Výsledky vyhledávání - "Larysa Poluben"

Data from WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth

Autor: Steven P. Balk, Xin Yuan, Xiaoping Zhang, Fang Xie, Olga Voznesensky, Larysa Poluben, Andreas Varkaris, Yun Wang, Seiji Arai, Fen Ma, Keshan Wang

Noncanonical Wnt signaling by WNT5a has oncogenic and tumor suppressive activities, but downstream pathways mediating these specific effects remain to be fully established. In a subset of prostate cancer organoid culture and xenograft models, inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627c2ea1f8b9f17cadf4c8854e853833
https://doi.org/10.1158/0008-5472.c.6487383.v1

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WNT5a Signaling through ROR2 Activates the Hippo Pathway to Suppress YAP1 Activity and Tumor Growth

Autor: Keshan Wang, Fen Ma, Seiji Arai, Yun Wang, Andreas Varkaris, Larysa Poluben, Olga Voznesensky, Fang Xie, Xiaoping Zhang, Xin Yuan, Steven P. Balk

Publikováno v: Cancer research.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a82e0299a964cff161e0dc3a7f6707
https://pubmed.ncbi.nlm.nih.gov/36622276

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MOLECULAR GENETIC ABNORMALITIES IN THE GENOME OF PATIENTS WITH Ph-NEGATIVE MYELOPROLIFERATIVE NEOPLASIA AFFECTED BY IONIZING RADIATION AS A RESULT OF THE CHORNOBYL NUCLEAR ACCIDENT

Autor: Paula G. Fraenkel, C Balk, S V Klymenko, Larysa Poluben, Oleksandr Shumeiko, L V Neumerzhytska

Publikováno v: Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology. 25:362-373

to determine the frequency of major somatic mutations in the JAK2, MPL and CALR genes in the genomeof patients with Ph-negative myeloproliferative neoplasms that occur in individuals who have been exposed to ionizing radiation as a result of the Chor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b432bc1ed84015f828faed67f165ec02
https://doi.org/10.33145/2304-8336-2020-25-362-373

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MUTATIONS OF GENES BRCA1 AND BRCA2 IN WOMEN WITH OVARIAN CANCER EXPOSED TO FACTORS OF CHORNOBYL NUCLEAR ACCIDENT

Autor: L A Rybchenko, Larysa Poluben, G M Bychkova, S V Klymenko, G V Stephanovych

Publikováno v: Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology. 24:455-464

to determine a frequency of germline mutations 185delAG, 5382insC in BRCA1 gene and 6174delT in BRCA2 gene in Ukrainian patients with OC including women who were exposed to the factors of Chornobyl nuclear accident.In the study we enrolled 306 OC pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3068db00266a3ac948b7a3c01f2c8a4d
https://doi.org/10.33145/2304-8336-2019-24-455-464

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Autocrine Canonical Wnt Signaling Primes Noncanonical Signaling through ROR1 in Metastatic Castration-Resistant Prostate Cancer

Autor: Fen Ma, Seiji Arai, Keshan Wang, Carla Calagua, Amanda R. Yuan, Larysa Poluben, Zhongkai Gu, Joshua W. Russo, David J. Einstein, Huihui Ye, Meng Xiao He, Yu Liu, Eliezer Van Allen, Adam G. Sowalsky, Manoj K. Bhasin, Xin Yuan, Steven P. Balk

Publikováno v: Cancer Res

Wnt signaling driven by genomic alterations in genes including APC and CTNNB, which encodes β-catenin, have been implicated in prostate cancer development and progression to metastatic castration-resistant prostate cancer (mCRPC). However, nongenomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4857ddfb427508dce7e54dcd5bd8b2
https://pubmed.ncbi.nlm.nih.gov/35131873

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Androgen receptor splice variant 7 functions independently of the full length receptor in prostate cancer cells

Autor: LiYang Wang, Joshua W. Russo, Mannan Nouri, Larysa Poluben, Jiaqian Liang, Laura Cato, Olga Voznesensky, Shaoyong Chen, Xin Yuan, Steven P. Balk, Henry W. Long, Seiji Arai, Lisha Xie, Myles Brown

Publikováno v: Cancer Lett

One mechanism for reactivation of androgen receptor (AR) activity after androgen deprivation therapy in castration-resistant prostate cancer (CRPC) is expression of splice variants such as ARv7 that delete the ligand binding domain and have constitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229e6a6ec855a3b8c6198d59f849983d
https://pubmed.ncbi.nlm.nih.gov/34256096

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