Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc.

Autor: Fuchs R; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria. Electronic address: robert.fuchs@medunigraz.at., Stracke A; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria., Holzmann V; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria; FH JOANNEUM - University of Applied Sciences, Alte Poststraße 149, 8020 Graz, Austria., Luschin-Ebengreuth G; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria., Meier-Allard N; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria., Ebner N; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria., Lassacher TM; Chair of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Heinrichstraße 31, 8010 Graz, Austria., Absenger-Novak M; Centre for Medical Research, Medical University of Graz, Stiftingtalstrasse 24, 8010 Graz, Austria., Fröhlich E; Centre for Medical Research, Medical University of Graz, Stiftingtalstrasse 24, 8010 Graz, Austria., Schittmayer M; Research Unit Functional Proteomics and Metabolic Pathways, Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria; Omics Center Graz, BioTechMed-Graz, Stiftingtalstrasse 24, 8010 Graz, Austria., Cano Crespo S; Institute for Research in Biomedicine (IRB-Barcelona), Barcelona Institute of Science and Technology (BIST), Department of Biochemistry and Molecular Biomedicine, University of Barcelona, and CIBERER, Parc Científic de Barcelona. Baldiri I Reixac 10-12, 08028 Barcelona, Spain., Palacin M; Institute for Research in Biomedicine (IRB-Barcelona), Barcelona Institute of Science and Technology (BIST), Department of Biochemistry and Molecular Biomedicine, University of Barcelona, and CIBERER, Parc Científic de Barcelona. Baldiri I Reixac 10-12, 08028 Barcelona, Spain., Rinner B; Biomedical Research, Medical University of Graz, Roseggerweg 48, 8036 Graz, Austria., Birner-Gruenberger R; Research Unit Functional Proteomics and Metabolic Pathways, Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria; Omics Center Graz, BioTechMed-Graz, Stiftingtalstrasse 24, 8010 Graz, Austria.

Publikováno v: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2018 Sep; Vol. 1865 (9), pp. 1211-1229. Date of Electronic Publication: 2018 Jun 15.