Septic Shock Requiring Three Vasopressors: Patient Demographics and Outcomes

Autor: Gloria H. Kwak, PhD, Rajapaksha W. M. A. Madushani, PhD, Lasith Adhikari, PhD, April Y. Yan, BS, Eric S. Rosenthal, MD, Kahina Sebbane, MS, Zahia Yanes, MS, David Restrepo, BS, Adrian Wong, PharmD, MPH, FCCM, Leo A. Celi, MD, MS, MPH, Emmett A. Kistler, MD, MHQS

Publikováno v: Critical Care Explorations, Vol 6, Iss 11, p e1167 (2024)

OBJECTIVES:. Septic shock is a common condition necessitating timely management including hemodynamic support with vasopressors. Despite the high prevalence and mortality, there is limited data characterizing patients who require three or more vasopr

Externí odkaz: https://doaj.org/article/bec9d6a408654704ab01c0d8aabc0e68

Nonconvex Regularization-Based Sparse Recovery and Demixing With Application to Color Image Inpainting

Autor: Fei Wen, Lasith Adhikari, Ling Pei, Roummel F. Marcia, Peilin Liu, Robert C. Qiu

Publikováno v: IEEE Access, Vol 5, Pp 11513-11527 (2017)

This paper addresses the recovery and demixing problem of signals that are sparse in some general dictionary. Involved applications include source separation, image inpainting, super-resolution, and restoration of signals corrupted by clipping, satur

Externí odkaz: https://doaj.org/article/e54fb796b3d945088582508162c77104

Systematic Review and Comparison of Publicly Available ICU Data Sets-A Decision Guide for Clinicians and Data Scientists

Autor: Christopher M. Sauer, Tariq A. Dam, Leo A. Celi, Martin Faltys, Miguel A. A. de la Hoz, Lasith Adhikari, Kirsten A. Ziesemer, Armand Girbes, Patrick J. Thoral, Paul Elbers

Publikováno v: Sauer, C M, Dam, T A, Celi, L A, Faltys, M, de la Hoz, M A A, Adhikari, L, Ziesemer, K A, Girbes, A, Thoral, P J & Elbers, P 2022, ' Systematic Review and Comparison of Publicly Available ICU Data Sets-A Decision Guide for Clinicians and Data Scientists ', Critical Care Medicine, vol. 50, no. 6, pp. E581-E588 . https://doi.org/10.1097/CCM.0000000000005517
Crit Care Med
Sauer, Christopher M; Dam, Tariq A; Celi, Leo A; Faltys, Martin; de la Hoz, Miguel A A; Adhikari, Lasith; Ziesemer, Kirsten A; Girbes, Armand; Thoral, Patrick J; Elbers, Paul (2022). Systematic Review and Comparison of Publicly Available ICU Data Sets-A Decision Guide for Clinicians and Data Scientists. Critical care medicine, 50(6), e581-e588. Wolters Kluwer Health 10.1097/CCM.0000000000005517

OBJECTIVE As data science and artificial intelligence continue to rapidly gain traction, the publication of freely available ICU datasets has become invaluable to propel data-driven clinical research. In this guide for clinicians and researchers, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f56e1503a68526b376c3bfb7160657
https://research.vumc.nl/en/publications/6abe6763-59fd-40c3-8947-5832129b06ba

Early Biomarker Signatures in Surgical Sepsis

Autor: R.W.M.A. Madushani, Vishal Patel, Tyler Loftus, Yuanfang Ren, Han Jacob Li, Laura Velez, Quran Wu, Lasith Adhikari, Philip Efron, Mark Segal, Tezcan Ozrazgat-Baslanti, Parisa Rashidi, Azra Bihorac

Publikováno v: The Journal of surgical research. 277

Sepsis has complex, time-sensitive pathophysiology and important phenotypic subgroups. The objective of this study was to use machine learning analyses of blood and urine biomarker profiles to elucidate the pathophysiologic signatures of subgroups of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f99c83f17ad2b8a29ea1e3a4f14d26
https://pubmed.ncbi.nlm.nih.gov/35569215

Discovery and Validation of Urinary Molecular Signature of Early Sepsis

Autor: Rajesh Mohandas, Azra Bihorac, Larysa Sautina, Mark S. Segal, Philip A. Efron, Lyle L. Moldawer, Ferdous Kadri, Frederick A. Moore, Henry V. Baker, Laura M Velez, Parisa Rashidi, Lasith Adhikari, Sabyasachi Bandyopadhyay, Ricardo Ungaro, Nicholas Lysak, Maria-Cecilia Lopez, Tezcan Ozrazgat-Baslanti, Scott C. Brakenridge, Ying-Chih Peng

Publikováno v: Critical Care Explorations

Supplemental Digital Content is available in the text.
Objectives: Identify alterations in gene expression unique to systemic and kidney-specific pathophysiologic processes using whole-genome analyses of RNA isolated from the urinary cells of se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6bebdad7129f877c3baf4f32d2e01e
https://pubmed.ncbi.nlm.nih.gov/33063018