. ⟨10.1002/ejoc.201900276⟩

International audience; Thienylzinc halides and related compounds prepared by deprotonation followed by transmetalation were used in copper-catalyzed amination using N-benzoyloxy secondary amines. By extending the reaction to 1,5-naphthyridine, it wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e958ecbd24b9cfaff7c75845f562a2a7
https://univ-rennes.hal.science/hal-02177982

Saccharin as an Organocatalyst for Quinoxalines and Pyrido[2,3- b ]pyrazines Syntheses.

Autor: Lassagne, Frédéric¹ (AUTHOR) frederic.lassagne@univ-rennes1.fr, Chevallier, Floris¹ (AUTHOR), Mongin, Florence¹ (AUTHOR)

Publikováno v: Synthetic Communications. Jan2014, Vol. 44 Issue 1, p141-149. 9p.

A convenient synthesis of 3- and 5-amino-1 H-pyrazoles via 3(5)-amino-4-(ethylsulfinyl)-1 H-pyrazole desulfinylation.

Autor: Lassagne, Frédéric¹ frederic.lassagne@univ-rennes1.fr, Snégaroff, Katia¹, Roisnel, Thierry², Nassar, Ekhlass³, Mongin, Florence¹

Publikováno v: Heterocyclic Communications. 2011, Vol. 17 Issue 3/4, p139-145. 7p. 5 Diagrams, 3 Charts.