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pro vyhledávání: '"Lashawn Drew"'
Publikováno v:
Nucleic Acids Research. 28:2823-2830
The molecular mechanisms which govern the develop-mental specificity of human beta-globin gene transcription have been studied in K562 cells, a human eyrthroleukemia line that expresses minimal beta-globin. Protein-binding analysis reveals that the 5
Autor:
Wulin Aerbajinai, Griffin P. Rodgers, Lashawn Drew, Ling Chen, Jiangqiong Zhu, Kyung Chin, Wenli Liu
Publikováno v:
British journal of haematology. 143(3)
The human olfactomedin 4 gene (OLFM4, also known as hGC-1, GW112) is thought to be a useful marker for early myeloid development. To understand the molecular mechanisms underlying granulocyte colony-stimulating factor (G-CSF)-stimulated OLFM4 express
Publikováno v:
Blood cells, moleculesdiseases. 24(3)
Our investigations have focused on localizing cis-elements responsible for the down regulation of the adult beta-like globin genes (delta and beta) in immature, or primitive erythroid tissues. We studied their activity after transfection into K562 ce