Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Larsson, Omberg"'
Autor:
Jennie S. Lavine, Anthony D. Scotina, Seth Haney, Jessie P. Bakker, Elena S. Izmailova, Larsson Omberg
Publikováno v:
Frontiers in Digital Health, Vol 6 (2024)
IntroductionParkinson's Disease affects over 8.5 million people and there are currently no medications approved to treat underlying disease. Clinical trials for disease modifying therapies (DMT) are hampered by a lack of sufficiently sensitive measur
Externí odkaz:
https://doaj.org/article/d65414c98f3d486591f5c240318e8861
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background The two-way partial AUC has been recently proposed as a way to directly quantify partial area under the ROC curve with simultaneous restrictions on the sensitivity and specificity ranges of diagnostic tests or classifiers. The met
Externí odkaz:
https://doaj.org/article/7607bf5da99d4d4fb9b41cc133e6c970
Autor:
Sabine Schootemeijer, Nienke M. de Vries, Eric A. Macklin, Kit C.B. Roes, Hilde Joosten, Larsson Omberg, Alberto Ascherio, Michael A. Schwarzschild, Bastiaan R. Bloem
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Exercise has various health benefits for people with Parkinson’s disease (PD). However, implementing exercise into daily life and long-term adherence remain challenging. To increase a sustainable engagement with physical activit
Externí odkaz:
https://doaj.org/article/d24b24c9ffe94219a39c40a3949d4aeb
Autor:
Chao Yan, Yao Yan, Zhiyu Wan, Ziqi Zhang, Larsson Omberg, Justin Guinney, Sean D. Mooney, Bradley A. Malin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. In this work, the authors introduce a use case oriented benchmarking fra
Externí odkaz:
https://doaj.org/article/7f00928d11944926bd2b00764b67250b
Autor:
Sean M. Gross, Mark A. Dane, Rebecca L. Smith, Kaylyn L. Devlin, Ian C. McLean, Daniel S. Derrick, Caitlin E. Mills, Kartik Subramanian, Alexandra B. London, Denis Torre, John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Cemal Erdem, Nicholas Lyons, Ted Natoli, Sarah Pessa, Xiaodong Lu, James Mullahoo, Jonathan Li, Miriam Adam, Brook Wassie, Moqing Liu, David F. Kilburn, Tiera A. Liby, Elmar Bucher, Crystal Sanchez-Aguila, Kenneth Daily, Larsson Omberg, Yunguan Wang, Connor Jacobson, Clarence Yapp, Mirra Chung, Dusica Vidovic, Yiling Lu, Stephan Schurer, Albert Lee, Ajay Pillai, Aravind Subramanian, Malvina Papanastasiou, Ernest Fraenkel, Heidi S. Feiler, Gordon B. Mills, Jake D. Jaffe, Avi Ma’ayan, Marc R. Birtwistle, Peter K. Sorger, James E. Korkola, Joe W. Gray, Laura M. Heiser
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Comprehensive profiling of ligand-induced perturbation responses of the MCF10A mammary epithelial cell line provides an exhaustive resource for identification of the molecular basis of cellular phenotypes.
Externí odkaz:
https://doaj.org/article/50400b000ed946209179e826cd85298c
Autor:
Solveig K Sieberts, Henryk Borzymowski, Yuanfang Guan, Yidi Huang, Ayala Matzner, Alex Page, Izhar Bar-Gad, Brett Beaulieu-Jones, Yuval El-Hanani, Jann Goschenhofer, Monica Javidnia, Mark S Keller, Yan-Chak Li, Mohammed Saqib, Greta Smith, Ana Stanescu, Charles S Venuto, Robert Zielinski, BEAT-PD DREAM Challenge Consortium, Arun Jayaraman, Luc J W Evers, Luca Foschini, Alex Mariakakis, Gaurav Pandey, Nicholas Shawen, Phil Synder, Larsson Omberg
Publikováno v:
PLOS Digital Health, Vol 2, Iss 3, p e0000208 (2023)
One of the promising opportunities of digital health is its potential to lead to more holistic understandings of diseases by interacting with the daily life of patients and through the collection of large amounts of real-world data. Validating and be
Externí odkaz:
https://doaj.org/article/de8633dcf1574d1da3521a42bf309186
Autor:
Alex Page, Norman Yung, Peggy Auinger, Charles Venuto, Alistair Glidden, Eric Macklin, Larsson Omberg, Michael A. Schwarzschild, E. Ray Dorsey
Publikováno v:
Digital Biomarkers, Vol 6, Iss 1, Pp 1-8 (2022)
Background: Smartphones can generate objective measures of Parkinson’s disease (PD) and supplement traditional in-person rating scales. However, smartphone use in clinical trials has been limited. Objective: This study aimed to determine the feasib
Externí odkaz:
https://doaj.org/article/f908f9e07a3249b8bcfc073aa5584d1f
Autor:
Solveig K. Sieberts, Jennifer Schaff, Marlena Duda, Bálint Ármin Pataki, Ming Sun, Phil Snyder, Jean-Francois Daneault, Federico Parisi, Gianluca Costante, Udi Rubin, Peter Banda, Yooree Chae, Elias Chaibub Neto, E. Ray Dorsey, Zafer Aydın, Aipeng Chen, Laura L. Elo, Carlos Espino, Enrico Glaab, Ethan Goan, Fatemeh Noushin Golabchi, Yasin Görmez, Maria K. Jaakkola, Jitendra Jonnagaddala, Riku Klén, Dongmei Li, Christian McDaniel, Dimitri Perrin, Thanneer M. Perumal, Nastaran Mohammadian Rad, Erin Rainaldi, Stefano Sapienza, Patrick Schwab, Nikolai Shokhirev, Mikko S. Venäläinen, Gloria Vergara-Diaz, Yuqian Zhang, the Parkinson’s Disease Digital Biomarker Challenge Consortium, Yuanjia Wang, Yuanfang Guan, Daniela Brunner, Paolo Bonato, Lara M. Mangravite, Larsson Omberg
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-12 (2021)
Abstract Consumer wearables and sensors are a rich source of data about patients’ daily disease and symptom burden, particularly in the case of movement disorders like Parkinson’s disease (PD). However, interpreting these complex data into so-cal
Externí odkaz:
https://doaj.org/article/45ee48713e9b4dd591d3f8cc81d31894
Autor:
Ruth B. Schneider, Larsson Omberg, Eric A. Macklin, Margaret Daeschler, Lauren Bataille, Shalini Anthwal, Taylor L. Myers, Elizabeth Baloga, Sidney Duquette, Phil Snyder, Katherine Amodeo, Christopher G Tarolli, Jamie L. Adams, Katherine F Callahan, Joshua Gottesman, Catherine M. Kopil, Codrin Lungu, Alberto Ascherio, James C. Beck, Kevin Biglan, Alberto J. Espay, Caroline Tanner, David Oakes, Ira Shoulson, Dan Novak, Elise Kayson, Earl Ray Dorsey, Lara Mangravite, Michael A. Schwarzschild, Tanya Simuni, the Parkinson Study Group AT‐HOME PD Investigators
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 2, Pp 308-320 (2021)
Abstract Objective The expanding power and accessibility of personal technology provide an opportunity to reduce burdens and costs of traditional clinical site‐centric therapeutic trials in Parkinson’s disease and generate novel insights. The val
Externí odkaz:
https://doaj.org/article/7feb687f3d094d1c9e817ead9428641d
Autor:
Gloria Vergara-Diaz, Jean-Francois Daneault, Federico Parisi, Chen Admati, Christina Alfonso, Matilde Bertoli, Edoardo Bonizzoni, Gabriela Ferreira Carvalho, Gianluca Costante, Eric Eduardo Fabara, Naama Fixler, Fatemah Noushin Golabchi, John Growdon, Stefano Sapienza, Phil Snyder, Shahar Shpigelman, Lewis Sudarsky, Margaret Daeschler, Lauren Bataille, Solveig K. Sieberts, Larsson Omberg, Steven Moore, Paolo Bonato
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-12 (2021)
Measurement(s) body movement coordination trait • Movement Disorder Society Unified Parkinson’s Disease Rating Scale Questionnaire • Medication • motor coordination/balance trait • sleep pattern • MDS-UPDRS Tasks and Simulated Activities
Externí odkaz:
https://doaj.org/article/a1838ff67bb344efa15fa460e087cb43